Handgrip strength asymmetry is associated with future falls in older Americans

2020 ◽  
Author(s):  
Ryan McGrath ◽  
Brian C. Clark ◽  
Matteo Cesari ◽  
Carol Johnson ◽  
Donald A. Jurivich
Keyword(s):  
Handgrip Strength ◽  
Older Americans ◽  
Strength Asymmetry

scholarly journals Handgrip Strength Asymmetry Is Associated With Functional Disability In Older Americans

2021 ◽  
Vol 53 (8S) ◽  
pp. 221-221
Author(s):  
Ryan McGrath ◽  
Lukus Klawitter ◽  
Donald Jurivich ◽  
Brenda Vincent ◽  
Grant Tomkinson ◽  
...  
Keyword(s):  
Functional Disability ◽  
Handgrip Strength ◽  
Older Americans ◽  
Strength Asymmetry

scholarly journals Handgrip Strength Asymmetry and Weakness Are Differentially Associated with Functional Limitations in Older Americans

2020 ◽  
Vol 17 (9) ◽  
pp. 3231 ◽  
Author(s):  
Kyle Collins ◽  
Nathaniel Johnson ◽  
Lukus Klawitter ◽  
Roman Waldera ◽  
Sherri Stastny ◽  
...  
Keyword(s):  
Functional Disability ◽  
Handgrip Strength ◽  
Functional Limitations ◽  
Health Conditions ◽  
Older Americans ◽  
Health And Nutrition ◽  
Age Related ◽  
Strength Capacity ◽  
Strength Asymmetry ◽  
Nationally Representative

Background: Handgrip strength (HGS) is a convent measure of strength capacity and associated with several age-related health conditions such as functional disability. Asymmetric strength between limbs has been linked to diminished function. Therefore, both HGS asymmetry and weakness could be associated with functional disability. We examined the associations of HGS asymmetry and weakness on functional limitations in a nationally representative sample of older Americans. Methods: Data were analyzed from 2689 adults ≥ 60 years who participated in the 2011–2012 and 2013–2014 waves of the National Health and Nutrition Examination Survey. Weakness was defined as HGS < 26 kg for men and < 16 kg for women. Asymmetry was determined from the ratio of the dominant and non-dominant HGS. Those with HGS ratio 0.9–1.1 were considered as having HGS symmetry, and those outside this range had asymmetry. Results: Compared to those with symmetric HGS and were not weak, those with weakness alone, and both weakness and HGS asymmetry had 2.47 (95% confidence interval [CI]: 1.14–5.35) and 3.93 (CI: 1.18–13.07) greater odds for functional limitations, respectively. However, HGS asymmetry alone was not associated with functional limitations (odds ratio: 0.80; CI: 0.62–1.03). Conclusion: The use of HGS asymmetry in protocols could improve the prognostic value of handgrip dynamometers.

451 THE BEST MARKER FOR COGNITION—RELATIVE HANDGRIP STRENGTH, ASYMMETRY OR WEAKNESS?

2021 ◽  
Vol 50 (Supplement_2) ◽  
pp. ii5-ii7
Author(s):  
V Ho ◽  
C Chen ◽  
R A Merchant
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Handgrip Strength ◽  
Demographic Characteristics ◽  
Hand Dominance ◽  
Perceived Health Status ◽  
Cognitive Limitations ◽  
Strength Asymmetry ◽  
The Impact

Abstract Introduction Handgrip strength (HGS) is increasingly used to estimate overall muscle strength. Association between low HGS and cognitive decline has been well documented. Recently, McGrath’s team elucidated a new dimension of HGS asymmetry with important implications on physical and cognitive limitations. It is unclear if these effects can be generalised. The Asian working group for sarcopenia (AWGS) has called for ‘special considerations’ due to ‘anthropometric and cultural or lifestyle-related differences’6. Hence, we aim to investigate if HGS asymmetry is associated with cognition in Asians. Methodology We defined sarcopenia by AWGS consensus: HGS &lt;28 kg for men; &lt;18 kg for women. Asymmetry was HGS &gt;10% stronger on either hand; relative HGS was HGS adjusted for BMI. Low cognitive function was defined as MMSE&lt;26. We compared weakness alone, any HGS asymmetry or relative HGS alone and combination of weakness and HGS asymmetry or relative HGS asymmetry. Each model was adjusted for demographic characteristics, hand dominance, obesity, frailty, physical activity, depression and perceived health status. Results 738 Asian subjects participated. Mean age 70.8 ± 0.2 years, 45.1% males, 82.5% Chinese. More than 50% have multimorbidity. 5.4% were frail. Mean BMI 24.4 ± 0.1 kg/m2. Mean HGS 22.6 ± 0.3. 93 (12.7%) had symmetrical HGS and not weak, 59 (7.8%) asymmetrical and not weak, 321 (43.6%) symmetrical and weak, 265 (35.9%) asymmetrical and weak. Mean MMSE scores for weakness alone, asymmetry alone and combined weakness and asymmetry are 26.6 ± 0.1, 26.8 ± 0.2 and 26.5 ± 0.2 respectively. HGS asymmetry alone was not associated with better cognitive function OR 0.66 (95%CI: 0.30–1.44). Combined asymmetry and weakness was non-significantly linked to worse cognition OR 2.14 (95%CI: 0.79–5.82). We found relative HGS to be protective for cognitive decline, OR 0.31 (95%CI: 0.12–0.78, p = 0.012). Conclusion Our study highlights the impact of ethnicity in sarcopenia research. Our population shows association of relative HGS with cognition. Further longitudinal studies are needed.

scholarly journals MUSCLE WEAKNESS IS ASSOCIATED WITH DISABILITY AND CHRONIC MULTIMORBIDITY IN MIDDLE-AGED AND OLDER AMERICANS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S316-S316
Author(s):  
Mark Peterson ◽  
Jessica Faul
Keyword(s):  
Grip Strength ◽  
Handgrip Strength ◽  
Healthcare Providers ◽  
High Sensitivity ◽  
Inverse Association ◽  
Older Americans ◽  
Men And Women ◽  
Reactive Protein ◽  
Nationally Representative ◽  
Hs Crp

Abstract Background: The objective of this study was to use nationally-representative data on Americans age 50+ to determine the association between grip strength and inflammation as independent predictors of incident disability, chronic multimorbidity and dementia. Methods: Older adults (n=12,618) from the 2006-2008 waves of the Health and Retirement Study with 8-years of follow-up were included. Longitudinal modeling was performed to examine the association between baseline grip strength (normalized to body mass: NGS) and high sensitivity c-reactive protein (hs-CRP) (≥3.0 mg/L) with incident physical disabilities (i.e., ≥2 limitations to activities of daily living), chronic multimorbidity (≥2 of chronic conditions), and dementia. Results: The odds of incident disability were 1.28 (95% CI: 1.19-1.37) and 1.27 (95% CI: 1.21-1.36) for men and women respectively, for each 0.05-unit lower NGS. The odds of incident chronic multimorbidity were 1.22 (95% CI: 1.06-1.18) and 1.12 (95% CI: 1.06-1.17) for men and women respectively for each 0.05-unit lower NGS. The odds of incident dementia were 1.10 for men (95% CI: 1.02-1.20) for each 0.05-unit lower NGS, but there was no significant effect for women. Elevated hs-CRP was only associated with chronic multimorbidity among women (OR=1.60; 95%CI: 1.26-2.02). Conclusions: Our findings indicate a robust inverse association between NGS and disability and chronic, multimorbidity in older men and women, and dementia in men. Elevated hs-CRP was only associated with chronic multimorbidity among women. Healthcare providers should implement measures of handgrip strength in routine health assessments and discuss the potential dangers of weakness and interventions to improve strength with their patients.

Handgrip Strength Asymmetry and Weakness May Accelerate Time to Mortality in Aging Americans

2020 ◽  
Vol 21 (12) ◽  
pp. 2003-2007.e1 ◽  
Author(s):  
Ryan McGrath ◽  
Grant R. Tomkinson ◽  
Dain P. LaRoche ◽  
Brenda M. Vincent ◽  
Colin W. Bond ◽  
...  
Keyword(s):  
Handgrip Strength ◽  
Strength Asymmetry

Handgrip Strength Asymmetry and Weakness Are Associated With Future Morbidity Accumulation in Americans

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Lukus Klawitter ◽  
Brenda M. Vincent ◽  
Bong-Jin Choi ◽  
Joseph Smith ◽  
Kimberly D. Hammer ◽  
...  
Keyword(s):  
Handgrip Strength ◽  
Strength Asymmetry

scholarly journals Risk Factors for Smell Impairment and Alteration in Older Americans: NHANES 2013–2014 (P01-024-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Mary Camire ◽  
Emily Durán-Frontera ◽  
Mona Therrien
Keyword(s):  
Grip Strength ◽  
Body Mass ◽  
Handgrip Strength ◽  
Demographic Data ◽  
Hand Grip Strength ◽  
Older Americans ◽  
Funding Sources ◽  
Hand Grip ◽  
Age Related ◽  
Simple Logistic

Abstract Objectives This study examined relationships among smell impairment and health in adults over the age of 60 years. We hypothesized that persons with impaired or altered olfaction would be weaker (as shown by hand grip strength tests) and have a lower body mass index (BMI) ratios because they ate less. Methods The 2013–2014 NHANES database was use examined for smell identification scores, general demographic data, handgrip strength, and other types of data. Only persons aged 60 or older who had completed the Mobile Exam Center interview, and the complete smell and grip tests were included (n = 1287). Data were weighted to represent the U.S. population. Smell impairment was defined as five or fewer correct answers in the Odor Identification Test. Data-dependent statistical analyses (t-test, Wilcoxon rank sum, χ2) were performed to find differences based on specific criteria. Odds ratios (OR) with 95% confidence intervals were generated by simple logistic regression, and then a multivariable predictive model was developed. Results The NHANES participants included for these analyses were mainly non-Hispanic white (52.7%), college-educated (54.5%), and lived with someone (60%). The prevalence of smell impairment was 21.7% among persons aged 60 or older, but the prevalence rose to 44.8% among persons aged 75–80. The prevalence of self-reported smell alteration was 16.2%. Smell impairment was significantly associated with age 75–80 years (OR: 3.51, CI: 2.51–3.11), and an educational level of high school or less (OR: 1.70, CI: 1.40–2.30). After adjustment for gender, age, education, and race, smell impairment was associated with poor health self-ratings (OR: 2.63, CI: 1.30–5.40), more sedentary hours each day (OR: 1.07, CI: 1.03–1.11), and presence of smell alteration (OR: 3.00, CI: 2.10–4.60). Persons with normal muscle and hand grip strength were less likely to have a smell impairment or alteration. Conclusions Men aged 75–80 years were more at risk for smell impairment. Further research is needed to determine whether preservation of olfaction can forestall age-related reductions in appetite, and subsequent loss in body mass, particularly muscle. The inclusion of persons older than 80 years in the NHANES sampling would provide useful data for researchers. Funding Sources USDA Hatch funds.

Handgrip Strength Asymmetry and Weakness Together Are Associated With Functional Disability in Aging Americans

2020 ◽  
Author(s):  
Ryan McGrath ◽  
Brenda M Vincent ◽  
Donald A Jurivich ◽  
Kyle J Hackney ◽  
Grant R Tomkinson ◽  
...  
Keyword(s):  
Generalized Estimating Equations ◽  
Daily Living ◽  
Functional Disability ◽  
Handgrip Strength ◽  
National Sample ◽  
Dominant Hand ◽  
Predictive Utility ◽  
Strength Asymmetry ◽  
Adl Disability ◽  
Retirement Study

Abstract Background Evaluating handgrip strength (HGS) asymmetry may help to improve the prognostic value of HGS. This study sought to determine the associations of HGS asymmetry and weakness on future activities of daily living (ADL) disability in a national sample of aging Americans. Methods The analytic sample included 18,468 Americans aged ≥50 years from the 2006–2016 waves of the Health and Retirement Study. A handgrip dynamometer measured HGS. Those with HGS &gt;10% stronger on either hand were considered as having any HGS asymmetry. Individuals with HGS &gt;10% stronger on their dominant hand were considered as having dominant HGS asymmetry, while those with HGS &gt;10% stronger on their nondominant hand were classified as having nondominant HGS asymmetry. Men with HGS &lt;26 kg and women with HGS &lt;16 kg were considered weak. ADLs were self-reported. Generalized estimating equations were used for analyses. Results Relative to those with symmetric HGS and no weakness, each HGS asymmetry and weakness group had increased odds for future ADL disability: 1.11 (95% confidence interval [CI]: 1.02–1.20) for any HGS asymmetry alone, 1.42 (CI: 1.16–1.74) for weakness alone, and 1.81 (CI: 1.52–2.16) for both any HGS asymmetry and weakness. Most weakness and HGS asymmetry dominance groups had increased odds for future ADL disability: 1.30 (CI: 1.13–1.50) for nondominant HGS asymmetry alone, 1.42 (CI: 1.16–1.74) for weakness alone, 1.72 (CI: 1.29–2.29) for both weakness and nondominant HGS asymmetry, and 1.86 (CI: 1.52–2.28) for both weakness and dominant HGS asymmetry. Conclusions HGS asymmetry and weakness together may increase the predictive utility of handgrip dynamometers.

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