β1-Glycoprotein (SP-1) in maternal serum as a diagnostic aid in ectopic pregnancy

1980 ◽  
Vol 10 (1) ◽  
pp. 229-231
Author(s):  
Wolfgang Eiermann ◽  
Gerd Grenner ◽  
Klaus Sterzik ◽  
Francesco Dati
1978 ◽  
pp. 257-258
Author(s):  
Alex A. Bezjian ◽  
Robert Safinski

2018 ◽  
Vol 7 (4) ◽  
pp. 467-470
Author(s):  
Wasan Wajdi Ibrahim ◽  
Afraa Mahjoob Al-Naddawi ◽  
Hayder A. Fawzi

Objectives: Assessment of glycodelin (GD) as a marker for unruptured ectopic pregnancy (EP) in the first trimester of pregnancy. Materials and Methods: This case-control study was conducted during June 2016 to May 2017 in the Obstetrics and Gynecological Department of Baghdad University at Baghdad teaching hospital/medical city complex. In this study, 100 pregnant women in their first trimester of pregnancy were included after clinical and ultrasonic findings. Results: Based on the results, GD levels in EP were significantly lower than those with normal intrauterine pregnancy (1.58 ± 1.18 vs. 30.1 ± 11.9). In addition, using receiver operator curve analysis, the cut-off GD level of 9.5 and less had acceptable validity results (100% sensitivity, 100% specificity, 95% positive predictive value, 100% negative predictive value, and accuracy 100%) to predict EP. Conclusions: In general, serum GD is considered as an excellent predictor of unruptured EP.


1981 ◽  
Vol 27 (1) ◽  
pp. 133-134 ◽  
Author(s):  
J E Haddow ◽  
E M Kloza ◽  
G J Knight ◽  
D E Smith

Abstract Maternal serum alpha-fetoprotein concentrations are influenced by maternal weight during the second trimester. Heavier pregnant women have lower median values, apparently as a result of a diluting effect of larger blood volume. This phenomenon is of clinical interest because alpha-fetoprotein concentration in a pregnant woman's serum is one of the factors considered in assessing risk of poor outcome. A revision of the reference interval for alpha-fetoprotein to take body weight into account might improve its use as a diagnostic aid, especially in heavier women.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Alexandros Daponte ◽  
Efthimios Deligeoroglou ◽  
Spyros Pournaras ◽  
Christos Hadjichristodoulou ◽  
Antonios Garas ◽  
...  

Given the present lack of clinically useful tests for the accurate diagnosis of ectopic pregnancy (EP), there is a need to select out those immunological factors measured in the maternal serum, as potential biomarkers. Our assumption was that C1q/anti-C1q antibody complexes and serum levels of interleukin-15 (IL-15) may play a role in differentiating abortions (MAs) and EPs and normal pregnancies. We assessed whether their measurement could set the diagnosis in a case control study at 6–8 weeks consisting of 60 women with failed early pregnancy (30 EPs, 30 MAs) and 33 women with intrauterine pregnancies. Normal pregnancies contain anti-C1q antibodies more frequently compared to women with failed pregnancies, the lowest levels being found in EPs, but this lacked statistical significance and anti-C1q could not serve as a marker. However EP pregnancies had elevated IL-15 levels that could statistically significantly differentiate them from MAs and IUPs. Furthermore, when assessing IL-15 for the clinically important differentiation between IUP and EP, we found at a cut-off of 16 pg/mL a negative predictive value of 99 with a sensitivity for diagnosing an EP of 92%. According to these results, serum IL-15 is a promising marker differentiating an MA from an EP.


1988 ◽  
Vol 43 (2) ◽  
pp. 84-85
Author(s):  
JACQUES GUILLAUME ◽  
FRED BENJAMIN ◽  
BERNARD SICURANZA ◽  
CHUN FU WANG ◽  
ALFREDO GARCIA ◽  
...  

Author(s):  
Emile Darai ◽  
Georges Vlastos ◽  
Jean Louis Benifla ◽  
Didier Sitbon ◽  
Jacqueline Hassid ◽  
...  

1989 ◽  
Vol 4 (7) ◽  
pp. 835-836 ◽  
Author(s):  
I. Stabile ◽  
F. Olajide ◽  
T. Chard ◽  
J.G. Grudzinskas

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