Prognostic CT and MR imaging features in patients with untreated extranodal non-Hodgkin lymphoma of the head and neck region

2015 ◽  
Vol 25 (10) ◽  
pp. 3035-3042 ◽  
Author(s):  
Cuiping Zhou ◽  
Xiaohui Duan ◽  
Bowen Lan ◽  
Junjie Liao ◽  
Jun Shen
Keyword(s):  
Mr Imaging ◽  
Head And Neck ◽  
Hodgkin Lymphoma ◽  
Neck Region ◽  
Imaging Features ◽  
Head And Neck Region ◽  
Non Hodgkin Lymphoma

scholarly journals Varied Presentations of Non-Hodgkin Lymphoma in Head and Neck Region

2020 ◽  
Vol 28 (1) ◽  
pp. 30-36
Author(s):  
Chiranjib Das ◽  
Pritam Chatterjee
Keyword(s):  
Head And Neck ◽  
Hodgkin Lymphoma ◽  
Nk Cell ◽  
Tertiary Care ◽  
Cervical Lymphadenopathy ◽  
Neck Region ◽  
Care Hospital ◽  
Head And Neck Region ◽  
Non Hodgkin Lymphoma ◽  
A Prospective Study

Introduction Majority of lymphomas involving the head and neck are Non-Hodgkin lymphoma (NHL). Most of them present as cervical lymphadenopathy. The objectives of this study are to present the problems encountered in the diagnosis of extra-nodal NHL in head and neck region and show the importance of thorough clinical examination and proper investigation. Materials and Methods A prospective study was done in the department of ENT in a tertiary care hospital of West Bengal from July 2015 to June 2018. Patients diagnosed as NHL on the basis of histopathology and immunohistochemistry were included in this study. Patients who were lost in follow up were excluded from the study. Patients were treated with chemotherapy and radiotherapy by Oncologist. All patients were followed up routinely both by Otorhinolaryngologist and Oncologist.     Results There were 26 male and 11 female patients in this study. Patients were between 22 years to 76 years of age with highest incidence in 6th decade of life. Patients presented with only cervical lymphadenopathy; asymmetrical tonsillar enlargement with cervical lymphadenopathy; unilateral tonsillar enlargement only; huge inta-oral mass with stridor; parotid gland swelling; thyroid swelling with multiple cervical lymphadenopathy; epistaxis, palatal ulcer and cheek swelling; severe trismus with inconspicuous retro-mandibular mass. Majority of patients did well with chemoradiotherapy. Two patients succumbed to death, one with huge intra-oral NHL and another with nasal T/NK-cell lymphoma.  Conclusion Good knowledge of the clinical characteristics of extra-nodal NHL and the methods to establish the diagnosis are essential for a correct and timely therapy of the disease.

Clinical manifestation of malignant lymphomas of the head and neck region

2017 ◽  
Vol 71 (6) ◽  
pp. 14-21 ◽  
Author(s):  
Katarzyna Bojanowska-Poźniak ◽  
Wioletta Pietruszewska
Keyword(s):  
Head And Neck ◽  
Hodgkin Lymphoma ◽  
Young Patients ◽  
Neck Region ◽  
Lymphoid Cells ◽  
Diagnostic Process ◽  
Malignant Neoplasms ◽  
Malignant Lymphomas ◽  
Head And Neck Region ◽  
Medical University

Introduction: Malignant lymphoma (ML) is a neoplasm caused by clonal expansion of undifferentiated B, T and NK-lymphoid cells. WHO classification divides lymphomas into two main types, i.e. Hodgkin lymphoma (HL), and non-Hodgkin lymphoma (NHL), with numerous subtypes. The majority of MLs are localized in lymph nodes, but extranodal locations are also possible. MLs represent approximately 3-5% of all malignant neoplasms in Poland, but their incidence has been increasing in recent years, especially in young patients. The objective of the study was to evaluate clinical manifestations and diagnostic process in patients with malignant lymphomas of the head and neck region as diagnosed in the Department of Otorhinolaryngology of the Medical University of Lodz in years 2013-2017. Material and method: 30 patients diagnosed with malignant lymphomas of the head and neck region at the Departbadament of Otorhinolaryngology of the Medical University of Lodz in 2013-2017. Results: The study group consisted of 8 cases of nodal lymphomas and 22 cases of extranodal lymphomas. In 29 cases B-cell lymphomas were diagnosed. The most common symptoms included lymphadenopathy or neck tumor. Other symptoms were associated with the location of tumors in particular body organs. The diagnosis was based on histopathological examination of biopsy (needle or surgical) samples. Conclusion: Malignant lymphomas should be taken into account during differential diagnosis of the tumor or lymphadenopathy of the neck. The diagnosis is difficult because of the nonspecificity of symptoms and the need for interdisciplinary cooperation of many specialists.

scholarly journals Imaging Features of Postradiotherapy Changes in Head and Neck Cancers

2021 ◽  
Author(s):  
Anisha Gehani ◽  
Saugata Sen ◽  
Sanjoy Chatterjee ◽  
Sumit Mukhopadhyay
Keyword(s):  
Head And Neck ◽  
Imaging Techniques ◽  
Neck Region ◽  
Head And Neck Cancers ◽  
Imaging Features ◽  
Recurrent Tumor ◽  
Cross Sectional ◽  
Head And Neck Region ◽  
Pictorial Essay ◽  
Cross Sectional Imaging

AbstractRadiation therapy is the mainstay in the treatment of head and neck cancers, in addition to surgery and chemotherapy. Expected radiotherapy changes evolving over time may be confused with recurrent tumor. Conversely, even residual or recurrent tumor in the setting of postradiotherapy changes may be difficult to identify clinically or even by radiological imaging. Therefore, it is important to be familiar with the temporal evolution of these changes. The purpose of this pictorial essay is thus to illustrate distinctly the expected radiotherapy changes and radiotherapy-related complications in the head and neck region and to differentiate them from tumor recurrence on routine cross-sectional imaging techniques (computed tomography and magnetic resonance imaging).

Vascular Mass Lesions and Hypervascular Tumors in the Head and Neck

1995 ◽  
Vol 36 (2) ◽  
pp. 136-141 ◽  
Author(s):  
F. Aspestrand ◽  
A. Kolbenstvedt
Keyword(s):  
Mr Imaging ◽  
Head And Neck ◽  
Neck Region ◽  
Head And Neck Region ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Cavernous Hemangiomas ◽  
Hypervascular Tumors ◽  
Mass Lesions

A retrospective analysis of the findings at contrast-enhanced CT, MR imaging and angiography in 24 patients with vascular mass lesions and 11 patients with hypervascular tumors in the head and neck region was undertaken. We attempted to find criteria at CT and MR imaging that could aid in differentiating between different lesion categories. Parameters such as contrast enhancement at CT, signal intensities at MR imaging, phleboliths and peritumoral hypervascularity were correlated to clinical presentation, biopsies and angiography. MR imaging was superior to CT and far better than angiography in delineating cavernous hemangiomas. Contrast-enhanced CT may better differentiate between cavernous and capillary hemangiomas than MR. MR imaging clearly differentiated cavernous hemangiomas from hypervascular tumors, but was, like CT, inadequate for distinguishing between capillary hemangiomas and hypervascular tumors. Lymphangiomas and cavernous hemangiomas had similar appearances at CT and MR imaging.

DIFFUSION-WEIGHTED MR IMAGING APPLICATION IN EVALUATION OF RESPONSE TO TREATMENT OF HEAD AND NECK REGION CANCER

2011 ◽  
Vol 98 ◽  
pp. S37
Author(s):  
M. Jedrzejewska ◽  
G. Gabriela Stasik-Pres ◽  
B. Hejduk ◽  
B. Bobek-Billewicz ◽  
K. Skladowski ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Head And Neck ◽  
Neck Region ◽  
Response To Treatment ◽  
Head And Neck Region ◽  
Diffusion Weighted ◽  
Imaging Application

scholarly journals Hubungan kadar CA 125 dengan karakteristik klinis Diffuse Large B cell Lymphoma

2019 ◽  
Vol 49 (1) ◽  
pp. 67
Author(s):  
Agung Dinasti Permana ◽  
Igor Hutabarat ◽  
Thaufiq Boesoirie ◽  
Bethy S. Hernowo ◽  
Rovina Ruslami
Keyword(s):  
B Cell ◽  
Head And Neck ◽  
Cell Lymphoma ◽  
Neck Region ◽  
B Cell Lymphoma ◽  
Ca 125 ◽  
Head And Neck Region ◽  
Non Hodgkin Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Latar belakang: Kadar serum CA 125 telah diketahui mengalami peningkatan pada kasus limfoma non Hodgkin. Kegunaannya dalam menentukan prognosis, tingkat keparahan penyakit, dan follow up pasca terapi limfoma non Hodgkin telah banyak diteliti dan masih didapatkan hasil yang bervariasi. Saat ini belum diketahui mengenai kadar serum CA 125 pada kasus diffuse large B cell lymphoma (DLBCL) yang bermanifestasi di regio kepala dan leher. Tujuan: Mengetahui hubungan kadar serum CA 125 dengan karakteristik klinis pada kasus DLBCL regio kepala dan leher. Metode: Penelitian ini merupakan penelitian potong lintang yang melibatkan 31 subjek penelitian dengan diagnosis DLBCL regio kepala dan leher. Dilakukan pencatatan karakteristik klinis dan penentuan kadar serum CA 125 dengan pemeriksaan Immunoasai dan kemudian dilakukan analisis statistik untuk menentukan hubungan antar variabel. Hasil: Didapatkan peningkatan kadar serum CA 125 pada stadium lanjut dengan p<0,001. Analisis statistik terhadap kadar serum CA 125 dan Kadar Lactic Dehydrogenase (LDH) menunjukkan hubungan yang signifikan (p=0,018) demikian juga hubungannya dengan skorEastern Cooperative Oncology Group (ECOG) dengan nilai p=0,001. Pada penelitian ini tidak terdapat hubungan yang bermakna antara kadar serum CA 125 dengan skor Prognostic International Index (IPI). Kesimpulan: Kadar serum CA 125 berhubungan bermakna dengan stadium klinis, kadar LDH dan Skor ECOG pada DLBCL yang bermanifestasi di regio kepala dan leher. Dengan demikian CA 125 dapat digunakan sebagai marker untuk memprediksi prognosis dan mendekati stadium lanjut kasus limfoma non Hodgkin. Background: Serum CA 125 level has been known to increase in Non-Hodgkin Lymphoma cases.Many studies had elaborately researched the prognosis, disease severity and the follow up of Non Hodgkin Lymphoma cases using CA 125, yet the results had been varied. Up to now, serum CA 125 levels in cases of diffuse large B cell lymphoma (DLBCL) which manifest in the head and neck region, is still unclear. Purpose: To find out the correlation of serum CA 125 levels with clinical manifestations of DLBCL cases in the head and neck region. Method: A cross-sectional study involving 31 subjects diagnosed with DLBCL in the head and neck region. The clinical manifestations were recorded and serum CA 125 levels were obtained by Immunoassay examination. Statistical analysis was performed to determine the correlation between variables. Results: An increase in serum CA 125 levels at an advanced stage with p <0.001. The statistical result of CA 125 serum levels and LDH levels showed a significant correlation (p=0.018), as well as its significant correlation with the Eastern Cooperative Oncology Group (ECOG) score, with p=0.001. In this study there was no significant correlation between CA 125 serum levels and Prognostic International Index (IPI) scores. Conclusion: Serum CA 125 levels were significantly correlated with clinical stage, LDH level and ECOG score of DLBCL which manifested in the head and neck region. Therefore, CA 125 might be used as a marker to predict prognosis and to detect advanced disease in Non-Hodgkin Lymphoma cases.

Sign in / Sign up

Export Citation Format

Share Document