Chemopreventive effect of Padina boergesenii extracts on ferric nitrilotriacetate (Fe-NTA)-induced oxidative damage in Wistar rats

2010 ◽  
Vol 23 (2) ◽  
pp. 257-263 ◽  
Author(s):  
Rajamani Karthikeyan ◽  
T. Manivasagam ◽  
P. Anantharaman ◽  
T. Balasubramanian ◽  
S. T. Somasundaram
Keyword(s):  
Oxidative Damage ◽  
Wistar Rats ◽  
Ferric Nitrilotriacetate ◽  
Chemopreventive Effect

scholarly journals Modafinil Effects on Behavior and Oxidative Damage Parameters in Brain of Wistar Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Felipe Ornell ◽  
Samira S. Valvassori ◽  
Amanda V. Steckert ◽  
Pedro F. Deroza ◽  
Wilson R. Resende ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Open Field ◽  
Wistar Rats ◽  
Thiobarbituric Acid ◽  
Protein Carbonyl ◽  
Behavioral Changes ◽  
Protein Damage ◽  
Behavioral Parameters ◽  
Carbonyl Formation ◽  
The Brain

The effects of modafinil (MD) on behavioral and oxidative damage to protein and lipid in the brain of rats were evaluated. Wistar rats were given a single administration by gavage of water or MD (75, 150, or 300 mg/kg). Behavioral parameters were evaluated in open-field apparatus 1, 2, and 3 h after drug administration. Thiobarbituric acid reactive substances (TBARS) and protein carbonyl formation were measured in the brain. MD increased locomotor activity at the highest dose 1 and 3 h after administration. MD administration at the dose of 300 mg/kg increased visits to the center of open-field 1 h after administration; however, 3 h after administration, all administered doses of MD increased visits to the open-field center. MD 300 mg/kg increased lipid damage in the amygdala, hippocampus, and striatum. Besides, MD increased protein damage in the prefrontal cortex, amygdala, and hippocampus; however, this effect varies depending on the dose administered. In contrast, the administration of MD 75 and 300 mg/kg decreased the protein damage in the striatum. This study demonstrated that the MD administration induces behavioral changes, which was depending on the dose used. In addition, the effects of MD on oxidative damage parameters seemed to be in specific brain region and doses.

Zingerone prevents lead‐induced toxicity in liver and kidney tissues by regulating the oxidative damage in Wistar rats

2020 ◽  
Author(s):  
Insha Amin ◽  
Ishraq Hussain ◽  
Muneeb U. Rehman ◽  
Bilal Ahmad Mir ◽  
Showkat Ahmad Ganaie ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Wistar Rats ◽  
Liver And Kidney

DNA base modifications in renal chromatin of wistar rats treated with a renal carcinogen, ferric nitrilotriacetate

1994 ◽  
Vol 57 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Shinya Toyokuni ◽  
Toshiaki Mori ◽  
Miral Dizdaroglu
Keyword(s):  
Wistar Rats ◽  
Ferric Nitrilotriacetate ◽  
Dna Base ◽  
Base Modifications

Protective Mechanisms of Quercetin on Cisplatin Induced Oxidative Damage in Hepatic Tissue of Wistar Rats

2017 ◽  
Vol 88 (4) ◽  
pp. 1399-1407 ◽  
Author(s):  
Pawan K. Verma ◽  
Rajinder Raina ◽  
Shahid Prawez ◽  
Mudasir Sultana ◽  
Maninder Singh ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Wistar Rats ◽  
Hepatic Tissue ◽  
Protective Mechanisms

scholarly journals Chemopreventive Effect of Grape Juice on NF-Kappa B, Inos and Tnfα in Wistar Rats After Colon Carcinogenesis Induced by Azoximethane

2013 ◽  
Vol 24 ◽  
pp. iv117
Author(s):  
Vanessa Pazzine ◽  
Roseane Silva ◽  
Ana Paiotti ◽  
Daniel Ribeiro ◽  
Nora Forones
Keyword(s):  
Wistar Rats ◽  
Colon Carcinogenesis ◽  
Grape Juice ◽  
Nf Kappa B ◽  
Chemopreventive Effect
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