scholarly journals Vulvar Melanoma: Molecular Characteristics, Diagnosis, Surgical Management, and Medical Treatment

2021 ◽  
Author(s):  
Christoph Wohlmuth ◽  
Iris Wohlmuth-Wieser
Keyword(s):  
Medical Treatment ◽  
Surgical Management ◽  
Molecular Characteristics ◽  
Vulvar Melanoma

Medical treatment of pulmonary hydatidosis: complications and surgical management

2004 ◽  
Vol 19 (12) ◽  
pp. 774-776 ◽  
Author(s):  
D. Keramidas ◽  
G. Mavridis ◽  
M. Soutis ◽  
A. Passalidis
Keyword(s):  
Medical Treatment ◽  
Surgical Management

scholarly journals Isolated Duodenal Crohn's Disease: A Case Report and a Review of the Surgical Management

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Faruk Karateke ◽  
Ebru Menekşe ◽  
Koray Das ◽  
Sefa Ozyazici ◽  
Pelin Demirtürk
Keyword(s):  
Crohn’S Disease ◽  
Case Report ◽  
Gastrointestinal Tract ◽  
Crohn's Disease ◽  
Medical Treatment ◽  
Immunosuppressive Therapy ◽  
Surgical Management ◽  
Surgical Intervention ◽  
Surgical Options ◽  
Crohn’S Diseases

Crohn's disease may affect any segment of the gastrointestinal tract; however, isolated duodenal involvement is rather rare. It still remains a complex clinical entity with a controversial management of the disease. Initially, patients with duodenal Crohn' s disease (DCD) are managed with a combination of antiacid and immunosuppressive therapy. However, medical treatment fails in the majority of DCD patients, and surgical intervention is required in case of complicated disease. Options for surgical management of complicated DCD include bypass, resection, or stricturoplasty procedures. In this paper, we reported a 33-year-old male patient, who was diagnosed with isolated duodenal Crohn’s diseases, and reviewed the surgical options in the literature.

The utility of sentinel lymph node biopsy in the surgical management of women with vulvar melanoma

2012 ◽  
Vol 125 ◽  
pp. S84 ◽  
Author(s):  
A. Nickles Fader ◽  
J. Ducie ◽  
N. Abu-Rustum ◽  
P. Escobar ◽  
C. Levenback ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Surgical Management ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Vulvar Melanoma

Bifocal pulmonary abscess in an infant and successful surgical management

2019 ◽  
Vol 27 (6) ◽  
pp. 498-500
Author(s):  
Saloua Ammar ◽  
Myriam Ben Fedj ◽  
Manel Wali ◽  
Abdelmajid Mahfoudh ◽  
Mahdi Ben Dhaou ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Surgical Management ◽  
Lung Abscess ◽  
Pulmonary Abscess

Lung abscess is uncommon in children. We report the case of a 6-month-old boy with pulmonary abscesses affecting more than one lobe with bronchial fistulas, which were refractory to medical treatment. We describe the surgical management and outcome.

The Canterbury technique for canalplasty via an endaural approach in the surgical management of chronic refractory otitis externa

2003 ◽  
Vol 117 (3) ◽  
pp. 195-197 ◽  
Author(s):  
H. R. Sharp ◽  
R. J. Oakley ◽  
N. D. Padgham
Keyword(s):  
Surgical Treatment ◽  
Soft Tissue ◽  
Medical Treatment ◽  
Surgical Management ◽  
Patient Group ◽  
Retrospective Review ◽  
Surgical Outcome ◽  
Otitis Externa ◽  
Patient Records

We describe an endaural technique for soft tissue and bony meatoplasty and canalplasty in the surgical management of chronic otitis externa unresponsive to medical treatment and out-patient microsuction. Following analysis of the surgical outcome via a retrospective review of patient records, we would recommend this surgical treatment in this patient group.

Tear cytokine profiling in patients with superior limbic keratoconjunctivitis who underwent medical treatment or in conjunction with surgical management

2019 ◽  
Vol 104 (5) ◽  
pp. 735-740
Author(s):  
Yi-Chen Sun ◽  
Yi-Hua Tang ◽  
Hau-Min Liou ◽  
Wei-Li Chen ◽  
Fung-Rong Hu
Keyword(s):  
Surgical Treatment ◽  
Medical Treatment ◽  
Surgical Management ◽  
Interferon Γ ◽  
Treatment Groups ◽  
Effective Treatment Modality ◽  
Cytokine Levels ◽  
Factor Α ◽  
Clinical Grading ◽  
Necrosis Factor

PurposeTo determine the correlation between superior limbic keratoconjunctivitis (SLK) and selected tear cytokines and to evaluate the efficacy of these cytokines in monitoring the response of patients with SLK to either medical treatment alone or in combination with conjunctival resection.DesignA cohort study.MethodsTwenty-five eyes of 13 patients with SLK were assigned to either medically responsive or surgical treatment groups depending on their responses 1 month after initial medical treatment. Treatment efficacy was assessed by improvements in clinical grading and decreases in the levels of tear cytokines.ResultsFourteen eyes were improved by medical treatment alone, whereas satisfactory outcomes were achieved for the remaining 11 eyes after surgical management. The overall grading prior to medical treatment was lower in medically responsive group compared with surgical treatment group (p=0.0139). Among the examined tear cytokines, monocyte chemoattractant protein (MCP)-1 was positively associated with the severity of clinical grading (p=0.0251). While both treatments significantly decreased the levels of MCP-1 and interleukin-6, surgical treatment also decreased the levels of interferon-γ and tumour necrosis factor-α. Notably, overall cytokine levels after surgical treatment were lower than those after medical treatment alone.ConclusionsSince an association of tear MCP-1 level with the clinical grading and treatment response of SLK was observed in this study, tear MCP-1 may be a potential indicator of SLK disease severity. According to the degree to which the tear cytokine levels were decreased, surgical treatment appears to be an effective treatment modality for patients with SLK who are refractory to medical treatment alone.

Chitin, a key factor in immune regulation: lesson from infection with fungi and chitin bearing parasites

2015 ◽  
Vol 60 (2) ◽  
Author(s):  
Klaudia Brodaczewska ◽  
Katarzyna Donskow-Łysoniewska ◽  
Maria Doligalska
Keyword(s):  
Immune Response ◽  
Medical Treatment ◽  
Immune Regulation ◽  
Parasitic Nematodes ◽  
Molecular Characteristics ◽  
Pathogenic Species ◽  
Natural Polymer ◽  
Key Factor ◽  
The Common

AbstractThe probability of infection with fungi, as well as parasitic nematodes or arthropods may increase in overcrowded population of animals and human. The widespread overuse of drugs and immunosuppressants for veterinary or medical treatment create an opportunity for many pathogenic species. The aim of the review is to present the common molecular characteristics of such pathogens as fungi and nematodes and other chitin bearing animals, which may both activate and downregulate the immune response of the host. Although these pathogens are evolutionary distinct and distant, they may provoke similar immune mechanisms. The role of chitin in these phenomena will be reviewed, highlighting the immune reactions that may be induced in mammals by this natural polymer.

scholarly journals Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

2013 ◽  
Vol 24 (2) ◽  
pp. 109-112 ◽  
Author(s):  
Genevieve Walls ◽  
Lisa Noonan ◽  
Elizabeth Wilson ◽  
David Holland ◽  
Simon Briggs
Keyword(s):  
Literature Review ◽  
Medical Treatment ◽  
Surgical Management ◽  
Swimming Pool ◽  
Polyhexamethylene Biguanide ◽  
The Common ◽  
Fungal Osteomyelitis ◽  
Immunocompetent Patients

Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.

Sinus Disease in the Immunocompromised Host

1992 ◽  
Vol 6 (3) ◽  
pp. 115-118 ◽  
Author(s):  
Darius Kohan ◽  
Jane-Marie G. Skorina ◽  
Joseph B. Jacobs ◽  
Arthur Lebowitz ◽  
Stephen G. Rothstein
Keyword(s):  
Staphylococcus Aureus ◽  
Medical Treatment ◽  
Surgical Management ◽  
Immunocompromised Host ◽  
Immunocompromised Patients ◽  
Aggressive Treatment ◽  
Sinus Disease ◽  
Intravenous Antibiotics ◽  
Complications Of Surgery ◽  
Fatal Illness

Sinusitis in the immunocompromised person can be a fulminant or even fatal illness. Aggressive treatment with intravenous antibiotics and surgery is often warranted. We report 13 cases of sinusitis in immunocompromised patients who, having failed medical treatment, required surgical management of their sinus disease. Among the patients whose sinuses were cultured intraoperatively, 63% grew Staphylococcus aureus. Most of the patients showed improvement in their infections, and none had complications of surgery.

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