scholarly journals Triptans in clinical practice: the basic scientist’s point of view

2001 ◽  
Vol 2 (S1) ◽  
pp. s93-s96
Author(s):  
M. Gabriella Buzzi
2021 ◽  
Vol 93 (1) ◽  
pp. 92-100
Author(s):  
Andrea B. Galosi ◽  
Erika Palagonia ◽  
Simone Scarcella ◽  
Alessia Cimadamore ◽  
Vito Lacetera ◽  
...  

Reasons why significant prostate cancer is still missed in early stage were investigated at the 22nd National SIEUN (Italian Society of integrated diagnostic in Urology, Andrology, Nephrology) congress took place from 30th November to 1st December 2020, in virtual modality. Even if multiparametric magnetic resonance (MR) has been introduced in the clinical practice several, limitations are emerging in patient with regular digital rectal examination (DRE) and serum prostate specific antigen (PSA) levels approaching the normal limits. The present paper summarizes highlights observed in those cases where significant prostate cancer may be missed by PSA or imaging and DRE. The issue of multidisciplinary interest had been subdivided and deepened under four main topics: biochemical, clinical, pathological and radiological point of view with a focus on PI-RADS 3 lesions.


Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 286-291 ◽  
Author(s):  
Alessia Ferrarese ◽  
Giada Pozzi ◽  
Felice Borghi ◽  
Alessandra Marano ◽  
Paola Delbon ◽  
...  

AbstractRobotic surgery (RS) technology has undergone rapid growth in the surgical field since its approval. In clinical practice, failure of robotic procedures mainly results from a surgeon’s inability or to a device malfunction. We reviewed the literature to estimate the impact of this second circumstance in RS and its consequent legal implications. According to data from the literature, device malfunction is rare. We believe it is necessary to complement surgical training with a technical understanding of RS devices.


2014 ◽  
Vol 44 (S1) ◽  
pp. 324-324
Author(s):  
L. Ples ◽  
R. Sima ◽  
E. Mihaly ◽  
E. Tarta ◽  
A. Ghergus ◽  
...  

2019 ◽  
pp. 22-31
Author(s):  
D. I. Trukhan ◽  
I. A. Viktorova

Gastroesophageal reflux disease (GERD) in terms of prevalence ranks first among gastroenterological diseases. A large number of works on the diagnosis and treatment of GERD, forms the point of view that about GERD «everything is long and well known.» However, in real clinical practice, for various reasons, possible «pitfalls, reefs and shallows» are not taken into account, the underestimation of which can introduce certain difficulties in the diagnosis and treatment. This review discusses the most significant aspects of the diagnosis and treatment of GERD in real clinical practice by a general practitioner and general practitioner. Currently, proton pump inhibitors are the main drugs for the treatment of GERD and other acid-dependent diseases. The results of numerous foreign and Russian studies indicate the effectiveness and safety of pantoprazole in the treatment of GERD, especially in multimorbid patients due to the lower potential of drug interactions. The presence on the Russian pharmaceutical market of two forms of release of the generic drug pantoprazole Panum® increases the availability of effective and safe therapy for GERD and other acid-dependent diseases.


2019 ◽  
pp. 50-58
Author(s):  
D. I. Trukhan ◽  
E. L. Davydov

An urgent public health problem is the optimization of drug therapy in patients with chronic heart failure.A large number of works devoted to the treatment of chronic heart failure form the point of view that about the treatment of chronic heart failure «all is well known for a long time.» However, in real clinical practice, especially at the stage of primary health care, for various reasons, possible pitfalls, reefs and shallows are not taken into account, the underestimation of which can introduce certain difficulties and cause the treatment of patients with chronic heart failure to be ineffective.The review article examined a number of important aspects of the treatment of chronic heart failure, which, for various reasons, are underestimated in the supervision of patients. First of all, this refers to antagonists of mineralocorticoid receptors, in particular to spironolactone, and an inhibitor of If - channels of the sinus node ivabradine.The results of foreign and Russian studies, modern recommendations for the supervision of patients with chronic heart failure, indicate that the presence of spironolactone and ivabradine in the arsenal of a practical doctor allows optimizing drug therapy in patients with chronic heart failure and increasing its effectiveness.


2020 ◽  
Vol 48 (6) ◽  
pp. 349-363
Author(s):  
D. S. Bordin ◽  
Yu. A. Kucheryavyy ◽  
M. A. Kiryukova

The discoveries in molecular genetics and breakthrough visualization techniques in the last 20 years have changed our understanding of the pancreatitis causes and biomarkers, expanded our knowledge on the pathophysiology of the disease, and promoted the development of new additional conservative treatments. From the practical perspective, the physician's comprehension of the etiology is of particular importance. It is for this reason that the activities to elaborate an etiology-based classification of pancreatitis have been already started since long ago. The first internationally acknowledged system was TIGAR-O checklist, introduced in 2001. Being innovative at the time, it structured our understanding of the etiology of chronic pancreatitis. The revised version (version 2) was published in 2019 and is less known to the Russian medical community, although from the authors' point of view, it has been substantially extended and structured to be maximally convenient and useful for physicians in routine medical practice. The review presents key provisions of the TIGAR-O, version 2 and recommendations for its adaption to the Russian clinical setting.


Author(s):  
Guido Coggi

The years during which Paolo Mantegazza served as Dean of the Medical Faculty, the Country was involved in a considerably large social turmoil, under the pressure of the so called student revolution, which was spreading through Europe. Such a movement, albeit very often out of control (with dangerous deviations), still was, in its basic and best aspects, the expression of an urgent need for innovation and social change. Mantegazza, who was a very qualified scientist in Pharmacology, perceived by intuition the need for a controlled change in the style and action of his office, and used a “gentle leadership” to carry on consistent innovations in the traditional “academic” policy of the Faculty. His major achievement was twofold: first, he was able to expand the Faculty into city hospitals other than the traditional Main Central University Hospital, thus allowing students to perform clinical practice in a new environment, more patient oriented than the classical one; second, this expansion offered teachers and researchers the opportunity to practice a less formal teaching, paying more attention, both from a clinical, scientific and teaching point of view, to the complexity of the patient and his/her social and personal context, with relevant consequences on the educational approach and to teacher-students relationships.


1994 ◽  
Vol 10 (1) ◽  
pp. 37-41 ◽  
Author(s):  
François Loew ◽  
Charles-Henri Rapin

Although evaluation scales for quality of life (QOL) represent considerable progress in medicine, clinical experience shows striking discrepancies between QOL as evaluated by caregivers and QOL from the patient's point of view. Such paradoxes of QOL are analyzed and discussed. Autonomy is universally advocated but may be denied, especially in the hospital setting, where caregivers, family members, and doctors act as a pressure group. Circumstances that deepen the contradictions in QOL assessment include (a) a high degree of patient dependence, (b) a professional judgement that a patient is incompetent (c) professional values being placed over a patient's values, (d) a multidisciplinary team acting as a pressure group, (e) a lack of effective communication with the patient, and (f) a determination to minimize the symptoms at evaluation. QOL is multidimensional, complex, difficult to measure in clinical practice, and sometimes paradoxical.


2018 ◽  
Vol 47 (1-3) ◽  
pp. 37-44 ◽  
Author(s):  
Carlo Alfieri ◽  
Anna Regalia ◽  
Francesca Zanoni ◽  
Simone Vettoretti ◽  
Mario Cozzolino ◽  
...  

Secondary hyperparathyroidism (SHPT) is a frequent condition in the presence of chronic kidney disease (CKD). In CKD patients, SHPT is reported to increase both morbidity and mortality, especially cardiovascular. The difficulty in the treatment of SHPT in clinical practice is frequently encountered from a not always adequate conduct of the clinicians and a common non-compliance to the therapy of CKD patients. In this review, the greatest difficulties from clinicians and CKD-patients’ point of view in the treatment of SHPT will be addressed, with particular attention to those related to dialysis features, nutritional habits, and medical therapy.


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