scholarly journals Inclusion of a pH-responsive amino acid-based amphiphile in methotrexate-loaded chitosan nanoparticles as a delivery strategy in cancer therapy

Amino Acids ◽  
2015 ◽  
Vol 48 (1) ◽  
pp. 157-168 ◽  
Author(s):  
Daniele Rubert Nogueira ◽  
Laís E. Scheeren ◽  
Letícia B. Macedo ◽  
Ana Isa P. Marcolino ◽  
M. Pilar Vinardell ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cancer Therapy ◽  
Chitosan Nanoparticles ◽  
Ph Responsive ◽  
Delivery Strategy

Block copolymer [(l-GluA-5-BE)-b-(l-AspA-4-BE)]-based nanoflower capsules with thermosensitive morphology and pH-responsive drug release for cancer therapy

2020 ◽  
Vol 8 (40) ◽  
pp. 9258-9268
Author(s):  
Chander Amgoth ◽  
Shuai Chen ◽  
Tirupathi Malavath ◽  
Guping Tang
Keyword(s):  
Amino Acid ◽  
Block Copolymer ◽  
Cancer Therapy ◽  
Drug Release ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Benzyl Ester ◽  
Ph Responsive

Herein, the synthesis of an amino-acid-based di-block copolymer (di-BCP) in-between an l-glutamic acid-5-benzyl ester and L-aspartic acid-4-benzyl ester [(l-GluA-5-BE)-b-(l-AspA-4-BE)] has been reported.

Folate-Targeted Multifunctional Amino Acid-Chitosan Nanoparticles for Improved Cancer Therapy

2014 ◽  
Vol 32 (2) ◽  
pp. 562-577 ◽  
Author(s):  
Vítor M. Gaspar ◽  
Elisabete C. Costa ◽  
João A. Queiroz ◽  
Chantal Pichon ◽  
Fani Sousa ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cancer Therapy ◽  
Chitosan Nanoparticles

Mitochondrial alkaline pH-responsive drug release mediated by Celastrol loaded glycolipid-like micelles for cancer therapy

Biomaterials ◽  
2018 ◽  
Vol 154 ◽  
pp. 169-181 ◽  
Author(s):  
Yanan Tan ◽  
Yun Zhu ◽  
Yue Zhao ◽  
Lijuan Wen ◽  
Tingting Meng ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Alkaline Ph ◽  
Ph Responsive

Pharmacologic approaches to amino acid depletion for cancer therapy

2021 ◽  
Author(s):  
Carly S. Wilder ◽  
Zhao Chen ◽  
John DiGiovanni
Keyword(s):  
Amino Acid ◽  
Cancer Therapy ◽  
Amino Acid Depletion

In vivo metabolizable branched poly(ester amide) based on inositol and amino acids as drug nanocarrier for cancer therapy

2021 ◽  
Author(s):  
Jun Wu ◽  
Qi-Juan Yuan ◽  
Li Wang ◽  
Jun Huang ◽  
Wei Zhao
Keyword(s):  
Mechanical Property ◽  
Amino Acids ◽  
Amino Acid ◽  
Cancer Therapy ◽  
Biomedical Applications ◽  
Bioactive Components ◽  
Good Biocompatibility

Amino acid-based poly(ester amide) (PEA) has been utilized for various biomedical applications for its tunable mechanical property, good biocompatibility, and biodegradability. However, bioactive components have rarely been incorporated into the...

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