Effect of Yerbimat Herbicide on Lipid Peroxidation, Catalase Activity, and Histological Damage in Gills and Liver of the Freshwater Fish Goodea Atripinnis

Pollutants entering plants cells are able to cause biochemical malfunction, including lipid peroxidation, which leads to the change in antioxidant system activity. Sustaining redox balance in cells is a required condition of plants survival in conditions of anthropogenic pollution. The goal of this research was the investigation of catalase activity in meadow grass, wild vetch, red clover, coltsfoot and chamomile near various factories of Tyumen. Plants were gathered near the highway as well as close to the metallurgical plant, engine factory, oil refinery and accumulator plants. The change in catalase activity in the cells of plants turned out to be species-specific. The decrease in catalase activity was observed in the meadow grass and wild vetch cells, while in coltsfoot, red clover and chamomile both decrease and increase in enzyme activity was obtained. Pollutants from all the examined factories affected more or less on the catalase activity, but the greatest effect was registered near the metallurgical factory, that probably related to high heavy metal concentration in plants. The lowest effect on catalase activity, compared to control, was observed near the highway.

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Lipid Peroxidation, Lipid Profile Changes and Antioxidant Properties of the Combination of Vernonia amygdalina and Ficus exasperata on the Blood, Liver and Kidney of Alloxan-Induced Diabetic Rats

Asian Journal of Biochemistry, Genetics and Molecular Biology ◽

10.9734/ajbgmb/2021/v8i130187 ◽

2021 ◽

pp. 37-47

Author(s):

Ukperoro Uyoyo Jeremiah ◽

Awarota Ruth Oghogho ◽

Oroye Otsuko ◽

Udeze Maria Chizoba

Keyword(s):

Lipid Peroxidation ◽

Lipid Profile ◽

Catalase Activity ◽

Risk Index ◽

Antioxidant Properties ◽

Diabetic Rats ◽

Atherogenic Index ◽

Hepatic Enzymes ◽

Vernonia Amygdalina ◽

Control Serum

Background: The use of plants known to possess significant antioxidant activities have been widely recommended in the complementary and alternate system of medicine in the treatment of diabetes mellitus. Among the many plant used in Nigeria for the management of DM are Vernonia amygdalina and Ficus exasperata. This study was designed to assess the effect of the combination of the aqueous extract of Vernonia amygdalina and Ficus exasperata on blood glucose level, lipid profile, hepatic enzymes, lipid peroxidation and antioxidant status in alloxan-induced diabetes in rats. Method: Twenty five rats were divided into five groups. Four groups were made diabetic by the intra-peritoneal administration of alloxan monohydrate (150mg/kg body weight) while the fifth group served as normal control. Serum, hepatic and renal concentrations of reduced glutathione (GSH) and thiobarbituric acid reactive substances (TBARS) as well as the catalase activity were determined. The blood lipid profile and some hepatic enzymes were also studied. Result: The combined extract lowered lipid peroxidation, increase glutathione concentration and catalase activity in all the tissues of diabetic rats. The individual extract lowered the total cholesterol LDL-Cholesterol, coronary risk index (CRI), and atherogenic index (AI) while increasing the concentration of HDL cholesterol in alloxan-induced diabetic rats. Diabetes lowered hepatic enzymes’ activities but the leaf extract significantly increased it. Conclusion: It can be concluded that combination of the extracts showed additive effect on each other and it is highly recommended for the management of diabetes.

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15.P7. Effects of mercury on the antioxidant enzyme activities and lipid peroxidation in the gills of the freshwater fish matrinxã, Brycon cephalus

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology ◽

10.1016/j.cbpa.2007.06.164 ◽

2007 ◽

Vol 148 ◽

pp. S64

Author(s):

D.A. Monteiro ◽

F.T. Rantin ◽

A.L. Kalinin

Keyword(s):

Lipid Peroxidation ◽

Antioxidant Enzyme ◽

Freshwater Fish ◽

Enzyme Activities ◽

Antioxidant Enzyme Activities

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The Mechanisms of Glutamine- and Fish Oil-Supplemented Resuscitation Fluids on Alleviating Oxidative Stress of the Lung and Liver in Rats with Trauma-Hemorrhagic Shock

Current Developments in Nutrition ◽

10.1093/cdn/nzaa045_062 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 429-429

Author(s):

Bing-Xiang Liu ◽

Hui-Chen Lo ◽

Chien-Hsing Lee

Keyword(s):

Oxidative Stress ◽

Lipid Peroxidation ◽

Fish Oil ◽

Hemorrhagic Shock ◽

Catalase Activity ◽

Caspase 3 ◽

Neutrophil Infiltration ◽

Midline Laparotomy ◽

Shed Blood ◽

Main Factor

Abstract Objectives Oxidative stress has been demonstrated to be the cause of cellular and organ damage in patients with trauma hemorrhagic shock and reperfusion (THR). Our previous study showed that resuscitation fluids supplemented with glutamine and fish oil, the antioxidants with anti-inflammatory activities, may alleviate systemic inflammatory response and oxidative stress in the THR rats. The aim of this study was to further investigate the mechanisms of these supplements on alleviating THR-induced damage in the lung and liver, i.e., the 2 vulnerable organs in THR. Methods Male Wistar rats were suffered with 5 cm midline laparotomy and 2 catheterizations in the left carotid artery and right jugular vein individually for blood drawn to a mean arterial pressure 30 to 35 mmHg for 60 minutes and for resuscitation of shed blood and lactate Ringer's solution with or without L-alanyl-L-glutamine (13.5 mmole/kg/day) and/or fish oil (0.5 g/kg/day) within 10 minutes. The different resuscitation fluids were continuous infused (∼1.4 ml/h) for 42 hr. Normal healthy rats and intubation sham-operated rats were included as controls. Results In the lung, the THR-increased lipid peroxidation and toll-like receptor 4 (TLR4) were significantly decreased by glutamine with or without fish oil (one-way ANOVA, P < 0.05). Fish oil was the main factor to decrease myeloperoxidase and activated caspase 3 in the lung of the THR rats (two-way ANOVA, P < 0.05). In the liver, the THR-increased lipid peroxidation and TLR4 and the THR-decreased catalase activity were improved by glutamine and/or fish oil. In addition, fish oil was the main factor to decrease inducible and endothelial nitric oxide synthase (NOS) and to increase IkB and phosphorylated NF-kB and glutamine was the main factor to decrease activated caspase 3 in the liver of the THR rats. Conclusions These results suggest that fish oil may alleviate neutrophil infiltration and NOS activation and fish oil and glutamine may elevate catalase activity and alleviate apoptosis to attenuate the THR-induced damage in the lung and liver. Funding Sources MOST 102-2320-B-030-005-MY3.

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Responses of antioxidant enzymes, lipid peroxidation, and Na+/K+-ATPase in liver of the fish Goodea atripinnis exposed to Lake Yuriria water

Fish Physiology and Biochemistry ◽

10.1007/s10695-010-9453-0 ◽

2010 ◽

Vol 37 (3) ◽

pp. 511-522 ◽

Cited By ~ 28

Author(s):

Eugenia López-López ◽

Jacinto Elías Sedeño-Díaz ◽

Claudia Soto ◽

Liliana Favari

Keyword(s):

Lipid Peroxidation ◽

Antioxidant Enzymes ◽

Goodea Atripinnis

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Toxicity of the Herbicide Atrazine: Effects on Lipid Peroxidation and Activities of Antioxidant Enzymes in the Freshwater Fish Channa Punctatus (Bloch)

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph7083298 ◽

2010 ◽

Vol 7 (8) ◽

pp. 3298-3312 ◽

Cited By ~ 107

Author(s):

Christopher Ddidigwu Nwani ◽

Wazir Singh Lakra ◽

Naresh Sahebrao Nagpure ◽

Ravindra Kumar ◽

Basdeo Kushwaha ◽

...

Keyword(s):

Lipid Peroxidation ◽

Antioxidant Enzymes ◽

Freshwater Fish ◽

Channa Punctatus ◽

Herbicide Atrazine

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Effects of Cypermethrin on Antioxidant Enzyme Activities and Lipid Peroxidation in Liver and Kidney of the Freshwater Fish, and (L.)

Bulletin of Environmental Contamination and Toxicology ◽

10.1007/s00128-001-0174-z ◽

2001 ◽

Vol 67 (5) ◽

pp. 0657-0664 ◽

Cited By ~ 56

Author(s):

N. Üner ◽

E. Özcan Oruç ◽

M. Canli ◽

Y. Sevgler

Keyword(s):

Lipid Peroxidation ◽

Antioxidant Enzyme ◽

Freshwater Fish ◽

Enzyme Activities ◽

Antioxidant Enzyme Activities ◽

Liver And Kidney

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Characterization of Oxidative Stress in Various Tissues of Diabetic and Galactose-fed Rats

International Journal of Experimental Diabetes Research ◽

10.1155/edr.2001.211 ◽

2001 ◽

Vol 2 (3) ◽

pp. 211-216 ◽

Cited By ~ 6

Author(s):

Robert M. Strother ◽

Tonya G. Thomas ◽

Mary Otsyula ◽

Ruth A. Sanders ◽

John B. Watkins III

Keyword(s):

Oxidative Stress ◽

Lipid Peroxidation ◽

Superoxide Dismutase ◽

Glutathione Peroxidase ◽

Rat Model ◽

Catalase Activity ◽

Diabetic Rats ◽

Oxidized Glutathione ◽

Hepatic Glutathione ◽

Reduced And Oxidized Glutathione

Rats fed a galactose-rich diet have been used for several years as a model for diabetes to study, particularly in the eye, the effects of excess blood hexoses. This study sought to determine the utility of galactosemia as a model for oxidative stress in extraocular tissues by examining biomarkers of oxidative stress in galactose-fed rats and experimentally-induced diabetic rats. Sprague-Dawley rats were divided into four groups: experimental control; streptozotocin-induced diabetic; insulin-treated diabetic; and galactose-fed. The rats were maintained on these regimens for 30 days, at which point the activities of catalase, glutathione peroxidase, glutathione reductase, and superoxide dismutase, as well as levels of lipid peroxidation and reduced and oxidized glutathione were determined in heart, liver, and kidney. This study indicates that while there are some similarities between galactosemic and diabetic rats in these measured indices of oxidative stress (hepatic catalase activity levels and hepatic and renal levels of oxidized glutathione in both diabetic and galactosemic rats were significantly decreased when compared to normal), overall the galactosemic rat model is not closely parallel to the diabetic rat model in extra-ocular tissues. In addition, several effects of diabetes (increased hepatic glutathione peroxidase activity, increased superoxide dismutase activity in kidney and heart, decreased renal and increased cardiac catalase activity) were not mimicked in galactosemic rats, and glutathione concentration in both liver and heart was affected in opposite ways in diabetic rats and galactose- fed rats. Insulin treatment reversed/prevented the activity changes in renal and cardiac superoxide dismutase, renal and cardiac catalase, and hepatic glutathione peroxidase as well as the hepatic changes in lipid peroxidation and reduced and oxidized glutathione, and the increase in cardiac glutathione. Thus, prudence should be exercised in the use of experimentally galactosemic rats as a model for diabetes until the correspondence of the models has been more fully characterized.

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