A simple and reliable analytical method based on HPLC–UV to determine oleanonic acid content in Chios gum mastic for quality control

2016 ◽  
Vol 40 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Yan Jin ◽  
Jing Zhao ◽  
Kyung Min Jeong ◽  
Da Eun Yoo ◽  
Se Young Han ◽  
...  
Keyword(s):  
Quality Control ◽  
Analytical Method ◽  
Acid Content ◽  
Oleanonic Acid ◽  
Reliable Analytical Method

scholarly journals Anti-diabetes Constituents in Leaves of Smallanthus sonchifolius

2010 ◽  
Vol 5 (1) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Xiang Zheng ◽  
He Fan ◽  
Kang Ting-Guo ◽  
Dou De-Qiang ◽  
Gai Kuo ◽  
...  
Keyword(s):  
Quality Control ◽  
Chlorogenic Acid ◽  
Caffeic Acid ◽  
Analytical Method ◽  
Inhibitory Effect ◽  
Hplc Method ◽  
Smallanthus Sonchifolius ◽  
Rp Hplc

The inhibitory effect of smallanthaditerpenic acids A, B, C and D previously isolated from leaves of Smallanthus sonchifolius (yacon) on α-glucosidase were examined and their IC50 were determined to be 0.48 mg/mL, 0.59 mg/mL, 1.00 mg/mL, and 1.17 mg/mL respectively. In addition, a rapid, reliable RP-HPLC method for the analysis of chlorogenic acid, caffeic acid, and smallanthaditerpenic acids A and C in yacon leaves was established, and the variation in their contents in leaves from plants cultivated in different places and collected at different times of the year were compared. The established analytical method for determining smallanthaditerpenic acids A and C, chlorogenic acid and caffeic acid presented good results and could be used as a method for the quality control of S. sonchifolius leaves.

Development and Validation of an Analytical Method Readily Applicable for Quality Control of Tabebuia impetiginosa (Taheebo) Ethanolic Extract

2018 ◽  
Vol 101 (3) ◽  
pp. 695-700 ◽  
Author(s):  
Yan Jin ◽  
Kyung Min Jeong ◽  
Jeongmi Lee ◽  
Jing Zhao ◽  
Su-Young Choi ◽  
...  
Keyword(s):  
Quality Control ◽  
Analytical Method ◽  
Ethanolic Extract ◽  
Development And Validation

Determination of morphine and its metabolites in the biological samples: an updated review

Bioanalysis ◽  
2020 ◽  
Vol 12 (16) ◽  
pp. 1161-1194
Author(s):  
Roghayeh Amini ◽  
Elaheh Rahimpour ◽  
Abolghasem Jouyban
Keyword(s):  
Analytical Method ◽  
Biological Samples ◽  
Opioid Analgesic ◽  
Individual Variability ◽  
Active Metabolites ◽  
Analytical Research ◽  
Reliable Analytical Method ◽  
Selection Of

Morphine (MO) as an opioid analgesic is used for the treatment of moderate-to-severe pains, particularly cancer-related pains. Pharmacologic studies on MO are complicated due to drugs binding to the protein or metabolization to active metabolites, and even inter-individual variability. This necessitates the selection of a reliable analytical method for monitoring MO and the concentrations of its metabolites in the biological samples for the pharmacokinetic or pharmacodynamic investigations. Therefore, this study was conducted to review all the analytical research carried out on MO and its metabolites in the biological samples during 2007–2019 as an update to the study by Bosch et al. (2007).

scholarly journals IMPROVED ANALYTICAL METHOD FOR ESTIMATION OF ESSENTIAL OIL IN DRUG OINTMENT THROUGH RAPID STATIC CHROMATOGRAPHY HEADSPACE FOR QUALITY CONTROL ANALYSIS

2018 ◽  
Vol 11 (5) ◽  
pp. 290
Author(s):  
Dhir Nk ◽  
Joshi M ◽  
Kaur V
Keyword(s):  
Quality Control ◽  
Essential Oil ◽  
Analytical Method ◽  
Present Method ◽  
Control Analysis ◽  
Sample Treatment ◽  
Elution Time ◽  
Product Release ◽  
Quality Control Analysis ◽  
Quality Control Testing

Objective: The objective for new methodology was to develop a rapid analytical method for drug quantification in ointment samples and eliminate the usage of hazardous solvents in the sample and standard preparation, less elution time of component of interest to sustained green chemistry applications.Methods: Headspace (HS) chromatography was used along with gas chromatography (GC) having direct sample treatment with the help of calibration slope method.Results: All essential oil (EO) was well separated from each other and eluted 1.6 times faster from traditional classical GC method. The present method does not require any hazardous solvents for sample preparation. Conclusion: This method provides the accurate and precise results for EO added in ointment samples and can be used for routine quality control testing before releasing the final product release for the consumers.

Development of analytical method for the quality control of the fruit bark of Punica granatum L. (pomegranate) and antichemotatic activity of extract and rich fraction in punicalagins

2018 ◽  
Vol 33 (2) ◽  
pp. e4393 ◽  
Author(s):  
Bruno Alonso Sleifer ◽  
Melissa Schwanz ◽  
Leticia Jacobi Danielli ◽  
Miriam Anders Apel ◽  
Amélia Teresinha Henriques
Keyword(s):  
Quality Control ◽  
Analytical Method ◽  
Punica Granatum ◽  
Punica Granatum L

Cr(vi) soil analytical method: A reliable analytical method for extracting and quantifying Cr(vi) in soils

1997 ◽  
Vol 6 (6) ◽  
pp. 581-593 ◽  
Author(s):  
Rock J. Vitale ◽  
George R. Mussoline ◽  
John C. Petura ◽  
Bruce R. James
Keyword(s):  
Analytical Method ◽  
Reliable Analytical Method

scholarly journals Simultaneous analysis of major ingredients of Gardenia fruit by HPLC-MS/TQMS method

2017 ◽  
Vol 17 (43) ◽  
pp. 34-37
Author(s):  
M Galaqin ◽  
K Uwai ◽  
M Yuguchi ◽  
T Iwasa
Keyword(s):  
Quality Control ◽  
Quantitative Analysis ◽  
Flow Rate ◽  
Analytical Method ◽  
Mobile Phase ◽  
Gradient Elution ◽  
Simultaneous Analysis ◽  
Average Content ◽  
Ultrapure Water ◽  
Crude Drugs

An efficient, accurate HPLC-MS/TQMS method was introduced for the quantitative/qualitative simultaneous analysis of main ingredients, namely geniposide and genipingentiobioside, in the Gardenia fruit. The separation was successfully obtained using a C8 (100mm×2.1mm, 5μm, 30°C) column by gradient elution with ultrapure water as mobile phase, where flow rate was set to 0.2 ml/min and detection wavelength at 240 nm. The analytical method was validated and the quantification of active compounds, namely genipingentiobioside and gardenoside, was performed. Linearity, precision, repeatability, stability and recovery were also reported. The quantitative analysis revealed that both main ingredients as geniposide and genipingentiobioside have performed a good linear relationship in 0.1-100 mg/ml concentration range (r=1.00000 and r =0.99998). The average content was measured to be 4.842% with RSD 0.96% for geniposide and 1.1976% with RSD 0.47% for genipingentiobioside in the Gardenia fruit. Accordingly, this method would be feasible for the quantity and quality control of crude drugs.

Sign in / Sign up

Export Citation Format

Share Document