Clinical presentation of patients with oral squamous cell carcinoma when first seen by dentists or physicians in a teaching hospital in Brazil

2003 ◽  
Vol 7 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Paulo Rogério de Faria ◽  
Sérgio Vitorino Cardoso ◽  
Sérgio de A. Nishioka ◽  
Sindeval José Silva ◽  
Adriano Mota Loyola
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Teaching Hospital ◽  
Squamous Cell ◽  
Clinical Presentation

scholarly journals Difference in Clinical Presentation and Their Significance in Oral Squamous Cell Carcinoma – a Retrospective Analysis

2022 ◽  
Author(s):  
Jeyashanth Riju ◽  
Amit Jiwan Tirkey ◽  
Malavika Babu ◽  
Ronald Anto ◽  
Amey Madhav Baitule ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Perineural Invasion ◽  
Clinical Presentation ◽  
Tongue Cancer ◽  
Clinical History ◽  
Depth Of Invasion ◽  
Advanced Stage

Abstract Oral squamous cell carcinoma(OSCC) involving tongue and buccoalveolar complex(BAC) behaves differently. Clinical features of the two subsites and their influence on pathological factors remain least analysed. Patients are divided into two groups i.e, tongue cancer and BAC cancer group, and various clinical parameters were compared. Among 474 patients 232 had tongue cancer and 242 had BAC cancer. 30% of patients with OSCC were asymptomatic at presentation except for the ulcer. Compared to tongue cancers, lesions confined to BAC presents at an advanced stage(p=0.006). Multivariate analysis showed that dysphagia in tongue cancer(p=0.020) and external swelling or lesion in BAC cancers(p=0.002) were significant predictors of an advanced stage of disease. On histopathology perineural invasion was significantly associated tongue(p=0.008) and BAC cancers(P=0.015). Among tongue cancers, those with pain and referred otalgia had a statistically significantly high depth of invasion(DOI), compared to those without pain (DOI – no pain 6.9mm, pain 9.9mm and referred otalgia 11.4mm). There is a delay in clinical presentation of OSCC. Among tongue cancers, clinical history of pain was significantly associated with depth of invasion and perineural invasion, the significance of which needs to be prospectively analysed. Clinical history in OSCC can be used as predicting factors for various pathological characters, which is subsite specific.

scholarly journals Human papilloma virus prevalence and its correlation with clinical presentation and histological grading in oral squamous cell carcinoma.

2021 ◽  
Vol 28 (08) ◽  
pp. 1067-1075
Author(s):  
Fahad Ahmed ◽  
◽  
Hassan Shahid ◽  
Salman Shafique ◽  
Aswad Ahmed ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Presentation ◽  
Oral Surgery ◽  
Histological Grading ◽  
Papilloma Virus ◽  
Submucous Fibrosis

Objectives: The objectives of this study were to determine the prevalence of Human Papilloma virus 16 in patients with oral squamous cell carcinoma presenting at Isra University Hospital and to correlate the existence of Human Papilloma virus 16 in squamous cell carcinoma with clinical presentation, habits and histological grading. Study Design: Interventional Study. Setting: Department of Oral Surgery, Isra Dental College Hospital. Period: July 2017 to December 2017. Material & Methods: A sample of 60 patients presenting were selected by non-probability purposive sampling. Patients reporting to Isra Dental College, Oral Surgery OPD Isra University during the study period with clinical suspicion of Oral Squamous Cell Carcinoma were included. Results: Age category was from 20 till 60+ years of age whereas age group of 40-49 (36.7%) was the most frequent age in the study population followed by 30-39 (30%) years and 50-59 (23.3%) years of age respectively. The mean and standard deviation was 43.35 ± 10.156 respectively. Maximum numbers of people were seen to have more than one habit i.e. they were using guthka with smoking or areca nut with guthka and smoking etc. areca nut, cigarette smoking and guthka were among the others most used. The mean was 6.32 with standard deviation of 2.954. Most of the patients had submucous fibrosis on the right side of buccal vestibule 24 (40%) and 22 (36.7%) had submucous fibrosis on the left side of buccal vestibule. 56 (93.3%) of the patients had well differentiated squamous cell carcinoma whereas 4 (6.7%) has moderately differentiated squamous cell carcinoma. No patients were seen to have poorly differentiated squamous cell carcinoma. Conclusion: In conclusion, the Prevalence of HPV 16 in our study was found to be 11.7%. There was no association between habits and histological grading with Human Papillomavirus 16 in patient with oral squamous cell carcinoma. But there was association between HPV16 and clinical presentation of OSCC because of p-value (.015) which was significant.

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