Posterior brain sensorimotor recruitment for inhibition of delayed responses in children

Author(s):  
Kristina T. R. Ciesielski ◽  
Christopher Bouchard ◽  
Isabel Solis ◽  
Brian A. Coffman ◽  
Davood Tofighi ◽  
...  
Keyword(s):  
2018 ◽  
Author(s):  
Manel Naifar ◽  
Mouna Turki ◽  
Achraf Ammar ◽  
Faten Haj Kacem ◽  
Mohamed Abid ◽  
...  

Author(s):  
Michael H. Glantz ◽  
Gregory E. Pierce

AbstractCurrent discussions of the social phenomenon of “vaccine hesitancy” with regard to Covid-19 provide an opportunity to use hesitancy as a means to shift thinking about untimely and delayed responses to forecasts of hydrometeorological hazards. Hesitancy, that is, provides a paradigm through which such regrettably delayed responses to hydromet hazards might be better understood and effectively addressed. Without exaggeration, just about every hydromet event provides an example of how hesitancy hinders individual, community, and national government risk-reducing preventive and mitigative responses to forecasts of foreseeable, relatively near-term climate, water, or weather hazards. Reasons for such hesitancy (for vaccine and forecast use alike) include—among others—lack of trust in the science, lack of confidence in government, and persistent concern about the uncertainties that surround forecasting—both meteorological and public health. As such, a better understanding of the causes that lead to individual and group hesitancy can better inform hydromet forecasters and affected communities about ways in which beneficial actions in response to timely forecasts are often delayed. This better understanding will facilitate, where necessary, targeted interventions to enhance the societal value of forecasting by reducing this long-observed challenge of “forecast hesitancy.” First, this article focuses on incidents of “vaccine hesitancy” that, for various reasons, people around the world are even now experiencing with regard to several now-available, and confirmed efficacious, Covid-19 vaccines. Reports of such incidents of indecisiveness first increased dramatically over the first few months of 2021, despite the strong scientific confidence that vaccination would significantly lower personal risk of contracting as well as spreading the virus. After, the notion of forecast hesitancy with regard to hydrometeorological hazards is discussed.It’s not what you say, it’s what people hear.-Frank Luntz (2007)


2020 ◽  
Vol 713 ◽  
pp. 136619 ◽  
Author(s):  
Verónica Granados ◽  
Cayetano Gutiérrez-Cánovas ◽  
Rebeca Arias-Real ◽  
Biel Obrador ◽  
Astrid Harjung ◽  
...  

1979 ◽  
Vol 109 (6) ◽  
pp. 989-998 ◽  
Author(s):  
Barbara Cooney O'Brien ◽  
Raju Pullarkat ◽  
Jerry Darsie ◽  
Raymond Reiser

Vision ◽  
2019 ◽  
Vol 3 (3) ◽  
pp. 40 ◽  
Author(s):  
Alfred Lim ◽  
Vivian Eng ◽  
Caitlyn Osborne ◽  
Steve M. J. Janssen ◽  
Jason Satel

Inhibition of return is characterized by delayed responses to previously attended locations when the cue-target onset asynchrony (CTOA) is long enough. However, when cues are predictive of a target’s location, faster reaction times to cued as compared to uncued targets are normally observed. In this series of experiments investigating saccadic reaction times, we manipulated the cue predictability to 25% (counterpredictive), 50% (nonpredictive), and 75% (predictive) to investigate the interaction between predictive endogenous facilitatory (FCEs) and inhibitory cueing effects (ICEs). Overall, larger ICEs were seen in the counterpredictive condition than in the nonpredictive condition, and no ICE was found in the predictive condition. Based on the hypothesized additivity of FCEs and ICEs, we reasoned that the null ICEs observed in the predictive condition are the result of two opposing mechanisms balancing each other out, and the large ICEs observed with counterpredictive cueing can be attributed to the combination of endogenous facilitation at uncued locations with inhibition at cued locations. Our findings suggest that the endogenous activity contributed by cue predictability can reduce the overall inhibition observed when the mechanisms occur at the same location, or enhance behavioral inhibition when the mechanisms occur at opposite locations.


1992 ◽  
Vol 263 (3) ◽  
pp. R679-R684
Author(s):  
J. B. Dean ◽  
J. A. Boulant

Thermoregulatory responses may be delayed in onset and offset by several minutes after changes in hypothalamic temperature. Our preceding study found neurons that displayed delayed firing rate responses during clamped thermal stimulation in remote regions of rat diencephalic tissue slices. The present study looked for similar delayed firing rate responses during clamped (1.5-10 min) changes in each neuron's local temperature. Of 26 neurons tested with clamped thermal stimulation, six (i.e., 23%) showed delayed responses, with on-latencies of 1.0-7.8 min. These neurons rarely showed off-latencies, and the delayed response was not eliminated by synaptic blockade. The on-latencies and ranges of local thermosensitivity were similar to delayed neuronal responses to remote temperature; however, remote-sensitive neurons displayed off-latencies, higher firing rates at 37 degrees C, and greater sensitivity to thermal stimulation. Our findings suggest that delayed thermosensitivity is an intrinsic property of certain neurons and may initiate more elaborate or prolonged delayed responses in synaptically connected diencephalic networks. These networks could explain the delayed thermoregulatory responses observed during hypothalamic thermal stimulation.


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