scholarly journals New advances on Au–magnetic organic hybrid core–shells in MRI, CT imaging, and drug delivery

RSC Advances ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 6517-6525
Author(s):  
Fatemeh Mohajer ◽  
Ghodsi Mohammadi Ziarani ◽  
Alireza Badiei

Magnetic nanoparticles have been studied for scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging, biolabelling, separation of biomolecules, and magnetic-targeted drug delivery.

NANO ◽  
2010 ◽  
Vol 05 (05) ◽  
pp. 245-270 ◽  
Author(s):  
AIGUO WU ◽  
PING OU ◽  
LEYONG ZENG

In this review, the applications of magnetic nanoparticles in biomedicine are summarized and introduced in three parts. (1) A short description of magnetic nanoparticles is explained. (2) Applications of magnetic nanoparticles in biomedicine are summarized. In biology, new progress of the magnetic separation techniques based on magnetic nanoparticles is discussed. In medicine, the magnetic nanoparticles as therapeutic agents (particularly as a hyperthermia agent, a targeted drug delivery carrier, and a magnetofection agent) as well as contrast agents in magnetic resonance imaging (MRI) are explained in detail. (3) A discussion and remarking conclusion of magnetic nanoparticles in biomedical applications are described. Finally, a perspective of the magnetic nanoparticles in biomedicine in future is also described.


2021 ◽  
Vol 7 (4) ◽  
pp. 47
Author(s):  
Fatima Javed ◽  
Muhammad Asad Abbas ◽  
Muhammad Imran Asad ◽  
Naveed Ahmed ◽  
Nauman Naseer ◽  
...  

Nanoparticles of CoGdxFe2 − xO4 (x = 0%, 25%, 50%) synthesized via sol–gel auto combustion technique and encapsulated within a polymer (Eudragit E100) shell containing curcumin by single emulsion solvent evaporation technique were formulated in this study. Testing of synthesized nanoparticles was carried out by using different characterization techniques, to investigate composition, crystallinity, size, morphology, surface charge, functional groups and magnetic properties of the samples. The increased hydrophilicity resulted in sustained drug release of 90.6% and 95% for E1(CoGd0.25Fe1.75O4) and E2(CoGd0.50Fe1.5O4), respectively, over a time span of 24 h. The relaxivities of the best-chosen samples were measured by using a 3T magnetic resonance imaging (MRI) machine, and a high r2/r1 ratio of 43.64 and 23.34 for composition E1(CoGd0.25Fe1.75O4) and E2(CoGd0.50Fe1.5O4) suggests their ability to work as a better T2 contrast agent. Thus, these novel synthesized nanostructures cannot only enable MRI diagnosis but also targeted drug delivery.


RSC Advances ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 6581-6589 ◽  
Author(s):  
Fangpeng Shu ◽  
Daojun Lv ◽  
Xian-Lu Song ◽  
Bin Huang ◽  
Chong Wang ◽  
...  

DOX-doped MOF nanoparticles were prepared via a one-pot reaction and successively anchored with Fe3+ and HA for simultaneous targeted drug delivery and MR imaging.


2014 ◽  
Vol 24 (23) ◽  
pp. 3612-3620 ◽  
Author(s):  
Zhenhua Li ◽  
Kai Dong ◽  
Sa Huang ◽  
Enguo Ju ◽  
Zhen Liu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document