scholarly journals Progress in understanding inflammatory and autoimmune diseases of the central nervous system

2009 ◽  
Vol 31 (4) ◽  
pp. 437-438 ◽  
Author(s):  
Reinhard Hohlfeld ◽  
Ludwig Kappos
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
The Central Nervous System

scholarly journals Expanding Role of T Cells in Human Autoimmune Diseases of the Central Nervous System

2017 ◽  
Vol 8 ◽  
Author(s):  
Deepti Pilli ◽  
Alicia Zou ◽  
Fiona Tea ◽  
Russell C. Dale ◽  
Fabienne Brilot
Keyword(s):  
Central Nervous System ◽  
T Cells ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
The Central Nervous System

Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseases

2006 ◽  
Vol 111 (3) ◽  
pp. 555-566 ◽  
Author(s):  
Enrico Pedemonte ◽  
Gianluigi Mancardi ◽  
Debora Giunti ◽  
Anna Corcione ◽  
Federica Benvenuto ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Immune Response ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
Adaptive Immune Response ◽  
Adaptive Immune ◽  
The Central Nervous System

scholarly journals Local nitric oxide production in viral and autoimmune diseases of the central nervous system.

1995 ◽  
Vol 92 (12) ◽  
pp. 5312-5316 ◽  
Author(s):  
D. C. Hooper ◽  
S. T. Ohnishi ◽  
R. Kean ◽  
Y. Numagami ◽  
B. Dietzschold ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Central Nervous System ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
Nitric Oxide Production ◽  
Oxide Production ◽  
The Central Nervous System

scholarly journals Charles E. Egwuagu: Going with the flow

2020 ◽  
Vol 217 (11) ◽  
Author(s):  
Stephanie Houston
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
National Institutes Of Health ◽  
Molecular Immunology ◽  
The Central Nervous System

Charles E. Egwuagu is an epidemiologist/immunologist and chief of the Molecular Immunology Section at the National Eye Institute, National Institutes of Health, Bethesda, MD. His laboratory is focused on understanding the role played by lymphocytes in autoimmune diseases of the central nervous system. I chatted with Charles about his career so far.

Role of CD8 T-Cell-Mediated Autoimmune Diseases of the Central Nervous System

2010 ◽  
Vol 30 (4) ◽  
pp. 311-326 ◽  
Author(s):  
Martina Deckert ◽  
Monica Sanchez-Ruiz ◽  
Anna Brunn ◽  
Dirk Schluter
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
T Cell ◽  
Autoimmune Diseases ◽  
Cd8 T Cell ◽  
The Central Nervous System

scholarly journals CD226 Gly307Ser Association With Neuromyelitis Optica in Southern Han Chinese

2012 ◽  
Vol 39 (4) ◽  
pp. 488-490 ◽  
Author(s):  
Chao Liu ◽  
Guansan Wang ◽  
Hong Liu ◽  
Yue Li ◽  
Jin Li ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Autoimmune Diseases ◽  
Neuromyelitis Optica ◽  
Han Chinese ◽  
Relapsing Remitting ◽  
The Central Nervous System ◽  
Relapsing Remitting Multiple Sclerosis

Background:Neuromyelitis optica (NMO) and multiple sclerosis (MS) are autoimmune diseases of the central nervous system with complex pathogeneses. NMO was once considered to be a severe variant of MS. There has been more evidence that a non-synonymous exchange (rs763361/Gly307Ser) in the gene for CD226 is linked to several autoimmune diseases including multiple sclerosis (MS). However, no studies have investigated the role of rs763361 in the pathogenesis of NMO.Objectives:The goal of our study is to evaluate the role of CD226 Gly307Ser in neuromyelitis optica (NMO) in Southern Han Chinese.Methods:Eight-nine NMO patients, 93 relapsing-remitting multiple sclerosis (RRMS) patients, and 122 controls (CTLs) were enrolled. The rs763361 alleles of the subjects were determined by sequencing-based typing.Results:The results strongly support that the TT genotypes are associated with NMO but are not significantly correlated with susceptibility for MS.Conclusions:CD226 Gly307Ser may correlate with risk of NMO in Southern Han Chinese.

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