Physical activity, sex steroid, and growth factor concentrations in pre- and post-menopausal women: a cross-sectional study within the EPIC cohort

2013 ◽  
Vol 25 (1) ◽  
pp. 111-124 ◽  
Author(s):  
S. Rinaldi ◽  
R. Kaaks ◽  
C. M. Friedenreich ◽  
T. J. Key ◽  
R. Travis ◽  
...  
2019 ◽  
Vol 32 (7) ◽  
pp. 1303-1308 ◽  
Author(s):  
Gloria Bonaccorsi ◽  
Francesco Pio Cafarelli ◽  
Carlo Cervellati ◽  
François De Guio ◽  
Pantaleo Greco ◽  
...  

2021 ◽  
Vol 19 (2) ◽  
pp. 157-164
Author(s):  
Muneera Almurdi ◽  
◽  
Syamala Buragadda ◽  

Objectives: Menopause is the termination of a woman’s menstrual cycle for a year. In this condition, women’s health status declines due to hormonal changes and aging. Physical Activity (PA) is among the best available alternatives for managing menopause-related symptoms without any adverse effects. This study aimed to assess the relationship between PA and symptoms, such as fatigue, depression, and insomnia in Saudi menopausal women. Methods: This cross-sectional study involved 60 menopausal women; they were divided into physically active and inactive groups. The group allocation was conducted based on their PA level determined by the International Physical Activity Questionnaire Short-Form (IPAQ-SF). Menopausal symptoms, such as fatigue, depression, and insomnia were assessed using the Fatigue Severity Scale (FSS), Beck Depression Inventory-II (BDI-II), and Insomnia Severity Index (ISI), respectively, in the study groups. The association between PA and fatigue, depression, and insomnia was assessed using the Pearson correlation coefficient. The significance level was set at P≤0.05. Results: Fatigue, depression, and insomnia were more prevalent in physically inactive post-menopause women than the active women. A significant difference was observed in the outcome variables between the study groups. Furthermore, a significant association was detected between PA and fatigue, depression, and insomnia in the study participants. Discussion: Half of the explored menopausal women were physically active. Physically active menopausal women presented less fatigue, depression, and insomnia, compared to their inactive counterparts. This study suggested that PA positively impacted menopausal symptoms (fatigue, insomnia, & depression). Besides, the collected results highlighted the importance of physical activity among menopausal women.


2020 ◽  
Author(s):  
Navaneethakrishnan Suganthan ◽  
Thirunavukarasu Kumanan ◽  
Vithegi Kesavan ◽  
Mahalingam Aravinthan ◽  
Nadarajah Rajeshkannan

Abstract Background Vitamin D deficiency is common among post-menopausal women and it is important to treat vitamin D deficiency to prevent falls and fractures in patients with osteoporosis. Few studies examined the prevalence of vitamin D deficiency in general population of Sri Lanka but no studies to date done among post-menopausal women with osteoporosis. This is the first study of such kind conducted to evaluate the serum vitamin D levels and factors related to Vitamin D deficiency among postmenopausal women.Methodology Hospital based Cross -sectional study was conducted at the Endocrine Unit, Teaching Hospital from January to December 2018.During the study period 105 postmenopausal women registered for DEXA scan with Endocrine Unit were recruited to the study. Data collection was done by investigators and blood sample was taken from each participant by registered nursing officers and sample was analysed by using immunohistochemistry assays. Serum Vitamin D levels were categorized and data analysis was done using SPSS 26.Results Mean age of 105 postmenopausal women was 67.7 with minimum 33 and maximum 84 years. Mean Vitamin D levels were 27.5(range11.7-52.5ng/ml). Vitamin D levels were adequate in only 36.2% (95%CI: 27.4-45.7) of women, 44% had insufficient levels and deficiency was present in 19% (95%CI: 12.4-27.4) of participants. Among the 105 women 20% were vegetarian and 53% of them consuming milk on average 3 days per week, 76.2% consuming fish on average 2 days per week, 64.8% consuming egg on average 1 day per week. Furthermore seventy five participants (71.4%) reported adequate level of sun exposure (>30minutes).Commonly reported vitamin deficiency symptoms includes paraesthesia (57.1%),bone pain (55.2%), easy fatigability (54.3%), malaise (51.4%), muscle cramps (43.8%) and proximal myopathy (40.0%).Among 71(66.7%) completed bone density assessment,38% (27.3-49.7) of them showed osteoporosis range. Vertebral Z score showed a significant correlation with vitamin D level(r-0.252, P-0.034).Conclusion Prevalence of vitamin D deficiency is relatively high among the post-menopausal women with a provisional diagnosis of osteoporosis. It is essential to correct vitamin D deficiency with supplementation when initiating treatment for osteoporosis. So vitamin D testing is desirable in decision making to treat or not to treat.


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