Modification of graphene oxide by a facile coprecipitation method and click chemistry for use as a drug carrier

RSC Advances ◽  
2014 ◽  
Vol 4 (54) ◽  
pp. 28807-28813 ◽  
Author(s):  
Guoqiang Xu ◽  
Pengwu Xu ◽  
Dongjian Shi ◽  
Mingqing Chen
Keyword(s):  
Graphene Oxide ◽  
Click Chemistry ◽  
Drug Carrier ◽  
Coprecipitation Method ◽  
Ternary Composite ◽  
Targeted Drug

A graphene oxide based ternary composite was synthesized for targeted drug carrier.

Comprehensive Review on Graphene Oxide for Use in Drug Delivery System

2020 ◽  
Vol 27 (22) ◽  
pp. 3665-3685 ◽  
Author(s):  
Muhammad Daniyal ◽  
Bin Liu ◽  
Wei Wang
Keyword(s):  
Graphene Oxide ◽  
Surface Area ◽  
Biomedical Applications ◽  
Drug Transport ◽  
Drug Carrier ◽  
Drug Loading ◽  
Anti Cancer ◽  
Targeted Drug ◽  
Nano Graphene ◽  
High Drug Loading

Motivated by the accomplishment of carbon nanotubes (CNTs), graphene and graphene oxide (GO) has been widely investigated in the previous studies as an innovative medication nanocarrier for the loading of a variety of therapeutics as well as anti-cancer medications, poor dissolvable medications, antibiotics, antibodies, peptides, DNA, RNA and genes. Graphene provides the ultra-high drug-loading efficiency due to the wide surface area. Graphene and graphene oxide have been widely investigated for biomedical applications due to their exceptional qualities: twodimensional planar structure, wide surface area, chemical and mechanical constancy, sublime conductivity and excellent biocompatibility. Due to these unique qualities, GO applications provide advanced drug transports frameworks and transports of a broad range of therapeutics. In this review, we discussed the latest advances and improvements in the uses of graphene and GO for drug transport and nanomedicine. Initially, we have described what is graphene and graphene oxide. After that, we discussed the qualities of GO as a drug carrier, utilization of GO in drug transport applications, targeted drug transport, transport of anticancer medications, chemical control medicine releasee, co-transport of different medications, comparison of GO with CNTs, nano-graphene for drug transport and at last, we have discussed the graphene toxicity. Finally, we draw a conclusion of current expansion and the potential outlook for the future.

scholarly journals Extended Release of Metronidazole Drug Using Chitosan/Graphene Oxide Bionanocomposite Beads as the Drug Carrier

ACS Omega ◽  
2021 ◽  
Author(s):  
Gyanendra Kumar ◽  
Karan Chaudhary ◽  
Navin Kumar Mogha ◽  
Arun Kant ◽  
Dhanraj T. Masram
Keyword(s):  
Graphene Oxide ◽  
Extended Release ◽  
Drug Carrier

scholarly journals A SnO2QDs/GO/PPY ternary composite film as positive and graphene oxide/charcoal as negative electrodes assembled solid state asymmetric supercapacitor for high energy storage applications

RSC Advances ◽  
2021 ◽  
Vol 11 (45) ◽  
pp. 27801-27811
Author(s):  
M. Vandana ◽  
Y. S. Nagaraju ◽  
H. Ganesh ◽  
S. Veeresh ◽  
H. Vijeth ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Energy Storage ◽  
Solid State ◽  
Composite Film ◽  
High Energy ◽  
Asymmetric Supercapacitor ◽  
Ternary Composite ◽  
Negative Electrodes ◽  
Energy Storage Applications ◽  
High Energy Storage

Representation of the synthesis steps of SnO2QDs/GO/PPY ternary composites and SnO2QDs/GO/PPY//GO/charcoal asymmetric supercapacitor device.

Transferrin Modified Graphene Oxide for Glioma-Targeted Drug Delivery: In Vitro and in Vivo Evaluations

2013 ◽  
Vol 5 (15) ◽  
pp. 6909-6914 ◽  
Author(s):  
Guodong Liu ◽  
He Shen ◽  
Jinning Mao ◽  
Liming Zhang ◽  
Zhen Jiang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Targeted Drug Delivery ◽  
Modified Graphene Oxide ◽  
Targeted Drug ◽  
Modified Graphene

scholarly journals Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Typhonium giganteum Drugs

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Xiaohua Gu ◽  
Rui Cao ◽  
Fu Li ◽  
Yan Li ◽  
Hongge Jia ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Graphene Oxide ◽  
Targeted Delivery ◽  
Drug Carrier ◽  
Dual Function ◽  
Natural Environments ◽  
Scanning Calorimetry ◽  
Environment Friendly ◽  
A549 Lung ◽  
Scanning Electron

In this study, Typhonium giganteum containing dual-function nanofibers composed of poly(butylene carbonate), polylactic acid, and graphene oxide (PBC/PLA/GO) were successfully fabricated by electrospinning. The results from thermogravimetric analysis (TG), differential scanning calorimetry (DSC), and Fourier-transform infrared spectroscopy (FTIR) indicate that no interactions occurred between PBC and PLA. The nanofiber microstructure upon which graphene oxide was evenly distributed was studied by scanning electron microscopy (SEM) and showed good silk properties. The nanofibers can be used as a drug carrier since loaded Typhonium giganteum fibers possess excellent biocompatibility. Such nanofibers are effective in inhibiting the proliferation of A549 lung cancer cells, and thus they have potential for replacing chemotherapy-based treatments of lung cancer. In addition, the PBC/PLA/GO nanofibers degrade in physiological and natural environments, which is an important feature when engineering tissues and environment-friendly materials.

Fluorescent detection of copper(II) based on DNA-templated click chemistry and graphene oxide

Methods ◽  
2013 ◽  
Vol 64 (3) ◽  
pp. 299-304 ◽  
Author(s):  
Lifen Zhou ◽  
Qinpeng Shen ◽  
Peng Zhao ◽  
Bingbing Xiang ◽  
Zhou Nie ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Click Chemistry ◽  
Fluorescent Detection
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