The potential protective role of apigenin against oxidative damage induced by nickel oxide nanoparticles in liver and kidney of male Wistar rat, Rattus norvegicus

2021 ◽  
Author(s):  
Atef Abdel-Moneem Ali ◽  
Anwar Bakr Mansour ◽  
Shimaa Ahmed Attia
Keyword(s):  
Oxidative Damage ◽  
Nickel Oxide ◽  
Rattus Norvegicus ◽  
Wistar Rat ◽  
Protective Role ◽  
Oxide Nanoparticles ◽  
Nickel Oxide Nanoparticles ◽  
Liver And Kidney

TOXIC EFFECTS ASSESSMENT OF NICKEL OXIDE NANOPARTICLES BY INHALATION

2018 ◽  
pp. 24-29 ◽  
Author(s):  
B.A. Katsnelson ◽  
M.P. Sutunkova ◽  
L.I. Privalova ◽  
S.N. Solovjeva ◽  
V.B. Gurvich ◽  
...  
Keyword(s):  
Nickel Oxide ◽  
Redox Balance ◽  
Systemic Toxicity ◽  
Laboratory Animals ◽  
Oxide Nanoparticles ◽  
Nickel Oxide Nanoparticles ◽  
White Rats ◽  
Liver And Kidney ◽  
Stimulation Of Erythropoiesis ◽  
Nio Nps

The article presents in an experiment obtained principal results based on repeated low-level inhalation exposures of laboratory animals (white rats, outbred) to nickel oxide nanoparticles with a diameter of (23 ± 5) nm, 4 hours a day, 5 times a week for up to 10 months in a «nose only» installation. It was shown that non-specific body reactions to the action of NiO NPs include: diverse manifestations of systemic toxicity with a particularly pronounced influence on liver and kidney function, redox balance, damage to some areas of brain tissue, associated with proven movement of the nanoparticles themselves from the nasal mucosa along the olfactory tract; some cytological signs of probable development for allergic syndrome; paradoxically low severity of pulmonary pathology by pneumoconiotic type explained by a small chronic delay of nanoparticles in the lungs; the genotoxic effect of the organismal level, even at those low levels of chronic exposure, at which systemic toxicity is rather poorly. Along with that, NiO NPs also induce phase-stimulation of erythropoiesis, which is relatively specific for the toxic nickel effects.

scholarly journals The inhibitory role of synthesized Nickel oxide nanoparticles against Hep-G2, MCF-7, and HT-29 cell lines: the inhibitory role of NiO NPs against Hep-G2, MCF-7, and HT-29 cell lines

2021 ◽  
Vol 14 (3) ◽  
pp. 443-453
Author(s):  
Mohammad Amin Jadidi Kouhbanani ◽  
Yasin Sadeghipour ◽  
Mina Sarani ◽  
Erfan Sefidgar ◽  
Saba Ilkhani ◽  
...  
Keyword(s):  
Nickel Oxide ◽  
Cell Lines ◽  
Oxide Nanoparticles ◽  
Hep G2 ◽  
Nickel Oxide Nanoparticles ◽  
Inhibitory Role ◽  
Nio Nps ◽  
Ht 29 ◽  
Mcf 7

Increase of the Power of Solar Elements Based on Nanoparticles of Nickel Oxides Synthesized in Flame

2012 ◽  
Vol 486 ◽  
pp. 140-144 ◽  
Author(s):  
Zulkhair A. Mansurov ◽  
M. Aueylkhankyzy ◽  
Bakhytzhan T. Lesbaye ◽  
Dmitriy I. Chenchik ◽  
K.K. Dikhanbaev ◽  
...  
Keyword(s):  
Solar Cells ◽  
Nickel Oxide ◽  
Short Circuit ◽  
Short Circuit Current ◽  
Open Circuit ◽  
Oxide Nanoparticles ◽  
Nickel Oxide Nanoparticles ◽  
Photoelectrical Properties ◽  
The Given

The present work is devoted to studying photoelectrical properties of the solar cells covered with nickel oxide nanoparticles synthesized in counter flow propane flame. In the given case, the nanoparticles of oxides play the role of quantum points on the surface of the solar cells and promotes effective absorption of light energy. The applying of silicon solar cells of nickel oxide nanoparticles to the surface caused the increase of output open circuit voltage of 4-7 %, the increase of short - circuit current of 20 - 28 %, that in total caused the increase of efficiency of the solar cells by 2-3%.

scholarly journals Dietary quercetin abrogates hepatorenal oxidative damage associated with dichloromethane exposure in rats

2019 ◽  
Author(s):  
Solomon E Owumi ◽  
Olabisi F Danso ◽  
Magdalene E Effiong
Keyword(s):  
Oxidative Damage ◽  
Protective Role ◽  
Gamma Glutamyl Transferase ◽  
Glutathione S Transferase ◽  
Histological Changes ◽  
Chlorinated Solvent ◽  
Household Products ◽  
Liver And Kidney ◽  
Glutamyl Transferase

Exposure to dichloromethane (DCM), a commonly used chlorinated solvent in industrial settings and for the production of many household products, reportedly elicits detrimental effects in animals and humans. The present study investigated the protective role of dietary quercetin on DCM-induced hepatorenal damage in rats. Experimental rats were orally administered with DCM (150 mg/kg) and 30 min later with quercetin at 10, 20 and 40 mg/kg or none for 7 consecutive days. The results indicated that DCM-mediated significant (p<0.05) increases in serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase and alkaline phosphatase activities as well as urea and creatinine levels were dose-dependently normalized to the control values in rats co-treated with quercetin. Further, quercetin co-treatment ameliorated DCM-mediated decrease in the hepatic and renal activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione S-transferase as well as glutathione level in the treated rats. Moreover, quercetin co-treatment markedly reduced lipid peroxidation level and protected against histological changes in liver and kidney of the treated rats. Taken together, quercetin abrogated hepatorenal oxidative damage in DCM-treated rats via improvement of antioxidant status and suppression of oxidative damage.

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