Examination of Couple Stress Hybrid Nanoparticles (CuO-Cu/Blood) as a Targeted Drug Carrier with Magnetic Effects Through Porous Sheet

2021 ◽  
Author(s):  
Muhammad Jawad ◽  
Arshad Khan ◽  
Syed Azhar Ali Shah
Keyword(s):  
Couple Stress ◽  
Drug Carrier ◽  
Hybrid Nanoparticles ◽  
Porous Sheet ◽  
Magnetic Effects ◽  
Targeted Drug

An Integrative Folate-Based Metal Complex Nanotube as a Potent Antitumor Nanomedicine as Well as an Efficient Tumor-Targeted Drug Carrier

2016 ◽  
Vol 27 (12) ◽  
pp. 2863-2873 ◽  
Author(s):  
Li X. Liu ◽  
Bing X. Li ◽  
Qi Y. Wang ◽  
Zhi P. Dong ◽  
Hong M. Li ◽  
...  
Keyword(s):  
Metal Complex ◽  
Drug Carrier ◽  
Targeted Drug

Biotinylated carboxymethyl chitosan/CaCO3 hybrid nanoparticles for targeted drug delivery to overcome tumor drug resistance

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69083-69093 ◽  
Author(s):  
Jin-Long Wu ◽  
Xiao-Yan He ◽  
Pei-Yuan Jiang ◽  
Meng-Qing Gong ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Tumor Cells ◽  
Targeted Drug Delivery ◽  
Carboxymethyl Chitosan ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Tumor Drug Resistance ◽  
Anti Cancer ◽  
Targeted Drug

A tumor targeted nano-sized self-assembled drug delivery system could efficiently co-deliver an anti-cancer drug and a drug resistance inhibitor to tumor cells and achieve an improved therapeutic efficiency through inhibition of P-gp function.

Ultrasound-mediated targeted drug delivery with a novel cyclodextrin-based drug carrier by mechanical and thermal mechanisms

2013 ◽  
Vol 170 (3) ◽  
pp. 316-324 ◽  
Author(s):  
Dana Gourevich ◽  
Osnat Dogadkin ◽  
Alexander Volovick ◽  
Lijun Wang ◽  
Jallal Gnaim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Drug Carrier ◽  
Targeted Drug

Polymeric Micelles Modified by Folate-PEG-Lipid for Targeted Drug Delivery to Cancer Cells In Vitro

2008 ◽  
Vol 8 (6) ◽  
pp. 3085-3090 ◽  
Author(s):  
Akihiro Hayama ◽  
Tatsuhiro Yamamoto ◽  
Masayuki Yokoyama ◽  
Kumi Kawano ◽  
Yoshiyuki Hattori ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cellular Uptake ◽  
Laser Scanning ◽  
Polymeric Micelles ◽  
Folate Receptor ◽  
Drug Carrier ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Kb Cells ◽  
Targeted Drug

A novel technique was developed for the formation of ligand-targeted polymeric micelles that can be applicable to various ligands. For tumor-specific drug delivery, camptothecin (CPT)-loaded polymeric micelles were modified by folate to produce a folate-receptor-targeted drug carrier. Folate-linked PEG5000-distearoylphosphatidylethanolamine (folate-PEG5000-DSPE) was added when preparations of drug-loaded polymeric micelles, resulting in folate ligands exposed to the surface. Folate-modified CPT-loaded polymeric micelles (F-micelle) were evaluated by measuring cellular uptake using a flow cytometer, fluorescence microscopy, and confocal laser scanning microscopy, and by cytotoxicity measurement. The results revealed that F-micelle showed higher cellular uptake in KB cells over-expressing folate receptor (FR) and higher cytotoxicity compared with non-folate modified CPT-loaded polymeric micelles (plain micelles) in KB cells, but not in FR-negative HepG2 cells. This result indicated that polymeric micelles were successfully modified by the folate-linked lipid.

Modification of graphene oxide by a facile coprecipitation method and click chemistry for use as a drug carrier

RSC Advances ◽  
2014 ◽  
Vol 4 (54) ◽  
pp. 28807-28813 ◽  
Author(s):  
Guoqiang Xu ◽  
Pengwu Xu ◽  
Dongjian Shi ◽  
Mingqing Chen
Keyword(s):  
Graphene Oxide ◽  
Click Chemistry ◽  
Drug Carrier ◽  
Coprecipitation Method ◽  
Ternary Composite ◽  
Targeted Drug

A graphene oxide based ternary composite was synthesized for targeted drug carrier.

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