Suppressive effects of the diethyl ether fraction from a brown alga Sargassum fusiforme on allergic and inflammatory reactions

2016 ◽  
Vol 82 (2) ◽  
pp. 369-377 ◽  
Author(s):  
Yoshimasa Sugiura ◽  
Yuichi Kinoshita ◽  
Mahiko Abe ◽  
Noboru Murase ◽  
Ryusuke Tanaka ◽  
...  
Keyword(s):  
Diethyl Ether ◽  
Brown Alga ◽  
Inflammatory Reactions ◽  
Sargassum Fusiforme ◽  
Ether Fraction

scholarly journals Extraction and Identification of Phlorotannins from the Brown Alga, Sargassum fusiforme (Harvey) Setchell

Marine Drugs ◽  
2017 ◽  
Vol 15 (2) ◽  
pp. 49 ◽  
Author(s):  
Yajing Li ◽  
Xiaoting Fu ◽  
Delin Duan ◽  
Xiaoyong Liu ◽  
Jiachao Xu ◽  
...  
Keyword(s):  
Brown Alga ◽  
Sargassum Fusiforme

scholarly journals Aktivitas Antioksidan Fraksi Dietileter Buah Mangga Arumanis (Mangifera indica L.) dengan Metode DPPH

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Dewi Andini Kunti Mulangsri ◽  
Aqnes Budiarti ◽  
Endah Novia Saputri
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Diethyl Ether ◽  
Mangifera Indica ◽  
Ethanol Extract ◽  
Natural Antioxidants ◽  
Antioxidant Systems ◽  
Ic50 Value ◽  
Dpph Method ◽  
Ether Fraction

ABSTRAK Sistem antioksidan merupakan bagian dari sistem kekebalan tubuh yang mampu menghambat reaktifitas radikal bebas. Sumber alami antioksidan salah satunya adalah buah yaitu buah mangga Arumanis. Proses fraksinasi dengan pelarut dietileter dilakukan untuk menyari senyawa-senyawa yang bersifat semipolar yang diharapkan memiliki potensi sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan fraksi dietil eter ekstrak etanol buah mangga arumanis (Mangifera indica L.) dengan Metode DPPH. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 70%, kemudian dipartisi cair-cair menggunakan pelarut dietil eter. Penentuan aktivitas antioksidan menggunakan metode DPPH dengan membuat seri konsentrasi fraksi dietil eter ekstrak etanol buah mangga Arumanis yaitu 12,5; 25; 50 dan 100ppm. Vitamin C digunakan sebagai larutan pembanding dengan seri konsentrasi 0,625; 1,25; 2,5 dan 5 ppm. Hasil penelitian menunjukkan bahwa fraksi dietil eter ekstrak etanol buah mangga arumanis memiliki aktivitas antioksidan dengan nilai IC50 sebesar 75,22 ppm dan 1,18 ppm untuk Vitamin C. Fraksi dietileter ekstrak etanol buah mangga Arumanis memiliki potensi lemah sebagai antioksidan jika dibandingkan dengan Vitamin C. Kata Kunci: antioksidan, fraksi dietileter, buah mangga arumanis, Mangifera indica, DPPH ABSTRACT Antioxidant systems are part of the immune system which is able to inhibit the reactivity of free radical. Source of natural antioxidants is a fruit that is mango Arumanis. Process of fractionation with solvent diethylether to extraction the compounds semipolar and expected to have potential as antioxidants. This study aims to determine the antioxidant activity of diethyl ether fraction of ethanol extract Arumanis mango (Mangifera indica L.) with DPPH method. Extraction used ethanol 70% by maceration method, then partitioned using a liquid-liquid partition with diethylether as a solvent. Determination of antioxidant activity using DPPH method with a series of concentrations of diethyl ether fraction of ethanol extract Arumanis mango ie 12.5; 25; 50 and 100ppm. Vitamin C used as a reference solution with a concentration series of 0,625; 1.25; 2.5 and 5 ppm. The results showed that the diethyl ether fraction of ethanol extract Arumanis mango have antioxidant activity with IC50 value of 7.22 ppm and 1.18 ppm for Vitamin C. Diethylether fraction of ethanol extract Arumanis mango has weak potential as a antioxidant, if compared with Vitamin C. Keywords: Antioxidants, diethylether fractions, arumanis mango fruit, Mangifera indica, DPPH.

scholarly journals Histological changes in the orbital region of rats after orbital puncture

1992 ◽  
Vol 26 (1) ◽  
pp. 53-58 ◽  
Author(s):  
H. van Herck ◽  
V. Baumans ◽  
N. R. van der Craats ◽  
A. P. M. Hesp ◽  
G. W. Meijer ◽  
...  
Keyword(s):  
Diethyl Ether ◽  
Random Order ◽  
Harderian Gland ◽  
The Other ◽  
Histological Changes ◽  
Inflammatory Reactions ◽  
Ether Anaesthesia ◽  
Orbital Region ◽  
Diethyl Ether Anaesthesia

To contribute to the assessment of the degree of discomfort in rats after orbital puncture, we have examined the histological changes in the intra-orbital tissues caused by this technique of blood sampling. Orbits were studied from rats euthanized either within 1 min, 4 days, 28 days or 56 days after puncture while under diethyl-ether anaesthesia. The techniques of 2 animal technicians were compared, one using a broken haematocrit capillary and the other using an intact Pasteur's pipette. Non-punctured orbits served as controls. Microscopic slides containing the eye in situ at 2 horizontal levels in the orbital region were examined for 37 parameters; the slides were scored blind and in random order. Orbital puncture caused haemorrhages in the puncture track and, depending on the technique used, also in the periosteum. Four days after puncture, inflammatory reactions were present in the puncture track. Depending on the technique of puncture, these reactions were also seen in the eye muscles and periosteum or in the Harderian gland. Within 4 weeks after puncture, the lesions had healed without detectable scars. The different histological effects of the 2 techniques of orbital puncture are discussed in the light of the characteristics of these techniques.

Cytotoxic Hydroazulene Diterpenes from the Brown Alga Dictyota dichotoma

2003 ◽  
Vol 58 (1-2) ◽  
pp. 17-22 ◽  
Author(s):  
Sahar R. Gedara ◽  
Osama B. Abdel-Halim ◽  
Saleh H. El-Sharkawy ◽  
Osama M. Salama ◽  
Thomas W. Shier ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Cytotoxic Activity ◽  
Red Sea ◽  
Brown Alga ◽  
Alcoholic Extract ◽  
Dictyota Dichotoma ◽  
Ether Fraction ◽  
Steroidal Compound ◽  
Chemical Correlation ◽  
Physical And Chemical

Two new hydroazulenoid (prenyl guaiane) diterpenes, dictyone acetate (2) and 3,4-epoxy 13-hydroxy pachydictyol A (4) were isolated from the petroleum ether fraction of the alcoholic extract of the brown alga, Dictyota dichotoma (Hudson) Lamouroux, which was collected from the Red Sea coasts at Hurgada, Egypt, together with three known ones, pachydictyol A (1), dictyone (3) and 11-hydroxypachydictyol A (dictyol E) (5). In addition, the steroidal compound, stigmasta-5,(E)-24(28)-dien-3-β-ol (fucosterol) (6) was also isolated. The structures of the isolated compounds have been determined on the basis of spectroscopic evidences as well as physical and chemical correlation with known compounds. Compounds 1, 2, 3 and 5 showed moderate cytotoxic activity

Daucus carota Pentane/Diethyl Ether Fraction Inhibits Motility and Reduces Invasion of Cancer Cells

Chemotherapy ◽  
2014 ◽  
Vol 60 (5-6) ◽  
pp. 302-309 ◽  
Author(s):  
Perla Zgheib ◽  
Costantine F. Daher ◽  
Mohamad Mroueh ◽  
Anita Nasrallah ◽  
Robin I. Taleb ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Diethyl Ether ◽  
Daucus Carota ◽  
Ether Fraction

scholarly journals Identification of active compounds and antifungal activity of Toona sinensis leaves fractions against wood rot fungi

2018 ◽  
Vol 19 (4) ◽  
pp. 1313-1318 ◽  
Author(s):  
RIZKI RABECA ELFIRTA ◽  
SYAMSUL FALAH ◽  
DIMAS ANDRIANTO ◽  
TIEN LASTINI
Keyword(s):  
Antifungal Activity ◽  
Diethyl Ether ◽  
Methanol Extract ◽  
Growth Direction ◽  
Active Compounds ◽  
Toona Sinensis ◽  
Abnormal Growth ◽  
Ether Fraction ◽  
Wood Rot Fungi ◽  
Layer Chromatography

Elfirta RR, Falah S, Andrianto D, Lastini T. 2018. Identification of active compounds and antifungal activity of Toona sinensisleaves fractions against wood rot fungi. Biodiversitas 19: 1313-1318. Inhibitory activities of surian or toon (Toona sinensis) leavesfraction origin Sumedang, West Java, Indonesia against wood rot fungi (Ganoderma boninense IPBCC 10.658, Trametes versicolorInaCC F200, and Phanerochaete chrysosporium IPBCC 93.259) were studied. The samples were macerated using methanol andacetone. The results of brine shrimp lethality test (BSLT) showed that the methanol extract had the highest cytotoxicity of LC50 at 29.76μg/mL and inhibit the growth of G. boninense (27.78%), T. versicolor (79.26%) and P. chrysosporium (81.11%). The methanol extractwas then subsequently fractionated using n-hexane, diethyl ether, and ethyl acetate respectively. The diethyl ether fraction was found tohave the highest inhibitory activity against T. versicolor (46.30%) and P. chrysosporium (81.11%). This fraction was further separatedusing column chromatography and analyzed using thin layer chromatography (TLC), which gave six fractions. Antifungal test exhibitedthat fraction 5 had the highest antifungal properties against T. versicolor (74.07%) and P. chrysosporium (80.37%). Inhibition of P.chrysosporium resulted in abnormal growth of hyphae morphology as indicated by changes in its growth direction and excessive hyphaebranching. Additionally, the results of LC-MS/MS experiment indicated toon leaves fraction 5 which contains N-[2- (DGlucopyranosyloxy)ethyl]-2-hydroxy-N-[2hydroxy3 (octadecyloxy) propyl] butanamide dan Brucine compounds that were regarded as theantifungal compounds.

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