Influence of muscle strength, physical activity and weight on bone mass in a population-based sample of 1004 elderly women

2003 ◽  
Vol 14 (9) ◽  
pp. 768-772 ◽  
Author(s):  
P. Gerdhem ◽  
K. A. M. Ringsberg ◽  
K. �kesson ◽  
K. J. Obrant
1997 ◽  
Vol 68 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Henrik Düppe ◽  
Per Gärdsell ◽  
Olof Johnell ◽  
Bo E Nilsson ◽  
Karin Ringsberg

2016 ◽  
Vol 105 (10) ◽  
pp. 1216-1224 ◽  
Author(s):  
Jesper Fritz ◽  
Björn E. Rosengren ◽  
Magnus Dencker ◽  
Caroline Karlsson ◽  
Magnus K. Karlsson

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 543-544
Author(s):  
Marguerita Saadeh ◽  
Amaia Calderón-Larrañaga ◽  
Davide Vetrano ◽  
Philip von Rosen ◽  
Anna-Karin Welmer

Abstract Physical function and physical activity have been associated with health outcomes related to the cardiopulmonary and immune systems, but the extent to which they are related to the risk of developing COVID-19-like symptoms remains unclear. We aimed to explore these associations among Swedish older adults. We analyzed data from 904 individuals aged ≥68 years from the population-based Swedish National study on Aging and Care in Kungsholmen. COVID-19-like symptoms were assessed by phone interview (March-June 2020) and included fever, cough, sore throat and/or a cold, headache, pain in muscles, legs and joints, loss of taste and/or odour, breathing difficulties, chest pain, gastrointestinal symptoms and eye inflammation. Muscle strength, mobility, and physical activity were objectively examined in 2016-2018. Data were analyzed using logistic regression models and stratifying by age. During the first outbreak of the pandemic, 325 (36%) individuals from our sample developed COVID-19-like symptoms. Those with longer time to perform the chair stand test had an odds ratio (OR) of 1.5 (95% confidence interval [CI] 1.1-2.1) for presenting with COVID-19-like symptoms compared to those with a faster time to perform the test, after adjusting for potential confounders. The risk was even higher among people aged ≥80 years (OR: 2.6; 95% CI 1.5-4.7). No significant associations were found for walking speed or moderate-to-vigorous physical activity. A weaker muscle strength, especially among the oldest-old adults, may contribute to higher odds of developing COVID-19-like symptoms, emphasizing the need to maintain sufficient levels of muscle strength in old age.


1998 ◽  
Vol 83 (12) ◽  
pp. 4274-4279 ◽  
Author(s):  
G. Jones ◽  
T. Dwyer

Retrospective studies have suggested that the prepubertal years may be an important window of opportunity to increase bone mass, but there have been few direct studies and little exploration of gender differences in this age group. In this study, we report the associations among physical activity measures, sunlight exposure, body composition, and bone mass in 8-yr-old children. We studied 330 children in 1996 (115 girls and 215 boys; response rate, 60%) who had previously taken part in a cohort study of cot death in 1988. They had measurement of anthropometrics (height, weight, and body composition), sunlight exposure (by questionnaire), and physical activity[ questionnaire, muscle strength by dynamometry, and bicycle ergometric physical work capacity at a pulse of 170 beats/min (PWC170)]. Bone mineral density (BMD) was assessed at the spine, femoral neck, and total body by a Hologic QDR2000 densitometer. In females only, PWC170[ hip, 2.4%/quartile (95% confidence interval (CI), 0.3–4.5); spine, 1.7%/quartile (95% CI, 0.0–3.4); size adjusted] was associated with BMD, whereas in males only, BMD was associated with both sports participation (hip, 4.2% (95% CI, 1.1–7.3); spine, 4.3% (95% CI, 0.9–7.7)] and muscle strength [hip, 1.7%/quartile (95% CI, 0.0–3.4); but not spine; size adjusted]. Winter sunlight exposure was associated with BMD in girls [hip, 2.9%/category (95% CI, 0.7–5.0); spine, 3.6%/category (95% CI, 1.4–5.8)], but not in boys [hip, 0.3%/category (95% CI, −1.4 to +2.0); spine, 1.4%/category (95% CI, −0.7 to +3.5)]. Males and females were very similar in body size. However, males had higher size-adjusted BMD at the hip (9.6%; 95% CI, 6.9–14), whereas females had higher size-adjusted BMD at the spine (3.2%; 95% CI, 0.8–5.6%). In conclusion, this study has suggested that physical activity and exposure to sunlight are important in the bone mineralization of prepubertal male and female children. The magnitude of both gender and environmental differences in bone mass in this age group is substantial, suggesting that modification at this stage of life may influence peak bone mass and possibly fracture risk in later life.


1999 ◽  
Vol 84 (9) ◽  
pp. 3025-3029 ◽  
Author(s):  
Kim Thorsen ◽  
Peter Nordström ◽  
Ronny Lorentzon ◽  
Gösta H. Dahlén

Osteoporosis is the most common metabolic bone disease. A low peak bone mass is regarded a risk factor for osteoporosis. Heredity, physical activity, and nutrition are regarded important measures for the observed variance in peak bone mass. Lp(a) lipoprotein is a well-known risk factor for atherosclerosis. Serum insulin-like growth factor I (IGF-I) has been found to be increased in males with early cardiovascular disease. In this study, we evaluated the association between bone mass, body constitution, muscle strength, Lp(a), and IGF-I in 47 Caucasian male adolescents (mean age, 16.9 yr). Bone mineral density (BMD) and body composition were measured by dual x-ray absorptiometry, muscle strength of thigh using an isokinetic dynamometer, IGF-I by RIA, and Lp(a) by enzyme-linked immunosorbent assay. IGF-I was only associated with Lp(a) (r = 0.38, P < 0.01). Lp(a) was related to total body (r= 0.40, P < 0.01), skull (r = 0.45, P < 0.01), and femoral neck BMD (r = 0.44, P < 0.01). Lp(a) was also related to fat mass (r = 0.34, P < 0.05) and muscle strength (r = 0.30–0.42, P < 0.05). After multiple regression and principal component (PC) analysis, the so-called PC body size (weight, fat mass, lean body mass, and muscle strength) was the most significant predictor of BMD (β = 0.28–0.51, P < 0.05–0.01), followed by the so-called PC physical activity (β = 0.28–0.38, P < 0.05–0.01, weight-bearing locations). However, the PC analysis confirmed that Lp(a) was an independent predictor of total body, skull, and femoral neck BMD (β = 0.33–0.36, P < 0.01). The present investigation confirms that BMD, body size, and muscle strength are closely related and that the level of physical activity is a major determinant of BMD. However, the positive relation of Lp(a), a major risk factor for cardiovascular disease, to BMD has not previously been described. The importance of this observation has to be further investigated.


2004 ◽  
Vol 79 (4) ◽  
pp. 552-557 ◽  
Author(s):  
Yves Rolland ◽  
Valérie Lauwers-Cances ◽  
Marco Pahor ◽  
Judith Fillaux ◽  
Hélène Grandjean ◽  
...  

2016 ◽  
Vol 105 (10) ◽  
pp. 1127-1128 ◽  
Author(s):  
Luis Gracia-Marco

Author(s):  
Björn E. Rosengren ◽  
Erik Lindgren ◽  
Lars Jehpsson ◽  
Magnus Dencker ◽  
Magnus K. Karlsson

AbstractDaily school physical activity (PA) improves musculoskeletal traits. This study evaluates whether the benefits remain 4 years after the intervention. We followed 45 boys and 36 girls who had had 40 min PA/school day during the nine compulsory school years and 21 boys and 22 girls who had had 60 min PA/school week (reference), with measurements at baseline and 4 years after the program terminated. Bone mineral content (BMC; g) and bone mineral density (BMD; g/cm2) were measured by dual-energy X-ray absorptiometry and knee flexion peak torque relative to total body weight (PTflexTBW) at a speed of 180 degrees/second with a computerized dynamometer. Group differences are presented as mean differences (adjusted for sex and duration of follow-up period) with 95% confidence intervals. The total gain bone mass [mean difference in spine BMC +32.0 g (14.6, 49.4) and in arms BMD of +0.06 g/cm2 (0.02, 0.09)] and gain in muscle strength [mean difference in PTflex180TBW +12.1 (2.0, 22.2)] were greater in the intervention than in the control group. There are still 4 years after the intervention indications of benefits in both bone mass and muscle strength gain. Daily school PA may counteract low bone mass and inferior muscle strength in adult life. ClinicalTrials.gov.NCT000633828 retrospectively registered 2008-11-03


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