Peritubular capillary, interstitium, and lymph of the renal cortex

1984 ◽  
pp. 183-202 ◽  
Author(s):  
G. G. Pinter ◽  
K. Gärtner
Keyword(s):  
Renal Cortex ◽  
Peritubular Capillary

Effects of some vasodilator drugs on transcapillary fluid exchange in renal cortex

1976 ◽  
Vol 230 (4) ◽  
pp. 1148-1158 ◽  
Author(s):  
C Baylis ◽  
WM Deen ◽  
BD Myers ◽  
BM Brenner
Keyword(s):  
Plasma Flow ◽  
Renal Cortex ◽  
Hydraulic Pressure ◽  
Oncotic Pressure ◽  
Drug Infusion ◽  
Peritubular Capillary ◽  
Fluid Exchange ◽  
Single Nephron ◽  
Glomerular Ultrafiltration ◽  
Opposing Effects

In 23 Munich-Wistar rats with surface glomeruli, the determinants of glomerular ultrafiltration and peritubular capillary uptake of proximal reabsorbate were studied before and during intra-arterial infusions of mildly vasodepressor doses of prostaglandin E1,acetylcholine, and bradykinin. For each drug single-nephron glomerular filtration rate remained unchanged from normal hydropenic values while glomerular plasma flow rate increased, resulting in declines in single-nephron filtration fraction (SNFF). Mean glomerular transcapillary hydraulic pressure difference (delta P) increased or remained unchanged on average. Declines in SNFF were accompanied by reductions in efferent arteriolar oncotic pressure (piE). Filtration pressure equilibrium, equality between pi E and delta P, obtained before but not during drug infusions. In the latter situation values for the glomerular capillary ultrafiltration coefficient were calculated and found to be significantly reduced from published control values. Despite marked falls in pi E during drug infusion, absolute proximal reabsorption was not reduced significantly, due, it is suggested, to the opposing effects of increases in efferent arteriolar plasma flow and interstitial hydraulic pressure.

Control of proximal tubule acidification by the endothelium of the peritubular capillaries

1997 ◽  
Vol 272 (2) ◽  
pp. R691-R694 ◽  
Author(s):  
C. Amorena ◽  
A. F. Castro
Keyword(s):  
Nitric Oxide ◽  
Proximal Tubule ◽  
Renal Cortex ◽  
Peritubular Capillary ◽  
Proximal Tubule Cells ◽  
Peritubular Capillaries ◽  
Tubule Lumen ◽  
Tubule Cells ◽  
Convoluted Tubules ◽  
Stimulation Of

Guanosine 3',5'-cyclic monophosphate (cGMP), a nitric oxide mediator, stimulates Na+/H+ exchange in brush-border vesicles of the renal cortex. The aim of the present work was to test whether the endothelium of the peritubular capillaries modulated the rate of proximal luminal acidification through the release of endothelium-derived nitric oxide (EDNO). Perfusion of the tubule lumen with dibutyryl cGMP increased net proton flux (J(H)). Two agents that elicit EDNO production, bradykinin (BK) and carbamylcholine (Cch), increased J(H) when added to the peritubular capillary perfusate. Bradykinin did not affect J(H) when the peritubular capillaries and the lumen were perfused with Na-free solution. Methylene blue (MB) and N(G)-nitro-L-arginine methyl ester (L-NAME) blocked the elevation in J(H) by Cch and also decreased basal J(H). Bradykinin increased cGMP content of isolated proximal convoluted tubules, but only if they were coincubated with endothelial cells. This effect of BK was blocked by L-NAME. The results suggest that the endothelium of the peritubular capillaries affects proximal tubule acidification through changes of cGMP in proximal tubule cells, probably via stimulation of Na+/H+ exchanger.

Hemoglobin crystals of the red blood cells in the human renal cortex: electron microscopic observations of the renal lithiasis

1978 ◽  
Vol 36 (2) ◽  
pp. 480-481
Author(s):  
Kosuke Ueda ◽  
Hiroto Washida ◽  
Nakazo Watari
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Renal Cortex ◽  
Uranyl Acetate ◽  
Osmic Acid ◽  
Renal Lithiasis ◽  
Electron Microscopic ◽  
Hemoglobin C ◽  
First Case ◽  
Ultrathin Sections

IntroductionHemoglobin crystals in the red blood cells were electronmicroscopically reported by Fawcett in the cat myocardium. In the human, Lessin revealed crystal-containing cells in the periphral blood of hemoglobin C disease patients. We found the hemoglobin crystals and its agglutination in the erythrocytes in the renal cortex of the human renal lithiasis, and these patients had no hematological abnormalities or other diseases out of the renal lithiasis. Hemoglobin crystals in the human erythrocytes were confirmed to be the first case in the kidney.Material and MethodsTen cases of the human renal biopsies were performed on the operations of the seven pyelolithotomies and three ureterolithotomies. The each specimens were primarily fixed in cacodylate buffered 3. 0% glutaraldehyde and post fixed in osmic acid, dehydrated in graded concentrations of ethanol, and then embedded in Epon 812. Ultrathin sections, cut on LKB microtome, were doubly stained with uranyl acetate and lead citrate.

1615: Direct Visualization of Cortical Peritubular Capillary in Human Transplanted Kidney after Reperfusion Injury Using Magnifying Endoscopy

2005 ◽  
Vol 173 (4S) ◽  
pp. 437-438
Author(s):  
Masashi Kato ◽  
Ryohei Hattori ◽  
Tokunori Yamamoto ◽  
Minako Hagikura ◽  
Yoshinari Ono
Keyword(s):  
Reperfusion Injury ◽  
Magnifying Endoscopy ◽  
Direct Visualization ◽  
Peritubular Capillary ◽  
Transplanted Kidney

Comparative Chemical, Biological and Clinical Studies of 99mTc-Glucoheptonate and 99mTc-Dimercaptosucci- nate as Used in Renal Scintigraphy

1979 ◽  
Vol 18 (01) ◽  
pp. 40-45 ◽  
Author(s):  
M. Malešević ◽  
Lj. Stefanović ◽  
N. Vanlić-Razumenić
Keyword(s):  
Clinical Studies ◽  
Gamma Camera ◽  
Radiochemical Purity ◽  
Renal Cortex ◽  
Renal Scintigraphy ◽  
Time Intervals ◽  
Experimental Animals ◽  
Dynamic Studies

The renal radiopharmaceutical preparations 99mTc-DMS and 99mTc-GH were examined chemically, biologically and clinically. Both preparations are of high radiochemical purity. The biodistribution of both preparations was examined in experimental animals at different time intervals, from 15 min to 4 hr; the percentage of incorporation of 99mTc-DMS into kidneys is much higher (29.4% to 52.0%) than that of 99mTc-GH (12.80% to 22.20%). Both preparations accumulate to a greater extent in the renal cortex than in the medulla.The most suitable time for renal scintigraphy for "mTc-DMS is 90-150 min while for 99mTc-GH it is 60-90 min. It is concluded that 99mTc-DMS is more suitable for static scintigrams on the scanner and 99mTc-GH for dynamic studies with the gamma camera.

The Employment of 197Hg EDTA in Kidney Scanning

1965 ◽  
Vol 05 (01) ◽  
pp. 56-67
Author(s):  
I. Pál ◽  
J. Földes ◽  
I. Krasznai
Keyword(s):  
Radiation Dose ◽  
Renal Cortex ◽  
Radiation Doses ◽  
Intravenous Pyelography ◽  
Edta Complex

SummaryThe authors investigated the use of 197Hg EDTA complex for kidney scanning. They describe the physical, biological and toxicological properties of the compound; its distribution within the organism, its excretion with urine and faeces and its uptake by the kidneys. The authors have established that the renal cortex selectively secretes the material which makes it suitable for kidney scanning. Some scintigrams of both normal and pathologic kidneys are presented.Finally a detailed discussion of the dosimetry is included. The radiation doses due to 197Hg EDTA are compared with those due to 203Hg-neohydrin and to intravenous pyelography. This comparison shows clearly that the use of 197Hg EDTA considerably decreases the radiation dose to the patient.

Immunochemical detection of advanced glycation end products in renal cortex from STZ-induced diabetic rat

Diabetes ◽  
1993 ◽  
Vol 42 (6) ◽  
pp. 826-832 ◽  
Author(s):  
T. Mitsuhashi ◽  
H. Nakayama ◽  
T. Itoh ◽  
S. Kuwajima ◽  
S. Aoki ◽  
...  
Keyword(s):  
Advanced Glycation End Products ◽  
Renal Cortex ◽  
Diabetic Rat ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Immunochemical Detection

Reduced albumin in the renal cortex of ethylene glycol-treated rats

ScienceAsia ◽  
2014 ◽  
Vol 40 (1) ◽  
pp. 35 ◽  
Author(s):  
Jui-Lung Shen ◽  
Kee-Ming Man ◽  
Yung-Hsiang Chen ◽  
Chiao-Hui Chang ◽  
Yuan-Ju Lee ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Renal Cortex
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