scholarly journals Handgrip Strength Asymmetry and Weakness Are Differentially Associated with Functional Limitations in Older Americans

Author(s):  
Kyle Collins ◽  
Nathaniel Johnson ◽  
Lukus Klawitter ◽  
Roman Waldera ◽  
Sherri Stastny ◽  
...  

Background: Handgrip strength (HGS) is a convent measure of strength capacity and associated with several age-related health conditions such as functional disability. Asymmetric strength between limbs has been linked to diminished function. Therefore, both HGS asymmetry and weakness could be associated with functional disability. We examined the associations of HGS asymmetry and weakness on functional limitations in a nationally representative sample of older Americans. Methods: Data were analyzed from 2689 adults ≥ 60 years who participated in the 2011–2012 and 2013–2014 waves of the National Health and Nutrition Examination Survey. Weakness was defined as HGS < 26 kg for men and < 16 kg for women. Asymmetry was determined from the ratio of the dominant and non-dominant HGS. Those with HGS ratio 0.9–1.1 were considered as having HGS symmetry, and those outside this range had asymmetry. Results: Compared to those with symmetric HGS and were not weak, those with weakness alone, and both weakness and HGS asymmetry had 2.47 (95% confidence interval [CI]: 1.14–5.35) and 3.93 (CI: 1.18–13.07) greater odds for functional limitations, respectively. However, HGS asymmetry alone was not associated with functional limitations (odds ratio: 0.80; CI: 0.62–1.03). Conclusion: The use of HGS asymmetry in protocols could improve the prognostic value of handgrip dynamometers.

2021 ◽  
Vol 53 (8S) ◽  
pp. 221-221
Author(s):  
Ryan McGrath ◽  
Lukus Klawitter ◽  
Donald Jurivich ◽  
Brenda Vincent ◽  
Grant Tomkinson ◽  
...  

2020 ◽  
Vol 49 (4) ◽  
pp. 634-639 ◽  
Author(s):  
G R Tomkinson ◽  
T Kidokoro ◽  
T Dufner ◽  
S Noi ◽  
J S Fitzgerald ◽  
...  

Abstract Objective to estimate temporal trends in handgrip strength (HGS) for older Japanese adults between 1998 and 2017. Design and methods adults aged 60–79 years were included. Annual nationally representative HGS data (n = 176,449) for the 19-year study period were obtained from the Japanese Ministry of Education, Culture, Sports, Science and Technology. Temporal trends in mean HGS were estimated by sample-weighted regression models relating the year of testing to mean HGS. National trends in absolute, percent and standardised HGS were estimated by a post-stratified population-weighting procedure. Temporal trends in variability were estimated as the ratio of coefficients of variation (CVs). Results collectively, there was a small improvement in mean HGS of 1.4 kg (95% confidence interval [CI]: 1.3–1.5), 4.5% (95%CI: 4.3–4.7) or 0.27 standard deviations (95%CI: 0.26–0.28) between 1998 and 2017. The rate of improvement progressively increased over time, with more recent values (post-2008) 1.5-fold larger than earlier values. Gender- and age-related temporal differences were negligible. Variability in HGS declined substantially over time (ratio of CVs [95%CI]: 0.88 [0.86–0.90]), with declines 1.9-fold larger in women compared to men and 1.7-fold larger in 70- to 79-year-olds compared to 60- to 69-year-olds. Conclusions there has been a small, progressive improvement in mean HGS for older Japanese adults since 1998, which is suggestive of a corresponding improvement in strength capacity. The substantial decline in variability indicates that the improvement in mean HGS was not uniform across the population.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S316-S316
Author(s):  
Mark Peterson ◽  
Jessica Faul

Abstract Background: The objective of this study was to use nationally-representative data on Americans age 50+ to determine the association between grip strength and inflammation as independent predictors of incident disability, chronic multimorbidity and dementia. Methods: Older adults (n=12,618) from the 2006-2008 waves of the Health and Retirement Study with 8-years of follow-up were included. Longitudinal modeling was performed to examine the association between baseline grip strength (normalized to body mass: NGS) and high sensitivity c-reactive protein (hs-CRP) (≥3.0 mg/L) with incident physical disabilities (i.e., ≥2 limitations to activities of daily living), chronic multimorbidity (≥2 of chronic conditions), and dementia. Results: The odds of incident disability were 1.28 (95% CI: 1.19-1.37) and 1.27 (95% CI: 1.21-1.36) for men and women respectively, for each 0.05-unit lower NGS. The odds of incident chronic multimorbidity were 1.22 (95% CI: 1.06-1.18) and 1.12 (95% CI: 1.06-1.17) for men and women respectively for each 0.05-unit lower NGS. The odds of incident dementia were 1.10 for men (95% CI: 1.02-1.20) for each 0.05-unit lower NGS, but there was no significant effect for women. Elevated hs-CRP was only associated with chronic multimorbidity among women (OR=1.60; 95%CI: 1.26-2.02). Conclusions: Our findings indicate a robust inverse association between NGS and disability and chronic, multimorbidity in older men and women, and dementia in men. Elevated hs-CRP was only associated with chronic multimorbidity among women. Healthcare providers should implement measures of handgrip strength in routine health assessments and discuss the potential dangers of weakness and interventions to improve strength with their patients.


2019 ◽  
pp. bjophthalmol-2019-314853
Author(s):  
Zhuoting Zhu ◽  
Huan Liao ◽  
Wei Wang ◽  
Jane Scheetz ◽  
Jian Zhang ◽  
...  

PurposeTo investigate the association between age-related macular degeneration (AMD) and subjective cognitive complaints (SCCs) in the USA.MethodsA total of 5604 participants aged 40 years and older from the 2005–2008 National Health and Nutrition Examination Survey were included. Retinal photography was graded into no AMD, early and late AMD based on the modification of the Wisconsin Age-Related Maculopathy Grading System. SCCs were based on the self-reported difficulty in remembering or confusion. Sample weights were used to generate nationally representative data. Multivariate regression analyses were used to assess the association between AMD severity and SCCs, controlling for potential confounders.ResultsParticipants with any AMD had higher prevalence of SCCs relative to participants without AMD (6.8% vs 13.6%, p<0.001). After adjusting for potential confounding factors, presence of any AMD was significantly associated with 1.62-fold higher odds of having SCCs (95% CI 1.16 to 2.27, p=0.007). Similarly, participants with early (OR 1.58; 95% CI 1.14 to 2.17, p=0.007) and late AMD (OR 2.02; 95% CI 1.08 to 3.79, p=0.030) were also associated with elevated odds of reporting SCCs after controlling for confounders.ConclusionsWe found significant associations between AMD severity and SCCs in this US population. More attention should be paid on the subjective memory function and potential risk of cognitive decline among patients with AMD.


2019 ◽  
Vol 32 (9) ◽  
pp. 1075-1083 ◽  
Author(s):  
Ryan McGrath ◽  
Sherri Stastny ◽  
Shanon Casperson ◽  
Lisa Jahns ◽  
James Roemmich ◽  
...  

Objective: We sought to determine whether daily protein intake and protein distribution across eating occasions were associated with functional disability in a national sample of older Americans. Methods: Data from 8,070 adults aged ≥60 years from the 2007-2016 waves of the National Health and Nutrition Examination Survey were included. Protein intake and functional capacity was self-reported. A daily protein recommendation of ≥1.0 g/kg/day was utilized. The daily protein recommendation was then spread-out across four meals, whereby a ≥0.25 g/kg/meal threshold was used. Results: Those meeting the daily protein recommendation had 0.78 (95% confidence interval [CI] = [0.65, 0.93]) decreased odds for functional disability. Persons meeting the protein intake threshold per eating occasion for one, two, three, and four occasions had 0.60 (CI = [0.38, 0.95]), 0.48 (CI = [0.30, 0.77]), 0.47 (CI = [0.29, 0.77]), and 0.39 (CI = [0.20, 0.75]) decreased odds for functional disability, respectively. Discussion: Protein consumption seems to be important for preserving function in older Americans.


2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Thomas O Obisesan ◽  
Muktar H Aliyu ◽  
Vernon Bond ◽  
Richard G Adams ◽  
Abimbola Akomolafe ◽  
...  

Author(s):  
Ryan McGrath ◽  
Brian C. Clark ◽  
Matteo Cesari ◽  
Carol Johnson ◽  
Donald A. Jurivich

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Mary Camire ◽  
Emily Durán-Frontera ◽  
Mona Therrien

Abstract Objectives This study examined relationships among smell impairment and health in adults over the age of 60 years. We hypothesized that persons with impaired or altered olfaction would be weaker (as shown by hand grip strength tests) and have a lower body mass index (BMI) ratios because they ate less. Methods The 2013–2014 NHANES database was use examined for smell identification scores, general demographic data, handgrip strength, and other types of data. Only persons aged 60 or older who had completed the Mobile Exam Center interview, and the complete smell and grip tests were included (n = 1287). Data were weighted to represent the U.S. population. Smell impairment was defined as five or fewer correct answers in the Odor Identification Test. Data-dependent statistical analyses (t-test, Wilcoxon rank sum, χ2) were performed to find differences based on specific criteria. Odds ratios (OR) with 95% confidence intervals were generated by simple logistic regression, and then a multivariable predictive model was developed. Results The NHANES participants included for these analyses were mainly non-Hispanic white (52.7%), college-educated (54.5%), and lived with someone (60%). The prevalence of smell impairment was 21.7% among persons aged 60 or older, but the prevalence rose to 44.8% among persons aged 75–80. The prevalence of self-reported smell alteration was 16.2%. Smell impairment was significantly associated with age 75–80 years (OR: 3.51, CI: 2.51–3.11), and an educational level of high school or less (OR: 1.70, CI: 1.40–2.30). After adjustment for gender, age, education, and race, smell impairment was associated with poor health self-ratings (OR: 2.63, CI: 1.30–5.40), more sedentary hours each day (OR: 1.07, CI: 1.03–1.11), and presence of smell alteration (OR: 3.00, CI: 2.10–4.60). Persons with normal muscle and hand grip strength were less likely to have a smell impairment or alteration. Conclusions Men aged 75–80 years were more at risk for smell impairment. Further research is needed to determine whether preservation of olfaction can forestall age-related reductions in appetite, and subsequent loss in body mass, particularly muscle. The inclusion of persons older than 80 years in the NHANES sampling would provide useful data for researchers. Funding Sources USDA Hatch funds.


2016 ◽  
Vol 29 (1) ◽  
pp. 128-148 ◽  
Author(s):  
Caitlin E. Coyle ◽  
Bernard A. Steinman ◽  
Jie Chen

Objectives: This study examined the associations of two measures of vision impairment (i.e., a clinical measure of visual acuity and self-reported vision status) and social isolation in a nationally representative sample of Americans aged 60 and older. Method: Five cycles of the National Health and Nutrition Examination Survey (NHANES IV; 1999-2008) were used to estimate successive logistic regression models, holding constant demographic characteristics, chronic illness, functional limitations, and disability. Results: Effects of both measures of vision impairment in predicting social isolation were substantially reduced or eliminated in adjusted models. Where significant effects of vision impairment on social isolation remained, a strong effect was found for self-reported poor vision (odds ratio = 1.53; 95% confidence interval = [1.08, 2.16]). Discussion: As one of the better vision-related predictors of social isolation, self-reported vision is among the easiest and inexpensive to assess. The use of self-reported vision as a screening criterion for social isolation is discussed.


2020 ◽  
Vol 8 ◽  
pp. 205031212091035 ◽  
Author(s):  
Ryan McGrath ◽  
Nathaniel Johnson ◽  
Lukus Klawitter ◽  
Sean Mahoney ◽  
Kara Trautman ◽  
...  

Measures of handgrip strength can be used to conveniently assess overall muscle strength capacity. Although stand-alone measures of handgrip strength provide robust health information, the clinical meaningfulness to determine prevention and treatment options for weakness remains limited because the etiology of muscle weakness remains unclear. Moreover, clinical outcomes associated with handgrip strength are wide-ranging. Therefore, disentangling how handgrip strength is associated with health conditions that are metabolically or neurologically driven may improve our understanding of the factors linked to handgrip strength. The purpose of this topical review was to highlight and summarize evidence examining the associations of handgrip strength with certain health outcomes that are metabolically and neurologically driven. From this perusal of the literature, we posit that stand-alone handgrip strength be considered an umbrella assessment of the body systems that contribute to strength capacity, and a panoptic measurement of muscle strength that is representative of overall health status, not a specific health condition. Recommendations for future strength capacity–related research are also provided.


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