Association between satellite-based estimates of long-term PM2.5 exposure and cardiovascular disease: evidence from the Indonesian Family Life Survey

Author(s):  
Sepridawati Siregar ◽  
Nora Idiawati ◽  
Wen-Chi Pan ◽  
Kuo-Pin Yu
2019 ◽  
Vol 49 (1) ◽  
pp. 25-35 ◽  
Author(s):  
Richard B Hayes ◽  
Chris Lim ◽  
Yilong Zhang ◽  
Kevin Cromar ◽  
Yongzhao Shao ◽  
...  

Abstract Background Ambient air pollution is a modifiable risk factor for cardiovascular disease, yet uncertainty remains about the size of risks at lower levels of fine particulate matter (PM2.5) exposure which now occur in the USA and elsewhere. Methods We investigated the relationship of ambient PM2.5 exposure with cause-specific cardiovascular disease mortality in 565 477 men and women, aged 50 to 71 years, from the National Institutes of Health-AARP Diet and Health Study. During 7.5 x 106 person-years of follow up, 41 286 cardiovascular disease deaths, including 23 328 ischaemic heart disease (IHD) and 5894 stroke deaths, were ascertained using the National Death Index. PM2.5 was estimated using a hybrid land use regression (LUR) geostatistical model. Multivariate Cox regression models were used to estimate relative risks (RRs) and 95% confidence intervals (CI). Results Each increase of 10  μg/m3 PM2.5 (overall range, 2.9–28.0  μg/m3) was associated, in fully adjusted models, with a 16% increase in mortality from ischaemic heart disease [hazard ratio (HR) 1.16; 95% CI 1.09-1.22] and a 14% increase in mortality from stroke (HR 1.14; CI 1.02-1.27). Compared with PM2.5 exposure <8  μg/m3 (referent), risks for CVD were increased in relation to PM2.5 exposures in the range of 8–12  μg/m3 (CVD: HR 1.04; 95% CI 1.00-1.08), in the range 12–20  μg/m3 (CVD: HR 1.08; 95% CI 1.03-1.13) and in the range 20+ μg/m3 (CVD: HR 1.19; 95% CI 1.10-1.28). Results were robust to alternative approaches to PM2.5 exposure assessment and statistical analysis. Conclusions Long-term exposure to fine particulate air pollution is associated with ischaemic heart disease and stroke mortality, with excess risks occurring in the range of and below the present US long-term standard for ambient exposure to PM2.5 (12  µg/m3), indicating the need for continued improvements in air pollution abatement for CVD prevention.


2020 ◽  
Vol 14 (1) ◽  
pp. 103-110
Author(s):  
Tantry Maulina ◽  
Cut Novianti Rachmi

Background: Overweight/obesity remains one of the most important health issues. Not only due to the current health consequences but also because of its long-term effect. One of the most common health problems experienced by an individual with overweight/obesity is dental problem, which can be reflected from dental pain being complained. Objective: The objective of the current study was to evaluate the association of overweight/obesity to be the predictor of the occurrence of dental pain. Methods: Data from the Indonesian Family Life Survey (IFLS) from five consecutive survey waves (1993, 1997, 2000, 2007 and 2014) that involved more than 30.000 participants and their offsprings that were grouped into three different age categories (0-4.9 years old; 5-19.9 years old; and 20-49.9 years old) were gathered and analyzed for Odds Ratio (OR) and Confidence Interval (CI). Trends of childhood overweight/obesity, the occurrence of dental pain, as well as the likelihood of individuals with childhood overweight/obesity to develop dental pain were analyzed by using STATA Data Analysis and Statistical Software version 13. Results: The results of the current study revealed that all age groups exhibited an increase in numbers when it comes to the prevalence of overweight/obesity from the first wave (in 1993) up to the latest wave (in 2014). It was also revealed that those who were in the 0-4.9 years old age group, were those who were more likely to develop dental pain (OR:1.12; 95% CI: 0.84-1.5; p:0.44). Conclusion: Despite the wave to wave variation, overweight/obesity has the potential to be associated with future dental problems, with dental pain in particular.


2020 ◽  
Vol 4 (1) ◽  
pp. 73-96
Author(s):  
Gilbert ◽  
Pricilia Meidy Winengko ◽  
Adho Adinegoro

The COVID-19 pandemic has affected most parts of society, one of which is the MSME household. Although various assistance has been addressed to this sector in the short term, a long-term strategy through digital financial inclusion is needed to reduce the vulnerability of MSME households to falling into poverty in the long term. Using data from the Indonesian Family Life Survey 2014, this study investigates the impact of digital finan-cial inclusion on the vulnerability of MSME households in Indonesia and in East Java. The OLS and 2SLS analysis shows that digital financial inclusion helped reduce the poverty vulnerability of MSME households significantly. Further logistic regression analysis also shows that the reduction of poverty vulnerability occurred both in the risk-induced and structural vulnerabilities. Based on the findings, this study recommends policy stakeholders to formulate a digital financial inclusion strategy as one of the alternative policies for poverty alleviation in Indonesia.


2019 ◽  
Vol 122 ◽  
pp. 193-200 ◽  
Author(s):  
Laura A. McGuinn ◽  
Alexandra Schneider ◽  
Robert W. McGarrah ◽  
Cavin Ward-Caviness ◽  
Lucas M. Neas ◽  
...  

2021 ◽  
Vol 10 (8) ◽  
pp. 1584
Author(s):  
Małgorzata Chlabicz ◽  
Jacek Jamiołkowski ◽  
Wojciech Łaguna ◽  
Paweł Sowa ◽  
Marlena Paniczko ◽  
...  

Background: Cardiovascular disease (CVD) is a major, worldwide problem that remains the dominant cause of premature mortality in the world, and increasing rates of dysglycaemia are a major contributor to its development. The aim of this study was to investigate the cardiometabolic profile among patients in particular cardiovascular risk classes, and to estimate their long term CV risk. Methods: A total of 931 individuals aged 20–79 were included. The study population was divided into CV risk classes according to the latest European Society of Cardiology recommendations. Results: Most of the analyzed anthropometric, body composition and laboratory parameters did not differ between the moderate and high CV risk participants. Interestingly, estimating the lifetime risk of myocardial infarction, stroke or CV death, using the LIFEtime-perspective model for individualizing CardioVascular Disease prevention strategies in apparently healthy people, yielded similar results in moderate and high CV risk classes. Conclusion: The participants who belonged to moderate and high CV risk classes had very similar unfavorable cardiometabolic profiles, which may result in similar lifetime CV risk. This may imply the need for more aggressive pharmacological and non-pharmacological management of CV risk factors in the moderate CV risk population, who are often unaware of their situation. New prospective population studies are necessary to establish the true cardiovascular risk profiles in a changing society.


2021 ◽  
pp. bmjnph-2020-000198
Author(s):  
Mengna Huang ◽  
Kenneth Lo ◽  
Jie Li ◽  
Matthew Allison ◽  
Wen-Chih Wu ◽  
...  

ObjectiveTo evaluate the association between pasta meal intake and long-term risk of developing diabetes or atherosclerotic cardiovascular disease (ASCVD, including coronary heart disease (CHD) and stroke) in postmenopausal women.DesignProspective cohort study.SettingWomen’s Health Initiative (WHI) in the USA.Participants84 555 postmenopausal women aged 50–79 in 1994, who were free of diabetes, ASCVD and cancer at baseline who were not in the dietary modification trial of the WHI, completed a validated food frequency questionnaire, and were evaluated for incident diabetes and ASCVD outcomes during the follow-up until 2010.Main outcome measureDiabetes and ASCVD.ResultsCox proportional hazards models were used to estimate the association (HR) between quartiles of pasta meal consumption (residuals after adjusting for total energy) and the risk of incidence diabetes, CHD, stroke or ASCVD, accounting for potential confounding factors, with testing for linear trend. We then statistically evaluated the effect of substituting white bread or fried potato for pasta meal on disease risk. When comparing the highest to the lowest quartiles of residual pasta meal intake, we observed significantly reduced risk of ASCVD (HR=0.89, 95% CI 0.83 to 0.96, p trend=0.002), stroke (HR=0.84, 95% CI 0.75 to 0.93, p trend=0.001), CHD (HR=0.91, 95% CI 0.83 to 1.00, p trend=0.058) and no significant alteration in diabetes risk (HR=1.02, 95% CI 0.96 to 1.07, p trend=0.328). Replacing white bread or fried potato with pasta meal was statistically associated with decreased risk of stroke and ASCVD.ConclusionsPasta meal intake did not have adverse effects on long-term diabetes risk and may be associated with significant reduced risk of stroke and ASCVD. The potential benefit of substituting pasta meal for other commonly consumed starchy foods on cardiometabolic outcomes warrants further investigation in additional high-quality and large prospective studies of diverse populations.


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