Role of platelet gel embedded within gelatin scaffold on healing of experimentally induced critical-sized radial bone defects in rats

Purpose: The aim of the present study is to evaluate the influence and efficacy of autologous platelets on bone regeneration in a rabbit defects model. Materials and Methods: A total of 12 critical size tibial defects were produced in six New Zealand rabbits: A total of six defects were filled with autologous platelet gel (APG) and six defects were maintained as untreated controls. No membranes were used to cover the bone osteotomies. The histology and histomorphometry were performed at four weeks on retrieved samples of both groups. Results: No complications were reported in any of the animals nor for the defects produced. A significantly higher lamellar and woven bone percentage was reported for the APG group with a lower level of marrow spaces (p < 0.05). Evidence of newly formed bone was found in the superficial portion of the bone defect of APG samples where no aspects of bone resorption were observed. Conclusions: The evidence of the present research revealed that APG increases new bone formation restricted to the cortical portion and induces more rapid healing in rabbit bone defects than in untreated defects.

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Experimental Amyloidosis Induced by Immune Complex

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100066978 ◽

1971 ◽

Vol 29 ◽

pp. 582-583

Author(s):

A. Kawaoi

Keyword(s):

Immune Complex ◽

Systemic Amyloidosis ◽

Human Diseases ◽

Experimental Amyloidosis ◽

Freund’S Complete Adjuvant ◽

Freund's Complete Adjuvant ◽

Immunological Approach ◽

Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

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Role of L-carnitine treated Mesenchymal stem cells on histological changes in spleen of experimentally induced diabetic rats and the active role of Nrf2 signaling

Egyptian Journal of Histology ◽

10.21608/ejh.2020.34159.1323 ◽

2020 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

Eman Mohamed ◽

Ahmed Reda ◽

Heba Elnegris

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Active Role ◽

Diabetic Rats ◽

Histological Changes ◽

Experimentally Induced

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EXPRESS: The Effects of Experimentally Induced Emotions on Revising Common Vaccine Misconceptions

Quarterly Journal of Experimental Psychology ◽

10.1177/17470218211017840 ◽

2021 ◽

pp. 174702182110178

Author(s):

Greg Trevors ◽

Catherine Bohn-Gettler ◽

Panayiota Kendeou

Keyword(s):

Cognitive Processes ◽

Positive Emotions ◽

Educational Practice ◽

Empirical Knowledge ◽

Emotion Induction ◽

Correct Information ◽

Knowledge Revision ◽

Refutation Texts ◽

Experimentally Induced

Knowledge revision is the process of updating incorrect prior knowledge in light of new, correct information. Although theoretical and empirical knowledge has advanced regarding the cognitive processes involved in revision, less is known about the role of emotions, which have shown inconsistent relations with key revision processes. The present study examined the effects of experimentally induced emotions on online and offline knowledge revision of vaccination misconceptions. Before reading refutation and non-refutation texts, 96 individuals received either a positive, negative, or no emotion induction. Findings showed that negative emotions, more than positive emotions, resulted in enhanced knowledge revision as indicated by greater ease of integrating correct information during reading and higher comprehension test scores after reading. Findings are discussed with respect to contemporary frameworks of knowledge revision and emotion in reading comprehension and implications for educational practice.

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