Synthesis, Characterization of Erythromycin Propionate Core-Based Star Poly(ether urethane)s and Their Antibacterial Properties

This paper concerns the physicochemical properties of chitosan/phenolic acid thin films irradiated by ultraviolet radiation with wavelengths between 200 and 290 nm (UVC) light. We investigated the preparation and characterization of thin films based on chitosan (CTS) with tannic (TA), caffeic (CA) and ferulic acid (FA) addition as potential food-packaging materials. Such materials were then exposed to the UVC light (254 nm) for 1 and 2 h to perform the sterilization process. Different properties of thin films before and after irradiation were determined by various methods such as Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), atomic force microscopy (AFM), differential scanning calorimeter (DSC), mechanical properties and by the surface free energy determination. Moreover, the antimicrobial activity of the films and their potential to reduce the risk of contamination was assessed. The results showed that the phenolic acid improving properties of chitosan-based films, short UVC radiation may be used as sterilization method for those films, and also that the addition of ferulic acid obtains effective antimicrobial activity, which have great benefit for food packing applications.

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Antibacterial Properties of Biofilm Schiff Base Derived from Dialdehyde Cellulose and Chitosan

Indonesian Journal of Chemistry ◽

10.22146/ijc.34721 ◽

2019 ◽

Vol 19 (2) ◽

pp. 405

Author(s):

Agung Pratama ◽

Firman Sebayang ◽

Rumondang Bulan Nasution

Keyword(s):

Tensile Strength ◽

Antibacterial Activity ◽

Schiff Base ◽

Antibacterial Properties ◽

Oxidized Cellulose ◽

Natural Polymers ◽

Dialdehyde Cellulose ◽

Ft Ir ◽

Ir Analysis

Cellulose and chitosan are natural polymers that have been used as biocomposite. The aim of this research is to obtain biofilms from chitosan and oxidized cellulose crosslinks. This research is divided into three steps, i.e., isolation of cellulose from oil palm trunk and oxidation of cellulose using NaIO4 (0.2; 0.4; 0.6; 0.8; 1.0 mg/mL) to obtain dialdehyde cellulose (DAC), crosslink of oxidized cellulose with chitosan (DD = 72.85%) to obtain biofilm of chitosan/DAC (CDAC), and characterization of biofilms. The crosslinked reaction was confirmed by FT-IR analysis that showed the spectrum of Schiff base C=N group at 1651 cm–1. Tensile strength increased gradually when the NaIO4 concentration used was 0.2–0.6 mg/mL, but after those concentrations, the tensile strength slightly decreased. The morphology analysis showed that CDAC had smoother morphology than DAC, which was shown rough and showed some particle indicated the presence of unreacted cellulose. CDAC biofilms that prepared with 1.0 mg/mL NaIO4 showed the greatest antibacterial activity.

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Production and Characterization of Keratin/Tragacanth Gum Nanohydrogels for Drug Delivery in Medical Textiles

Frontiers in Materials ◽

10.3389/fmats.2021.720385 ◽

2021 ◽

Vol 8 ◽

Author(s):

Nazanin Mansouri Shirazi ◽

Niloofar Eslahi ◽

Adeleh Gholipour-Kanani

Keyword(s):

Disulfide Bonds ◽

Antibacterial Properties ◽

Antimicrobial Properties ◽

Spherical Shape ◽

Herbal Extract ◽

Minimum Size ◽

Mechanical Resistance ◽

Tragacanth Gum ◽

Medical Textiles

Keratin protein has been applied for biomedical applications due to its biocompatibility, biodegradability, mechanical resistance, and bioavailability. Tragacanth gum (TG) as a polysaccharide-based biopolymer has wound healing and antimicrobial properties. In this study, keratin was extracted from protein-based chicken feather by using reduction hydrolysis (sodium sulfide), and nanogels of keratin and TG composites at different ratios were produced by using the chemical cross-linking method. Then, cinnamon (5 and 10%) as an antibacterial herbal extract was added to the nanogels and coated on cotton fabric. The morphology and size of the composite nanogels, chemical structure, biological, and antibacterial properties were evaluated. According to DLS results, TGK2:1 (ratio of TG to keratin = 2:1) had the minimum size (80 nm) and PDI (0.1), and therefore, this sample was chosen as the optimum one. FESEM and TEM images showed the semi-spherical shape of the produced nanogels. FTIR spectra revealed the possible hydrogen bonding between the components, and the formation of disulfide bonds after the addition of hydrogen peroxide was confirmed by XPS. After loading cinnamon into the nanogels, an increase in size was observed from 80 nm for free-nanogel to 85 and 105 nm for 5 and 10% extract-loaded nanogels, respectively. Besides, more cinnamon was released from the treated fabrics by increasing time and cinnamon concentration. The antibacterial test exhibited good antibacterial properties against both Gram-positive and Gram-negative bacteria. Finally, MTT assay approved the biocompatibility of the produced nanogels for potential use in medical textiles.

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NOVEL COMPOSITE OF SILVER-BACTERIAL CELLULOSE (Ag-BC) FROM SIWALAN SAP (Borassus flabellifer) AND ITS ANTIBACTERIAL ACTIVITY

Jurnal Teknologi ◽

10.11113/jurnalteknologi.v83.14363 ◽

2020 ◽

Vol 83 (1) ◽

pp. 19-25

Author(s):

Suntini Suntini ◽

Anastasia Wheni Indrianingsih ◽

Harjono Harjono

Keyword(s):

Antibacterial Activity ◽

Bacterial Cellulose ◽

Antibacterial Properties ◽

Reduction Process ◽

Diffusion Method ◽

Natural Material ◽

Gram Positive Bacteria ◽

Antibacterial Assay ◽

Natural Composite

Recently, a wound healing from natural composite with excellent properties is in a high demand. In this study, a novel composite of bacterial cellulose made from Siwalan sap (Borassus flabellifer) was achieved. Siwalan is a common plant in Java Island of Indonesia and the application is very limited for beverage only. This study aims to determine the effect of the AgNO3/NaBH4 concentration ratio in the development of Ag-BC composites and its antibacterial properties from Siwalan sap. Ag-BC composites were prepared by impregnating the silver solution into the BC matrix through the reduction process with NaBH4. Characterization of Ag-BC composites conducted using Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray (EDX). Antibacterial assay was performed using disc diffusion method against Salmonella typhimurium (Gram-negative) and Staphylococcus aureus (Gram-positive) bacteria. The characterization of Ag-BC composite shows the nanostructure of BC with a length of fiber around 35-60 nm in width. The SEM-EDX micrograph showed that silver particles were impregnated into the BC matrix. Antibacterial activity test results showed that the Ag-BC composite had the ability to inhibit the bacteria S. typhimurium and S. aureus with good inhibition. This result showed the potential application of Ag-BC composite from Siwalan plant as a natural material for medical and pharmaceutical purpose, especially as an antibacterial agent.

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Phytochemical Investigation of the Australian Lichens Ramalina glaucescens and Xanthoria parietina

Natural Product Communications ◽

10.1177/1934578x0900400717 ◽

2009 ◽

Vol 4 (7) ◽

pp. 1934578X0900400 ◽

Cited By ~ 1

Author(s):

Daniel A. Dias ◽

Sylvia Urban

Keyword(s):

Antibacterial Properties ◽

Usnic Acid ◽

2D Nmr ◽

Antibacterial Activities ◽

2D Nmr Spectroscopy ◽

Full Characterization ◽

Phytochemical Investigation ◽

Xanthoria Parietina ◽

Shift Assignment

Phytochemical investigation of the Australian lichen, Ramalina glaucescens resulted in the isolation of a new halogenated depside, 5-chlorosekikaic acid 5, together with (+)-usnic acid 1, sekikaic acid 2, atranorin 6 and parietin 7, the latter of which was isolated from the associated (co-occurring) lichen, X. parietina. Compound 5 is suspected to be an artifact of the isolation procedure. All structures were assigned using spectroscopic methods and mass spectrometry. In addition to the full characterization of 5, this report represents the first application of 2D NMR spectroscopy to complete the unequivocal chemical shift assignment for compounds 2 and 7. Compounds 1-2 and 5-7 all displayed varying degrees of antitumor activity (ranging from an IC50 of 15 μM to >44 μM) with compounds 1, 2 and 5 also displaying antibacterial properties. Of these, (+)-usnic acid 1 displayed the most significant antitumor and antibacterial activities.

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Synthesis and characterization of quaternized agar in KOH/urea aqueous solution

New Journal of Chemistry ◽

10.1039/d0nj03412f ◽

2020 ◽

Vol 44 (39) ◽

pp. 17062-17069

Author(s):

Fuyuan Ding ◽

Yuye Zhong ◽

Shuping Wu ◽

Xinghai Liu ◽

Xiaobo Zou ◽

...

Keyword(s):

Aqueous Solution ◽

Antibacterial Properties ◽

Synthesis And Characterization ◽

Urea Aqueous Solution

Quaternized agar (QA) is synthesized in KOH/urea aqueous solution and shows low melting and gelling temperatures and antibacterial properties.

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Design, synthesis and characterization of copper-based coordination compounds with bidentate (N,N and N,O) ligands: reversible uptake of iodine, dye adsorption and assessment of their antibacterial properties

CrystEngComm ◽

10.1039/c8ce01348a ◽

2019 ◽

Vol 21 (2) ◽

pp. 251-262 ◽

Cited By ~ 10

Author(s):

Azizolla Beheshti ◽

Elham Sadat Mousavi Fard ◽

Maciej Kubicki ◽

Peter Mayer ◽

Carmel T. Abrahams ◽

...

Keyword(s):

Coordination Compounds ◽

Copper Complexes ◽

Antibacterial Properties ◽

Dye Adsorption ◽

Antibacterial Activities ◽

Synthesis And Characterization ◽

Design Synthesis ◽

Iodine Adsorption

This work presents the synthesis of close-packed copper complexes with an uncommon ability for dye and iodine adsorption and antibacterial activities.

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