Acid-degradable gadolinium-based nanoscale coordination polymer: A potential platform for targeted drug delivery and potential magnetic resonance imaging

Nano Research ◽  
2017 ◽  
Vol 11 (2) ◽  
pp. 929-939 ◽  
Author(s):  
Zhimei He ◽  
Penghui Zhang ◽  
Yan Xiao ◽  
Jingjing Li ◽  
Fang Yang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Coordination Polymer ◽  
Targeted Drug Delivery ◽  
Resonance Imaging ◽  
Targeted Drug ◽  
Nanoscale Coordination Polymer

scholarly journals Gd3+ Doped CoFe2O4 Nanoparticles for Targeted Drug Delivery and Magnetic Resonance Imaging

2021 ◽  
Vol 7 (4) ◽  
pp. 47
Author(s):  
Fatima Javed ◽  
Muhammad Asad Abbas ◽  
Muhammad Imran Asad ◽  
Naveed Ahmed ◽  
Nauman Naseer ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Targeted Drug Delivery ◽  
Sol Gel ◽  
Resonance Imaging ◽  
Sustained Drug Release ◽  
Auto Combustion ◽  
Eudragit E100 ◽  
Targeted Drug

Nanoparticles of CoGdxFe2 − xO4 (x = 0%, 25%, 50%) synthesized via sol–gel auto combustion technique and encapsulated within a polymer (Eudragit E100) shell containing curcumin by single emulsion solvent evaporation technique were formulated in this study. Testing of synthesized nanoparticles was carried out by using different characterization techniques, to investigate composition, crystallinity, size, morphology, surface charge, functional groups and magnetic properties of the samples. The increased hydrophilicity resulted in sustained drug release of 90.6% and 95% for E1(CoGd0.25Fe1.75O4) and E2(CoGd0.50Fe1.5O4), respectively, over a time span of 24 h. The relaxivities of the best-chosen samples were measured by using a 3T magnetic resonance imaging (MRI) machine, and a high r2/r1 ratio of 43.64 and 23.34 for composition E1(CoGd0.25Fe1.75O4) and E2(CoGd0.50Fe1.5O4) suggests their ability to work as a better T2 contrast agent. Thus, these novel synthesized nanostructures cannot only enable MRI diagnosis but also targeted drug delivery.

scholarly journals Fabrication of a hyaluronic acid conjugated metal organic framework for targeted drug delivery and magnetic resonance imaging

RSC Advances ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 6581-6589 ◽  
Author(s):  
Fangpeng Shu ◽  
Daojun Lv ◽  
Xian-Lu Song ◽  
Bin Huang ◽  
Chong Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Magnetic Resonance ◽  
Targeted Drug Delivery ◽  
Metal Organic Framework ◽  
Resonance Imaging ◽  
One Pot ◽  
Metal Organic ◽  
Targeted Drug

DOX-doped MOF nanoparticles were prepared via a one-pot reaction and successively anchored with Fe3+ and HA for simultaneous targeted drug delivery and MR imaging.

Magnetic Resonance Imaging-Visible and pH-Sensitive Polymeric Micelles for Tumor Targeted Drug Delivery

2014 ◽  
Vol 10 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Zuoquan Zhang ◽  
Qiquan Sun ◽  
Jinglian Zhong ◽  
Qihua Yang ◽  
Hao Li ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Targeted Drug Delivery ◽  
Polymeric Micelles ◽  
Ph Sensitive ◽  
Resonance Imaging ◽  
Targeted Drug

A Smart Nanoassembly for Multistage Targeted Drug Delivery and Magnetic Resonance Imaging

2014 ◽  
Vol 24 (23) ◽  
pp. 3612-3620 ◽  
Author(s):  
Zhenhua Li ◽  
Kai Dong ◽  
Sa Huang ◽  
Enguo Ju ◽  
Zhen Liu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Targeted Drug Delivery ◽  
Resonance Imaging ◽  
Targeted Drug

scholarly journals New advances on Au–magnetic organic hybrid core–shells in MRI, CT imaging, and drug delivery

RSC Advances ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 6517-6525
Author(s):  
Fatemeh Mohajer ◽  
Ghodsi Mohammadi Ziarani ◽  
Alireza Badiei
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Targeted Drug Delivery ◽  
Magnetic Storage ◽  
Resonance Imaging ◽  
Organic Hybrid ◽  
Storage Media ◽  
Targeted Drug ◽  
Magnetic Storage Media

Magnetic nanoparticles have been studied for scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging, biolabelling, separation of biomolecules, and magnetic-targeted drug delivery.

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