scholarly journals Correction to: Generative image transformer (GIT): unsupervised continuous image generative and transformable model for [123I]FP-CIT SPECT images

Author(s):  
Shogo Watanabe ◽  
Tomohiro Ueno ◽  
Yuichi Kimura ◽  
Masahiro Mishina ◽  
Naozo Sugimoto
Author(s):  
Shogo Watanabe ◽  
Tomohiro Ueno ◽  
Yuichi Kimura ◽  
Masahiro Mishina ◽  
Naozo Sugimoto

2008 ◽  
Vol 47 (01) ◽  
pp. 01-07 ◽  
Author(s):  
N. Thoma ◽  
M. Dietlein ◽  
D. Moka ◽  
W. Eschner ◽  
M. Faust ◽  
...  

SummaryAim of the study was to analyse the influence of a concomitant vitamin D deficiency on the results of 99mTc-MIBI studies in patients (pts) with primary hyperparathyroidism (pHPT). Patients, methods: Between January 1998 and May 2004, 71 pts with pHPT had undergone operation after a 99mTc-MIBI study of whom 54 pts (76%) had normal values of 25-OH-vitamin D3 and 17 pts (24%) had vitamin D deficiency. Results of a dual-phase 99mTc-MIBI protocol with SPECT were compared with histopathology. Results: In 54 pts with normal vitamin D values late SPECT images identified more lesions (n = 51, sensitivity 91%) than early planar (n = 45, sensitivity 82%) or late planar images (n = 50, sensitivity 88%). In 17 pts with vitamin D deficiency late SPECT images identified more lesions (n = 13, sensitivity 72%) than early planar (n = 10, sensitivity 56%) or late planar images (n = 10, sensitivity 56%) too. In pts with vitamin D deficiency the sensitivity of a 99mTc-MIBI SPECT study was lower than in those with normal vitamin D status (72% vs. 91%) and dependent on the value for PTH. However, the results did not reach statistical significance: early planar: p = 0.1625; late planar: p = 0.0039; 99mTc-MIBI SPECT: p = 0.1180. Conclusion: The likelihood of a pathological 99mTc-MIBI study being obtained in pts with pHPT is dependent on the parathyroid hormone level. However, a negative influence of a low vitamin D level on the scintigraphic detection rate of a parathyroid adenoma could not be proven which may be due to the low number of pts with vitamin D deficiency.


Author(s):  
Yuejun Liu ◽  
Yifei Xu ◽  
Xiangzheng Meng ◽  
Xuguang Wang ◽  
Tianxu Bai

Background: Medical imaging plays an important role in the diagnosis of thyroid diseases. In the field of machine learning, multiple dimensional deep learning algorithms are widely used in image classification and recognition, and have achieved great success. Objective: The method based on multiple dimensional deep learning is employed for the auxiliary diagnosis of thyroid diseases based on SPECT images. The performances of different deep learning models are evaluated and compared. Methods: Thyroid SPECT images are collected with three types, they are hyperthyroidism, normal and hypothyroidism. In the pre-processing, the region of interest of thyroid is segmented and the amount of data sample is expanded. Four CNN models, including CNN, Inception, VGG16 and RNN, are used to evaluate deep learning methods. Results: Deep learning based methods have good classification performance, the accuracy is 92.9%-96.2%, AUC is 97.8%-99.6%. VGG16 model has the best performance, the accuracy is 96.2% and AUC is 99.6%. Especially, the VGG16 model with a changing learning rate works best. Conclusion: The standard CNN, Inception, VGG16, and RNN four deep learning models are efficient for the classification of thyroid diseases with SPECT images. The accuracy of the assisted diagnostic method based on deep learning is higher than that of other methods reported in the literature.


Author(s):  
Anna Teresińska ◽  
Olgierd Woźniak ◽  
Aleksander Maciąg ◽  
Jacek Wnuk ◽  
Jarosław Jezierski ◽  
...  

Abstract Objective Impaired cardiac adrenergic activity has been demonstrated in heart failure (HF) and in diabetes mellitus (DM). [123I]I-metaiodobenzylguanidine (MIBG) enables assessment of the cardiac adrenergic nervous system. Tomographic imaging of the heart is expected to be superior to planar imaging. This study aimed to determine the quality and utility of MIBG SPECT in the assessment of cardiac innervation in postinfarction HF patients without DM, qualified for implantable cardioverter defibrillator (ICD) in primary prevention of sudden cardiac death. Methods Consecutive patients receiving an ICD on the basis of contemporary guidelines were prospectively included. Planar MIBG studies were followed by SPECT. The essential analysis was based on visual assessment of the quality of SPECT images (“high”, “low” or “unacceptable”). The variables used in the further analysis were late summed defect score for SPECT images and heart-to-mediastinum rate for planar images. MIBG images were assessed independently by two experienced readers. Results Fifty postinfarction nondiabetic HF subjects were enrolled. In 13 patients (26%), the assessment of SPECT studies was impossible. In addition, in 13 of 37 patients who underwent semiquantitative SPECT evaluation, the assessment was equivocal. Altogether, in 26/50 patients (52%, 95% confidence interval 38–65%), the quality of SPECT images was unacceptable or low and was limited by low MIBG cardiac uptake and by comparatively high, interfering MIBG uptake in the neighboring structures (primarily, in the lungs). Conclusions The utility of MIBG SPECT imaging, at least with conventional imaging protocols, in the qualification of postinfarction HF patients for ICD, is limited. In approximately half of the postinfarction HF patients, SPECT assessment of cardiac innervation can be impossible or equivocal, even without additional damage from diabetic cardiac neuropathy. The criteria predisposing the patient to good-quality MIBG SPECT are: high values of LVEF from the range characterizing the patients qualified to ICD (i.e., close to 35%) and left lung uptake intensity in planar images comparable to or lower than heart uptake.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Takayuki Shibutani ◽  
Masahisa Onoguchi ◽  
Yuka Naoi ◽  
Hiroto Yoneyama ◽  
Takahiro Konishi ◽  
...  

AbstractThe aim of this study was to demonstrate the usefulness of SwiftScan with a low-energy high-resolution and sensitivity (LEHRS) collimator for bone scintigraphy using a novel bone phantom simulating the human body. SwiftScan planar image of lateral view was acquired in clinical condition; thereafter, each planar image of different blend ratio (0–80%) of Crality 2D processing were created. SwiftScan planar images with reduced acquisition time by 25–75% were created by Poisson’s resampling processing. SwiftScan single photon emission computed tomography (SPECT) was acquired with step-and-shoot and continuous mode, and SPECT images were reconstructed using a three-dimensional ordered subset expectation maximization incorporating attenuation, scatter and spatial resolution corrections. SwiftScan planar image showed a high contrast to noise ratio (CNR) and low percent of the coefficient of variance (%CV) compared with conventional planar image. The CNR of the tumor parts in SwiftScan SPECT was higher than that of the conventional SPECT image of step and shoot acquisition, while the %CV showed the lowest value in all systems. In conclusion, SwiftScan planar and SPECT images were able to reduce the image noise compared with planar and SPECT image with a low-energy high-resolution collimator, so that SwiftScan planar and SPECT images could be obtained a high CNR. Furthermore, the SwiftScan planar image was able to reduce the acquisition time by 25% when the blend ratio of Clarity 2D processing set to more than 40%.


Author(s):  
Duo Zhang ◽  
P. Hendrik Pretorius ◽  
Kaixian Lin ◽  
Weibing Miao ◽  
Jingsong Li ◽  
...  

Biomedicines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 12
Author(s):  
Chung-Yao Chien ◽  
Szu-Wei Hsu ◽  
Tsung-Lin Lee ◽  
Pi-Shan Sung ◽  
Chou-Ching Lin

Background: The challenge of differentiating, at an early stage, Parkinson’s disease from parkinsonism caused by other disorders remains unsolved. We proposed using an artificial neural network (ANN) to process images of dopamine transporter single-photon emission computed tomography (DAT-SPECT). Methods: Abnormal DAT-SPECT images of subjects with Parkinson’s disease and parkinsonism caused by other disorders were divided into training and test sets. Striatal regions of the images were segmented by using an active contour model and were used as the data to perform transfer learning on a pre-trained ANN to discriminate Parkinson’s disease from parkinsonism caused by other disorders. A support vector machine trained using parameters of semi-quantitative measurements including specific binding ratio and asymmetry index was used for comparison. Results: The predictive accuracy of the ANN classifier (86%) was higher than that of the support vector machine classifier (68%). The sensitivity and specificity of the ANN classifier in predicting Parkinson’s disease were 81.8% and 88.6%, respectively. Conclusions: The ANN classifier outperformed classical biomarkers in differentiating Parkinson’s disease from parkinsonism caused by other disorders. This classifier can be readily included into standalone computer software for clinical application.


2019 ◽  
Vol 57 ◽  
pp. 153-159 ◽  
Author(s):  
Domenico Finocchiaro ◽  
Salvatore Berenato ◽  
Elisa Grassi ◽  
Valentina Bertolini ◽  
Gastone Castellani ◽  
...  

2006 ◽  
Vol 30 (1) ◽  
pp. 43-51
Author(s):  
Byeong-il Lee ◽  
Byong-Hwan Son ◽  
Hyun-Ju Choi ◽  
Hae-Gil Hwang ◽  
Hye-Young Kim ◽  
...  

2015 ◽  
Vol 43 (4) ◽  
pp. 282-288 ◽  
Author(s):  
L. A. Guner ◽  
B. Caliskan ◽  
I. Isik ◽  
T. Aksoy ◽  
E. Vardareli ◽  
...  

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