The impact of the International Subarachnoid Aneurysm Treatment Trial (ISAT) on neurosurgical practice

2003 ◽  
Vol 145 (2) ◽  
pp. 97-99 ◽  
Author(s):  
K. W. Lindsay
2021 ◽  
Vol 25 (9) ◽  
pp. 1743-1746
Author(s):  
T.A. Adebisi -Fagbohungbe ◽  
A.S. Kehinde ◽  
O.O. Babatunde ◽  
I.E. Odiaka ◽  
F.A. Abuldulazeez ◽  
...  

The impact of captive rearing of snails (Archachatina marginata) on the bio-accumulation of some heavy metals (HMs) (Fe, Mn, Cu, Pb, Co, Ni, Cd and Cr) in the meat and haemolymph was evaluated in a two treatment trial (snails from the wild, (SW) and captive reared snails, (SC), each comprised of sixty snails of three replicates. Alldata collected (using standard analytical procedures) were subjected to ANOVA and significant means separated by Duncan Multiple Range Test. The trial revealed that the meat of SC had outstanding (P>0.05) Fe (22.30mg/kg) and Mn(4.79mg/kg), with no significant variation for DM, while the haemolymph recorded non-significant (P< 0.05) concentration for (Mn, Pb, Co, Ni, Cd and Cr). Its levels of Fe (3.50mg/kg) and Cu (2.06mg/kg) were however significantly (P>0.05) impacted by captive rearing. Generally the level of Cr in the meat and haemolymph were higher than 0.05mg/kg recommendation by WHO, hence snail meat and haemolymph must be consumed with caution and guidance.


Ophthalmology ◽  
1999 ◽  
Vol 106 (11) ◽  
pp. 2047-2053 ◽  
Author(s):  
Jonathan D Trobe ◽  
Pamela C Sieving ◽  
Kenneth E Guire ◽  
A.Mark Fendrick

2021 ◽  
Vol 11 (17) ◽  
pp. 8082
Author(s):  
Sima Baheri Islami ◽  
Mike Wesolowski ◽  
William Revell ◽  
Xiongbiao Chen

Virtual reality (VR) has the potential to be a powerful tool for the visualization of simulated blood flow in cerebral aneurysms. This paper presents our study aimed at developing the VR visualization of computational fluid dynamics (CFD) simulations of cerebral aneurysms treated with flow-diverting (FD) stents. First, a spherical sidewall aneurysm located at a simplified internal carotid artery was considered for investigating the impact of stent deployment and positioning on the corresponding spatially time-varying blood flow behavior. The three-dimensional unsteady blood flow over a cardiac cycle was simulated numerically using the finite volume method, and the distributions of hemodynamic parameters inside the aneurysm sac, and on its wall, were presented with and without stent cases. Two stent positions, with and without a gap between the artery wall and stent, were considered to show the influence of correct stent position on aneurysm treatment. Second, a straightforward workflow was developed to import, process, and visualize the CFD analysis data in a VR environment by using open-source software with a high resolution. The Unity3D engine was used for displaying the processed animations in a VR environment operated on a head-mounted display (HMD). The refining process of each frame of time-varying CFD data was automated. The animated flow elements rendered in the VR environment were velocity vectors, velocity contours, streamlines, particle traces, and point clouds. CFD results showed that proper stenting facilitates thrombosis and occlusion of the aneurysm by modification of the flow patterns, which leads to lower inflow jet velocities into the aneurysm, longer turnover time, lower aneurysm-averaged kinetic energy, and lower wall shear stress. Additionally, the results indicated that a gap between the stent and the parent artery may lead to undesirable hemodynamic alterations. The VR visualization illustrated that the recognition of the potential in danger regions of aneurysms and the evaluation of the performance of FD stents in aneurysm treatment can be conducted without the need for several slices through the parent artery and aneurysm, as is required for traditional postprocessing methods. Through VR visualization, the details of the simulation results become readily available by navigating in the 3D animated flow elements using a high-degree-of-freedom headset.


2007 ◽  
Vol 41 (1) ◽  
pp. 62-65 ◽  
Author(s):  
Peter R. Joyce ◽  
Samantha A.H. Williamson ◽  
Janice M. McKenzie ◽  
Christopher M.A. Frampton ◽  
Suzanne E. Luty ◽  
...  

Objective: To evaluate the impact of childhood abuse and parental bonding on cortisol levels in depressed adults. Methods: Mean afternoon cortisol levels were measured in 192 depressed adult patients at the beginning of a treatment trial. Childhood experiences of physical and sexual abuse were ascertained by interview, and perceived parenting by self-report. Results: Maternal affectionless control, childhood sexual and physical abuse were all associated with cortisol levels. Conclusion: Childhood experiences, especially maternal affectionless control, appear to be related to hypothalamic pituitary adrenal axis function in depressed adults.


Stroke ◽  
2022 ◽  
Author(s):  
Angelica M. Fuentes ◽  
Laura Stone McGuire ◽  
Sepideh Amin-Hanjani

Sex differences in cerebral aneurysm occurrence and characteristics have been well described. Although sex differences in outcomes following ischemic stroke have been identified, the effect of sex on outcomes following hemorrhagic stroke, and in particular, aneurysm treatment has been less studied. We describe the current state of knowledge regarding the impact of sex on treatment and outcomes of cerebral aneurysms. Although prior studies suggest that aneurysm prevalence and progression may be related to sex, we did not find clear evidence that outcomes following subarachnoid hemorrhage vary based on sex. Last, we identify areas for future research that could enhance understanding of the role sex plays in this context.


1962 ◽  
Vol 14 ◽  
pp. 415-418
Author(s):  
K. P. Stanyukovich ◽  
V. A. Bronshten

The phenomena accompanying the impact of large meteorites on the surface of the Moon or of the Earth can be examined on the basis of the theory of explosive phenomena if we assume that, instead of an exploding meteorite moving inside the rock, we have an explosive charge (equivalent in energy), situated at a certain distance under the surface.


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