Phytosynthesis, Characterization and Fungicidal Potential of Emerging Gold Nanoparticles Using Pongamia pinnata Leave Extract: A Novel Approach in Nanoparticle Synthesis

2019 ◽  
Vol 31 (1) ◽  
pp. 125-131 ◽  
Author(s):  
Ashapurna Khatua ◽  
Eepsita Priyadarshini ◽  
Paulraj Rajamani ◽  
Amiyakumar Patel ◽  
Jitender Kumar ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Nanoparticle Synthesis ◽  
Pongamia Pinnata ◽  
Novel Approach

scholarly journals Continuous synthesis of gold nanoparticles in micro- and millifluidic systems

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
He Huang ◽  
Hendrik du Toit ◽  
Luca Panariello ◽  
Luca Mazzei ◽  
Asterios Gavriilidis
Keyword(s):  
Gold Nanoparticles ◽  
Nanoparticle Synthesis ◽  
Reactor Operation ◽  
Design Procedures ◽  
Time Control ◽  
Starting Point ◽  
Quantitative Understanding ◽  
Gold Nanomaterials ◽  
Gold Nanoparticle Synthesis ◽  
Flow Devices

Abstract Gold nanomaterials have diverse applications ranging from healthcare and nanomedicine to analytical sciences and catalysis. Microfluidic and millifluidic reactors offer multiple advantages for their synthesis and manufacturing, including controlled or fast mixing, accurate reaction time control and excellent heat transfer. These advantages are demonstrated by reviewing gold nanoparticle synthesis strategies in flow devices. However, there are still challenges to be resolved, such as reactor fouling, particularly if robust manufacturing processes are to be developed to achieve the desired targets in terms of nanoparticle size, size distribution, surface properties, process throughput and robustness. Solutions to these challenges are more effective through a coordinated approach from chemists, engineers and physicists, which has at its core a qualitative and quantitative understanding of the synthesis processes and reactor operation. This is important as nanoparticle synthesis is complex, encompassing multiple phenomena interacting with each other, often taking place at short timescales. The proposed methodology for the development of reactors and processes is generic and contains various interconnected considerations. It aims to be a starting point towards rigorous design procedures for the robust and reproducible continuous flow synthesis of gold nanoparticles. Graphical Abstract:

scholarly journals Enhanced Extracellular Synthesis of Gold Nanoparticles by Soluble Extracts from Escherichia coli Transformed with Rhizobium tropici Phytochelatin Synthase Gene

Metals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 472
Author(s):  
Qunying Yuan ◽  
Manjula Bomma ◽  
Zhigang Xiao
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Synthesis Method ◽  
Nanoparticle Synthesis ◽  
Morphological Properties ◽  
Phytochelatin Synthase ◽  
Rhizobium Tropici ◽  
Whole Cells ◽  
E Coli ◽  
Recombinant Cells

Phytochelatins, the enzymatic products of phytochelatin synthase, play a principal role in protecting the plants from heavy metal and metalloid toxicity due to their ability to scavenge metal ions. In the present study, we investigated the capacity of soluble intracellular extracts from E. coli cells expressing R. tropici phytochelatin synthase to synthesize gold nanoparticle. We discovered that the reaction mediated by soluble extracts from the recombinant E. coli cells had a higher yield of gold nanoparticles, compared to that from the control cells. The compositional and morphological properties of the gold nanoparticles synthesized by the intracellular extracts from recombinant cells and control cells were similar. In addition, this extracellular nanoparticle synthesis method produced purer gold nanoparticles, avoiding the isolation of nanoparticles from cellular debris when whole cells are used to synthesize nanoparticles. Our results suggested that phytochelatins can improve the efficiency of gold nanoparticle synthesis mediated by bacterial soluble intracellular extracts, and the potential of extracellular nanoparticle synthesis platform for the production of nanoparticles in large quantity and pure form is worth further investigation.

scholarly journals Cyanobacteria as Nanogold Factories II: Chemical Reactivity and anti-Myocardial Infraction Properties of Customized Gold Nanoparticles Biosynthesized by Cyanothece sp.

Marine Drugs ◽  
2019 ◽  
Vol 17 (7) ◽  
pp. 402 ◽  
Author(s):  
Nancy S. Younis ◽  
Esam M. Bakir ◽  
Maged E. Mohamed ◽  
Nermin A. El Semary
Keyword(s):  
Myocardial Infarction ◽  
Gold Nanoparticles ◽  
Chemical Reactivity ◽  
Characteristic Absorption Band ◽  
Novel Approach ◽  
Myocardial Infraction ◽  
Metal State ◽  
Chemical Conditions ◽  
Physiological And Biochemical ◽  
Successful Production

Cyanothece sp., a coccoid, unicellular, nitrogen-fixing and hydrogen-producing cyanobacterium, has been used in this study to biosynthesize customized gold nanoparticles under certain chemical conditions. The produced gold nanoparticles had a characteristic absorption band at 525–535 nm. Two types of gold nanoparticle, the purple and blue, were formed according to the chemical environment in which the cyanobacterium was grown. Dynamic light scattering was implemented to estimate the size of the purple and blue nanoparticles, which ranged from 80 ± 30 nm and 129 ± 40 nm in diameter, respectively. The highest scattering of laser light was recorded for the blue gold nanoparticles, which was possibly due to their larger size and higher concentration. The appearance of anodic and cathodic peaks in cyclic voltammetric scans of the blue gold nanoparticles reflected the oxidation into gold oxide, followed by the subsequent reduction into the nano metal state. The two produced forms of gold nanoparticles were used to treat isoproterenol-induced myocardial infarction in experimental rats. Both forms of nanoparticles ameliorated myocardial infarction injury, with a slight difference in their curative activity with the purple being more effective. Mechanisms that might explain the curative effect of these nanoparticles on the myocardial infarction were proposed. The morphological, physiological, and biochemical attributes of the Cyanothece sp. cyanobacterium were fundamental for the successful production of “tailored” nanoparticles, and complemented the chemical conditions for the differential biosynthesis process. The present research represents a novel approach to manipulate cyanobacterial cells towards the production of different-sized gold nanoparticles whose curative impacts vary accordingly. This is the first report on that type of manipulated gold nanoparticles biosynthesis which will hopefully open doors for further investigations and biotechnological applications.

A novel approach to imaging engorged ticks: Micro-CT scanning of Ixodes ricinus fed on blood enriched with gold nanoparticles

2021 ◽  
Vol 12 (1) ◽  
pp. 101559
Author(s):  
Jaroslav Ondruš ◽  
František Hubatka ◽  
Pavel Kulich ◽  
Nikola Odehnalová ◽  
Vratislav Harabiš ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ixodes Ricinus ◽  
Ct Scanning ◽  
Micro Ct ◽  
Novel Approach

scholarly journals Modulatory Effect of Citrate Reduced Gold and Biosynthesized Silver Nanoparticles on α-Amylase Activity

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Kantrao Saware ◽  
Ravindra Mahadappa Aurade ◽  
P. D. Kamala Jayanthi ◽  
Venkataraman Abbaraju
Keyword(s):  
Gold Nanoparticles ◽  
Silver Nanoparticles ◽  
Amylase Activity ◽  
Temperature Stability ◽  
Fold Increase ◽  
Free Enzyme ◽  
Catalytic Function ◽  
Ficus Benghalensis ◽  
Novel Approach ◽  
Immobilization Of Enzymes

Amylase is one of the important digestive enzymes involved in hydrolysis of starch. In this paper, we describe a novel approach to study the interaction of amylase enzyme with gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) and checked its catalytic function. AuNPs are synthesized using citrate reduction method and AgNPs were synthesized using biological route employing Ficus benghalensis and Ficus religiosa leaf extract as a reducing and stabilizing agent to reduce silver nitrate to silver atoms. A modulatory effect of nanoparticles on amylase activity was observed. Gold nanoparticles are excellent biocompatible surfaces for the immobilization of enzymes. Immobilized amylase showed 1- to 2-fold increase of activity compared to free enzyme. The biocatalytic activity of amylase in the bioconjugate was marginally enhanced relative to the free enzyme in solution. The bioconjugate material also showed significantly enhanced pH and temperature stability. The results indicate that the present study paves way for the modulator degradation of starch by the enzyme with AuNPs and biogenic AgNPs, which is a promising application in the medical and food industry.

A Novel Approach for the Synthesis of Gold Nanoparticles Using Trypsin

2014 ◽  
Vol 20 (5) ◽  
pp. 1061-1065 ◽  
Author(s):  
Salman Khan ◽  
Syed Mohd. Danish Rizvi ◽  
Mohd. Saeed ◽  
Ashwani Kr. Srivastava ◽  
Mohd. Sajid Khan
Keyword(s):  
Gold Nanoparticles ◽  
Novel Approach

Use of protease inhibitory gold nanoparticles as a compatibility enhancer for Bt and deltamethrin: A novel approach for pest control

2016 ◽  
Vol 8 ◽  
pp. 8-12 ◽  
Author(s):  
Chandrakant P. Narkhede ◽  
Rahul K. Suryawanshi ◽  
Chandrashekhar D. Patil ◽  
Hemant P. Borase ◽  
Satish V. Patil
Keyword(s):  
Gold Nanoparticles ◽  
Pest Control ◽  
Novel Approach

scholarly journals A microfluidic approach for synthesis and kinetic profiling of branched gold nanostructure

2021 ◽  
Author(s):  
Qi Cai ◽  
Valentina Castagnola ◽  
Luca Boselli ◽  
Alirio Moura ◽  
Hender Lopez ◽  
...  
Keyword(s):  
Nanoparticle Synthesis ◽  
Advanced Characterization ◽  
Particle Growth ◽  
Mechanistic Study ◽  
One Pot ◽  
Characterization Methods ◽  
Precise Control ◽  
Novel Approach ◽  
Gold Nanostructure

Automatized approaches for nanoparticle synthesis and characterization represent a great asset to their applicability in the biomedical field by improving reproducibility and standardization, which help to meet the selection criteria of regulatory authorities. The scaled-up production of nanoparticles with carefully defined characteristics, including intrinsic morphological features, minimal intra-batch, batch-to-batch, and operator variability, is an urgent requirement to elevate nanotechnology towards more trustable biological and technological applications. In this work, microfluidic approaches were employed to achieve fast mixing and good reproducibility in synthesizing a variety of gold nanostructures. The microfluidic setup allowed exploiting spatial resolution to investigate the growth evolution of the complex nanoarchitectures. By physically isolating intermediate reaction fractions, we performed an advanced characterization of the shape properties during their growth, not possible with routine characterization methods. Employing an in-house developed method to assign a specific identity to shapes, we followed the particle growth/deformation process and identified key reaction parameters for more precise control of the generated morphologies. Besides, this investigation led to the optimization of a one-pot multi-size and multi-shape synthesis of a variety of gold nanoparticles. In summary, we describe an optimized platform for highly controlled synthesis and a novel approach for the mechanistic study of shape-evolving nanomaterials.

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