Hyperpolarized 3He lung ventilation imaging with B 1-inhomogeneity correction in a single breath-hold scan

Author(s):  
G. W. Miller ◽  
T. A. Altes ◽  
J. R. Brookeman ◽  
E. E. de Lange ◽  
J. P. Mugler III
1993 ◽  
Vol 3 (4) ◽  
pp. 611-616 ◽  
Author(s):  
Thomas K. F. Foo ◽  
James R. Macfall ◽  
H. Dirk Sostman ◽  
Cecil E. Hayes

2017 ◽  
Vol 79 (2) ◽  
pp. 815-825 ◽  
Author(s):  
Xiufeng Li ◽  
Edward J. Auerbach ◽  
Pierre-Francois Van de Moortele ◽  
Kamil Ugurbil ◽  
Gregory J. Metzger

Cancers ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 222 ◽  
Author(s):  
Varsha Jain ◽  
Abigail Berman

Radiation therapy is a major treatment modality for management of non-small cell lung cancer. Radiation pneumonitis is a dose limiting toxicity of radiotherapy, affecting its therapeutic ratio. This review presents patient and treatment related factors associated with the development of radiation pneumonitis. Research focusing on reducing the incidence of radiation pneumonitis by using information about lung ventilation, imaging-based biomarkers as well as normal tissue complication models is discussed. Recent advances in our understanding of molecular mechanisms underlying lung injury has led to the development of several targeted interventions, which are also explored in this review.


1975 ◽  
Vol 38 (5) ◽  
pp. 768-773 ◽  
Author(s):  
N. N. Stanley ◽  
M. D. Altose ◽  
S. G. Kelsen ◽  
C. F. Ward ◽  
N. S. Cherniack

Experiments were conducted on human subjects to study the effect of lung inflation during breath holding on respiratory drive. Two series of experiments were performed: the first to examine respiratory drive during a single breath hold, the second designed to examine the sustained effect of lung inflation on subsequent breath holds. The experiments involved breath holding begun either at the end of a normal expiration or after a maximum inspiration. When breath holding was repeated at 10-min intervals, the increase in BHT produced by lung inflation was greater in short breath holds (after CO2 rebreathing) than in long breath holds (after hyperventilation). If breath holds were made in rapid succession, the first breath hold was much longer when made at total lung capacity than at functional residual capacity, but this effect of lung inflation diminished in subsequent breath holds. It is concluded that the inhibitory effect of lung inflation decays during breath holding and is regained remarkably slowly during the period of breathing immediately after breath holding.


2018 ◽  
Vol 31 (6) ◽  
pp. e3923 ◽  
Author(s):  
Yong Chen ◽  
Wei-Ching Lo ◽  
Jesse I. Hamilton ◽  
Kestutis Barkauskas ◽  
Haris Saybasili ◽  
...  

2018 ◽  
Vol 81 (4) ◽  
pp. 2464-2473 ◽  
Author(s):  
L. Mendes Pereira ◽  
T. Wech ◽  
A.M. Weng ◽  
C. Kestler ◽  
S. Veldhoen ◽  
...  

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