Surface modification of titanium thin film with chitosan via electrostatic self-assembly technique and its influence on osteoblast growth behavior

2007 ◽  
Vol 19 (2) ◽  
pp. 499-506 ◽  
Author(s):  
Kaiyong Cai ◽  
Yan Hu ◽  
Klaus D. Jandt ◽  
Yuanliang Wang
Keyword(s):  
Thin Film ◽  
Surface Modification ◽  
Self Assembly ◽  
Growth Behavior ◽  
Titanium Thin Film ◽  
Assembly Technique ◽  
Modification Of Titanium

scholarly journals Surface Modification of Titanium with Heparin-Chitosan Multilayers via Layer-by-Layer Self-Assembly Technique

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Yao Shu ◽  
Guomin Ou ◽  
Li Wang ◽  
Jingcai Zou ◽  
Quanli Li
Keyword(s):  
Surface Modification ◽  
Self Assembly ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Titanium Implants ◽  
Layer By Layer ◽  
Assembly Technique ◽  
Titanium Surfaces ◽  
Modification Of Titanium ◽  
Positively Charged

Extracellular matrix (ECM), like biomimetic surface modification of titanium implants, is a promising method for improving its biocompatibility. In this paper chitosan (Chi) and heparin (Hep) multilayer was coated on pure titanium using a layer-by-layer (LbL) self-assembly technique. The Hep-Chi multilayer growth was carried out by first depositing a single layer of positively charged poly-L-lysine (PLL) on the NaOH-treated titanium substrate (negatively charged surface), followed by alternate deposition of negatively charged Hep and positively charged Chi, and terminated by an outermost layer of Chi. The multilayer was characterized by DR-FTIR, SEM, and AFM, and osteoblasts were cocultured with the modified titanium and untreated titanium surfaces, respectively, to evaluate their cytocompatibilityin vitro. The results confirmed that Hep-Chi multilayer was fabricated gradually on the titanium surface. The Hep-Chi multilayer-coated titanium improved the adhesion, proliferation and differentiation of osteoblasts. Thus, the approach described here may provide a basis for the preparation of modified titanium surfaces for use in dental or orthopedic implants.

DYNAMIC BEHAVIOR OF METHYLENE BLUE ON E. coli K30 CAPSULAR POLYSACCHARIDE USING LAYER BY LAYER SELF-ASSEMBLY TECHNIQUE

2020 ◽  
pp. 2050027
Author(s):  
BANDANA DAS ◽  
ALPANA BAIDYA ◽  
SANTANU MAJUMDER ◽  
RANENDU KUMAR NATH
Keyword(s):  
Thin Film ◽  
Methylene Blue ◽  
Dynamic Behavior ◽  
Self Assembly ◽  
Capsular Polysaccharide ◽  
Layer By Layer ◽  
Cationic Dye ◽  
Bacterial Polysaccharide ◽  
E Coli ◽  
Assembly Technique

Layer-by-layer (LbL) self-assembly is one of the unique methods for fabrication of ultra-thin film. This technique has immense application aross many fields in today’s life. In this paper, we have presented the fabrication of the thin film comprising of antifungal and antibacterial cationic dye methylene blue with negatively charged E. coli K30 bacterial polysaccharide sharing with PAH. The multilayers were characterized by UV–Vis absorption spectra and AFM. Various photophysical behaviors were investigated. Such studies provide a new light in the research of layer by layer self-assembly technique.

scholarly journals Layer-by-Layer Deposition of Hyaluronan and Quercetin-Loaded Chitosan Nanoparticles onto Titanium for Improving Blood Compatibility

Coatings ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 256 ◽  
Author(s):  
Xingda Wu ◽  
Cuijuan Liu ◽  
Hongpeng Chen ◽  
Yanfang Zhang ◽  
Lin Li ◽  
...  
Keyword(s):  
Surface Modification ◽  
Self Assembly ◽  
Platelet Adhesion ◽  
Blood Compatibility ◽  
Chitosan Nanoparticles ◽  
Uv Spectra ◽  
Multilayer Coatings ◽  
Layer By Layer ◽  
Antithrombotic Effects ◽  
Assembly Technique

Surface modification is an effective way to improve the hemocompatibility of biomaterials. Quercetin has significant anticoagulation and antithrombotic effects, and thus it is a promising candidate agent for the surface modification of blood-contacting materials. In this study, quercetin was successfully encapsulated in tripolyphosphate–chitosan nanoparticles (TCs) based on the ionic gelation of chitosan with tripolyphosphate (TPP) anions. Then, hyaluronan acid (HA)/quercetin-loaded TPP–chitosan nanoparticle (QTCs) films, in addition to HA/TCs films, were prepared separately using an electrostatic layer-by-layer self-assembly technique. The encapsulation of quercetin in the chitosan nanoparticles was confirmed by UV spectra. The quercetin-loaded multilayer coatings were also successfully self-assembled, as confirmed by the UV spectra and contact angle measurements. Platelet adhesion experiments were carried out with platelet-enriched plasma so as to evaluate the blood compatibility of the different samples. There were many platelets on the surfaces of the glass and HA/TC-coated titanium, which were partially activated but not aggregated. Meanwhile, many more platelets were observed on the uncoated titanium surfaces, most of which developed pseudopodia. By contrast, the platelet adhesion and activation were reduced remarkably on the surface of the HA/QTC-coated titanium. These results showed that the multilayer coatings containing quercetin could act as potential biomaterials to improve the anticoagulation performance of blood-contacting materials.

scholarly journals Oxidation of boron-titanium thin film coating during cyclic tests on thermal shock

2020 ◽  
Vol 1005 ◽  
pp. 012006
Author(s):  
E E Suslov ◽  
A S Larionov ◽  
S B Kislitsin ◽  
I I Chernov ◽  
M S Staltsov ◽  
...  
Keyword(s):  
Thin Film ◽  
Thermal Shock ◽  
Film Coating ◽  
Cyclic Tests ◽  
Thin Film Coating ◽  
Titanium Thin Film
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