Vectors, Hosts, and Control Measures for Zika Virus in the Americas

EcoHealth ◽  
2017 ◽  
Vol 14 (4) ◽  
pp. 821-839 ◽  
Author(s):  
Sarah J. Thompson ◽  
John M. Pearce ◽  
Andrew M. Ramey
Keyword(s):  
Zika Virus ◽  
Control Measures ◽  
And Control

scholarly journals Times to Key Events in the Course of Zika Infection and their Implications for Surveillance: A Systematic Review and Pooled Analysis

2016 ◽  
Author(s):  
Justin Lessler ◽  
Cassandra T. Ott ◽  
Andrea C. Carcelen ◽  
Jacob M. Konikoff ◽  
Joe Williamson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Supply ◽  
Zika Virus ◽  
Blood Donation ◽  
Case Reports ◽  
Fold Increase ◽  
Pooled Analysis ◽  
Control Measures ◽  
History Of ◽  
And Control

Background Evidence suggests that Zika virus has driven a 10-fold increase in babies born with microcephaly in Brazil, prompting the WHO to declare a Public Health Emergency of International Concern. However, little is known about the natural history of infection. These data are critical for implementation of surveillance and control measures such as protecting the blood supply. Methods We conducted a systematic review and pooled analysis to estimate the distribution of times from Zika infection to symptom onset, seroconversion, and viral clearance, and analyzed their implications for surveillance and blood supply safety. Results Based on 25 case reports, we estimate the median incubation period of Zika virus infection is 5.9 days (95% CI: 4.4-7.6), and that 95% of cases will develop symptoms by 11.1 days post-infection (95% CI: 7.6-18.0). On average seroconversion occurs 9.0 days (95% CI, 7.0-11.6) after infection, and virus is detectable in blood for 9.9 days (95% CI: 6.8-21.4). In 5% of cases detectable virus persists for over 18.9 days (95% CI: 12.6-79.5). The baseline (no screening) risk of a blood donation being infected with Zika increases by approximately 1 in 10,000 for every 1 per 100,000 person-days increase in Zika incidence. Symptom based screening reduces this by 7% (RR 0.93, 93% CI 0.86-0.99), and antibody screening by 29% (RR 0.71, 95% CI: 0.28-0.88). Conclusions Symptom or antibody-based surveillance can do little to reduce the risk of Zika contaminated blood donations. High incidence areas may consider PCR testing to identify lots safe for use in pregnant women.

scholarly journals Emergence of Epidemic Zika Virus Transmission and Congenital Zika Syndrome: Are Recently Evolved Traits to Blame?

mBio ◽  
2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Scott C. Weaver
Keyword(s):  
Zika Virus ◽  
Virus Transmission ◽  
Severe Infection ◽  
Human Infection ◽  
Conclusive Evidence ◽  
Control Measures ◽  
Human Populations ◽  
Reverse Genetic ◽  
Congenital Zika Syndrome ◽  
And Control

ABSTRACT The mechanisms responsible for the dramatic emergence of Zika virus (ZIKV), accompanied by congenital Zika syndrome and Guillain-Barré syndrome (GBS), remain unclear. However, two hypotheses are prominent: (i) evolution for enhanced urban transmission via adaptation to mosquito vectors, or for enhanced human infection to increase amplification, or (ii) the stochastic introduction of ZIKV into large, naive human populations in regions with abundant Aedes aegypti populations, leading to enough rare, severe infection outcomes for their first recognition. Advances in animal models for human infection combined with improvements in serodiagnostics, better surveillance, and reverse genetic approaches should provide more conclusive evidence of whether mosquito transmission or human pathogenesis changed coincidentally with emergence in the South Pacific and the Americas. Ultimately, understanding the mechanisms of epidemic ZIKV emergence, and its associated syndromes, is critical to predict future risks as well as to target surveillance and control measures in key locations.

scholarly journals Zika Virus: A Basic Overview of an Emerging Arboviral Infection in the Western Hemisphere

2016 ◽  
Vol 10 (5) ◽  
pp. 707-712 ◽  
Author(s):  
Kelly G. Vest
Keyword(s):  
Public Health ◽  
Virus Infection ◽  
Zika Virus ◽  
Western Hemisphere ◽  
Control Measures ◽  
Historical Background ◽  
World Health ◽  
Zika Virus Infection ◽  
Health Organization ◽  
And Control

AbstractSince February 2015, Zika virus has spread throughout the Western Hemisphere, starting in Brazil. As of March 2016, autochthonous transmission has been reported in at least 31 countries or territories. For countries in the Americas, the spread of Zika virus, a previously unfamiliar disease, follows similar emerging infection introductions of West Nile virus and Chikungunya virus and their spread throughout the American continents and the Caribbean nations. The Pan American Health Organization and the World Health Organization have issued alerts and a Public Health Emergency of International Concern announcement related to the recent cluster of microcephaly cases and other neurological disorders in Brazil that are temporally associated with Zika virus, which highlights the possible adverse impact of viral infection. This article provides an overview of the Zika virus infection and presents the historical background of the virus, a description of the pathogen, the epidemiology and clinical spectrum of Zika virus infection, diagnosis and treatment approaches, and prevention and control measures. Understanding what is known about the virus and its clinical presentation will assist in prevention, detection, and response measures to reduce and control the spread of the virus throughout the Western Hemisphere. (Disaster Med Public Health Preparedness. 2016;page 1 of 6)

scholarly journals Travel-associated and autochthonous Zika virus infection in mainland France, 1 January to 15 July 2016

2016 ◽  
Vol 21 (32) ◽  
Author(s):  
A Septfons ◽  
I Leparc-Goffart ◽  
E Couturier ◽  
F Franke ◽  
J Deniau ◽  
...  
Keyword(s):  
Virus Infection ◽  
Aedes Albopictus ◽  
Zika Virus ◽  
Surveillance System ◽  
Control Measures ◽  
Risk Of Infection ◽  
Zikv Infection ◽  
Zika Virus Infection ◽  
And Control

During summer 2016, all the conditions for local mosquito-borne transmission of Zika virus (ZIKV) are met in mainland France: a competent vector, Aedes albopictus, a large number of travellers returning from ZIKV-affected areas, and an immunologically naive population. From 1 January to 15 July 2016, 625 persons with evidence of recent ZIKV infection were reported in mainland France. We describe the surveillance system in place and control measures implemented to reduce the risk of infection.

scholarly journals International travelers and genomics uncover a ‘hidden’ Zika outbreak

2018 ◽  
Author(s):  
Nathan D. Grubaugh ◽  
Sharada Saraf ◽  
Karthik Gangavarapu ◽  
Alexander Watts ◽  
Amanda L. Tan ◽  
...  
Keyword(s):  
Zika Virus ◽  
Public Health Surveillance ◽  
Mosquito Control ◽  
Herd Immunity ◽  
Virus Transmission ◽  
The United States ◽  
Control Measures ◽  
Local Case ◽  
Peak Transmission ◽  
And Control

AbstractThe ongoing Zika epidemic in the Americas has challenged public health surveillance, response, and control systems. Even as the epidemic appears to be near its end in the Americas, it is unclear whether substantial Zika virus transmission may still be ongoing. This issue is exacerbated by large discrepancies in local case reporting and significant delays in detecting outbreaks due to surveillance gaps. To uncover locations with lingering outbreaks in the Americas, we investigated travel-associated Zika cases diagnosed in the United States and Europe to identify signatures of transmission dynamics that were not captured by local reporting. We found that a large and unreported Zika outbreak occurred in Cuba during 2017, a year after peak transmission in neighboring countries, with cases still appearing in 2018. By sequencing Zika virus from infected travelers, we show that the 2017 outbreak in Cuba was sparked by long-lived lineages of Zika virus introduced from multiple places in the Americas a year prior. Our data suggest that while aggressive mosquito control in Cuba may initially have been effective at mitigating Zika virus transmission, in the absence of vaccines, herd immunity, or strong international coordination, such control measures may need to be maintained to be effective. Our study highlights how Zika virus may still be ‘silently’ spreading in the Americas and provides a framework for more accurately understanding outbreak dynamics.

Knowledge and Awareness of Dengue Fever

2018 ◽  
pp. 219-222
Author(s):  
Y. Arockia Suganthi ◽  
Chitra K. ◽  
J. Magelin Mary
Keyword(s):  
Dengue Fever ◽  
Prevention And Control ◽  
Control Measures ◽  
Infection Transmission ◽  
Standard Guideline ◽  
The World ◽  
Different Types ◽  
Prevention And Control Measures ◽  
Dengue Prevention ◽  
And Control

Dengue fever is a painful mosquito-borne infection caused by different types of virus in various localities of the world. There is no particular medicine or vaccine to treat person suffering from dengue fever. Dengue viruses are transmitted by the bite of female Aedes (Ae) mosquitoes. Dengue fever viruses are mainly transmitted by Aedes which can be active in tropical or subtropical climates. Aedes Aegypti is the key step to avoid infection transmission to save millions of people in all over the world. This paper provides a standard guideline in the planning of dengue prevention and control measures. At the same time gives the priorities including clinical management and hospitalized dengue patients have to address essentially.

The Mediterranean Action Plan: A Regional Approach to Pollution Control

1986 ◽  
Vol 18 (9) ◽  
pp. 197-205
Author(s):  
Lj Jeftié ◽  
L. J. Saliba
Keyword(s):  
Mediterranean Sea ◽  
Action Plan ◽  
Control Measures ◽  
Industrial Wastes ◽  
Pollution Monitoring ◽  
Environmental Preservation ◽  
Agricultural Pesticides ◽  
The Mediterranean ◽  
A Prospective Study ◽  
And Control

Increasing concern over the deterioration of the Mediterranean sea as a result of increasing pollution by untreated sewage and industrial wastes, agricultural pesticides and fertilizers and oil discharges, led to a series of meetings between 1970 and 1974, and finally to the UNEP-sponsored Mediterranean Action Plan, adopted by governments of the region in 1975 and ongoing since that time. The legal component of the Plan includes a framework Convention and four protocols; the environmental assessment component (the MED POL programme) consists of national pollution monitoring programmes, and research projects conducted by Mediterranean institutions; the environmental management component consists of the Blue Plan (a prospective study combining socio-economic development with environmental preservation) and the Priority Actions Programme (a series of sub-region sectoral projects in defined areas). The Plan has been financed by Mediterranean States since 1979, and is managed by UNEP with the cooperation of other competent UN Agencies. During the last ten years, activities undertaken have improved knowledge of the state of pollution of the Mediterranean sea, and facilitated joint regional action in the form of preventive and control measures.

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