Ionic complex of risedronate with positively charged deoxycholic acid derivative: evaluation of physicochemical properties and enhancement of intestinal absorption in rats

Photocatalytic is one of the inexpensive and non-toxic techniques for degradation of organic pollutants into harmless substances such as water and carbon dioxide. In this study, simple electrolysis method was used in preparation of Ag/TiO2 and α-Fe2O3/HY catalysts. The physicochemical properties of the catalysts were studied using XRD, FTIR, FESEM-EDX and surface area analysis. The pH of solution plays an important role in the photocatalytic degradation of organic pollutants which influences the surface-charge properties of the catalysts. Ag/TiO2 and α-Fe2O3/HY were used as catalyst on degradation of 2-chlorophenol (2-CP) and methyl orange (MO), respectively. The effect of pH on degradation of 2-CP and MO were investigated over a pH range from 2 to 9. Higher degradation of 2-CP and MO were obtained at pH 5 (74%) and pH 2 (80%), respectively. This finding might be explained by the amphoteric performance of the catalyst using point zero charge (pHZPC). The pHZPC for Ag/TiO2 and α-Fe2O3/HY was found to be at pH 6.3 and pH 7.2, respectively. Hence, the activities of the catalysts may have been affected by the existence of a strong electrostatic field between the positively charged catalysts surface and negatively charged 2-CP and MO caused a pH value lower than their pHZPC give greater degradation.

Download Full-text

Effect of hydrocolloids on physicochemical properties, stability, and digestibility of Pickering emulsions stabilized by nanofibrillated cellulose

Food & Function ◽

10.1039/d1fo02933a ◽

2022 ◽

Author(s):

Nuttinee Tangsrianugul ◽

Thunnalin Winuprasith ◽

Manop Suphantharika ◽

Jirarut Wongkongkatep

Keyword(s):

Physicochemical Properties ◽

Xanthan Gum ◽

Guar Gum ◽

Nanofibrillated Cellulose ◽

Pickering Emulsions ◽

Positively Charged

In this study, effect of hydrocolloids with different electrostatic characteristics, i.e. negatively charged xanthan gum (XG), positively charged chitosan (CH), and non-ionic guar gum (GG) on physicochemical properties, stability, and...

Download Full-text

Correlation between physicochemical properties of superparamagnetic iron oxide nanoparticles and their reactivity with hydrogen peroxide

Canadian Journal of Chemistry ◽

10.1139/cjc-2020-0087 ◽

2020 ◽

Vol 98 (10) ◽

pp. 601-608

Author(s):

Taraneh Javanbakht ◽

Sophie Laurent ◽

Dimitri Stanicki ◽

Mathieu Frenette

Keyword(s):

Hydrogen Peroxide ◽

Iron Oxide ◽

Physicochemical Properties ◽

Iron Oxide Nanoparticles ◽

Superparamagnetic Iron Oxide ◽

Surface Modifications ◽

Oxide Nanoparticles ◽

Amine Groups ◽

The Comparative Study ◽

Positively Charged

The present study focuses on the effects of the physicochemical properties of superparamagnetic PEG-modified, positively charged, and negatively charged iron oxide nanoparticles (SPIONs) on their reactivity with hydrogen peroxide. Our hypothesis was that the reactivity of SPIONs in this reaction would depend on their surface properties. The comparative study of the nanoparticles with DLS and TEM revealed the average sizes of PEG-modified, positively charged, and negatively charged SPIONs. We observed that the reactivity of negatively charged SPIONs with hydrogen peroxide was less than that of positively charged SPIONs and that of these second nanoparticles was less than that of PEG-modified SPIONs. This difference in the reactivity of these SPIONs with hydrogen peroxide was attributed to the presence of carboxyl or amine groups on their surface. However, the values of the rate constants of the reactions of PEG-modified, positively charged, and negatively charged SPIONs with hydrogen peroxide showed that the reaction of negatively charged SPIONs with hydrogen peroxide was more rapid than that of PEG-modified SPIONs and the reaction of these second SPIONs with hydrogen peroxide was more rapid than that of positively charged SPIONs. The surface study of the SPIONs using XPS showed that the high-resolution spectra of these nanoparticles changed after reaction with hydrogen peroxide, which indicates their surface modifications. These investigations can help develop more appropriate nanoparticles with controlled physicochemical properties.

Download Full-text

Ionic complex of fullerene C602− dianions with (MDABCO+)2·MnIITPP coordination assemblies: synthesis, crystal structure and magnetic properties

Journal of Porphyrins and Phthalocyanines ◽

10.1142/s1088424608000510 ◽

2008 ◽

Vol 12 (11) ◽

pp. 1146-1153 ◽

Cited By ~ 10

Author(s):

Dmitri V. Konarev ◽

Salavat S. Khasanov ◽

Gunzi Saito ◽

Rimma N. Lyubovskaya

Keyword(s):

High Spin ◽

Spin State ◽

Magnetic Measurements ◽

High Spin State ◽

Radial Expansion ◽

Ionic Complex ◽

Porphyrin Core ◽

First Time ◽

Center Distance ◽

Positively Charged

The crystals of the ionic complex containing fullerene C 602− dianions and positively charged ( MDABCO +)2· Mn II TPP assemblies: {( MDABCO +)2·MnII TPP }·( C 602−)·( C 6 H 4 Cl 2)4·( CH 3 CN )2 (1) were obtained for the first time ( MDABCO +: the cation of N-methyldiazabicyclooctane; TPP: tetraphenylporphyrin). The C 602− dianions are isolated in the complex with the shortest center-to-center distance of 13.228 Å. The Mn II atoms are six-coordinated in the ( MDABCO +)2· Mn II TPP units. The length of the Mn-N(TPP) equatorial bonds of 2.093-2.098(1) Å corresponds to the high-spin state of the Mn II atoms (S = 5/2) which was confirmed by the magnetic measurements (µ eff = 5.61 µ B at 300 K). The Mn II atoms are located exactly in the porphyrin plane and this results in the radial expansion of the porphyrin core. The long (2.537(1)−2.545(1) Å) Mn - N ( MDABCO +) axial bonds indicate essential destabilization of the six-coordinated ( MDABCO +)2· Mn II TPP units due to the population of the d ( z 2) orbital in high-spin state. The contribution from the C 602− dianions was not found in magnetic measurements on the basis of the contribution from high-spin Mn II TPP and most probably they are diamagnetic in the 2-300 K range.

Download Full-text

Influence on the physicochemical properties of fish collagen gels using self-assembly and simultaneous cross-linking with theN-hydroxysuccinimide adipic acid derivative

Connective Tissue Research ◽

10.3109/03008207.2015.1020941 ◽

2015 ◽

Vol 56 (3) ◽

pp. 244-252 ◽

Cited By ~ 11

Author(s):

Lirui Shen ◽

Zhenhua Tian ◽

Wentao Liu ◽

Guoying Li

Keyword(s):

Physicochemical Properties ◽

Acid Derivative ◽

Adipic Acid ◽

Self Assembly ◽

Cross Linking ◽

Collagen Gels ◽

Fish Collagen

Download Full-text

Physicochemical Properties and Intestinal Absorption of a Ground Mixture of Chloramphenicol Palmitate with Microcrystalline Cellulose

YAKUGAKU ZASSHI ◽

10.1248/yakushi1947.97.4_367 ◽

1977 ◽

Vol 97 (4) ◽

pp. 367-372 ◽

Cited By ~ 4

Author(s):

KEIJI YAMAMOTO ◽

SHUJI MATSUDA ◽

MASAHIRO NAKANO ◽

TAKAICHI ARITA ◽

YOSHINOBU NAKAI

Keyword(s):

Physicochemical Properties ◽

Intestinal Absorption ◽

Microcrystalline Cellulose ◽

Ground Mixture

Download Full-text

A General Approach for the Prediction of the Intestinal Absorption of Drugs: Regression Analysis Using the Physicochemical Properties and Drug–Membrane Electrostatic Interaction

Journal of Pharmaceutical Sciences ◽

10.1021/js970451q ◽

1998 ◽

Vol 87 (8) ◽

pp. 960-966 ◽

Cited By ~ 45

Author(s):

Mitsuru Sugawara ◽

You Takekuma ◽

HarumiYamada ◽

MichiyaKobayashi ◽

Ken Isek ◽

...

Keyword(s):

Regression Analysis ◽

Physicochemical Properties ◽

Intestinal Absorption ◽

Electrostatic Interaction

Download Full-text

The crystal structure of 1-phenyl-3,5-dimethyl pyrazolium nitrate

Canadian Journal of Chemistry ◽

10.1139/v82-018 ◽

1982 ◽

Vol 60 (2) ◽

pp. 97-99 ◽

Cited By ~ 6

Author(s):

J. Zukerman-Schpector ◽

E. E. Castellano ◽

A. C. Massabni ◽

A. Derbli Pinto

Keyword(s):

Crystal Structure ◽

Title Compound ◽

Narrow Range ◽

Ionic Complex ◽

Full Matrix ◽

X Ray ◽

R Factor ◽

Cell Dimensions ◽

Positively Charged ◽

Rotational Freedom

The crystal structure of the title compound has been determined from diffractometric X-ray data and refined by full-matrix least-squares to a final R factor of 0.055 from 1099 independent reflections above background.The space group and cell dimensions are: P21/n, a = 7.916(2), b = 10.934(3), c = 13.638(1) Å, β = 97.37(1)°, with Z = 4.The 1-phenyl-3,5-dimethylpyrazole group was found to be positively charged, forming a strong ionic complex with the nitrate ion.The dihedral angle between the phenyl and pyrazole rings, corresponding to the minimum intramolecular van der Waals energy, was calculated and compared with those reported in different complexes of known structure, showing that there is a narrow range of rotational freedom about the N(1)—C(6) bond.

Download Full-text