Dissolution behaviour and imageability of ternary borate glasses for use in geniculate artery embolization

AbstractSixteen borate glass compositions comprising K2O and SrO were screened, using a design of mixtures approach, to model compositional effects on dissolution, CT imageability, and MRI relaxivity (R2). Based on the characteristics of each network, together with dose determination and toxicological risk, the composition identified as BKSA16 was selected as a preferred composition for pre-clinical evaluations related to geniculate artery embolization (GAE). Accordingly, BKSA16 particles were subjected to a flame spheroidization process and recharacterized, including the evaluation of residual mass at 72 h in physiologically representative media along with clinical determinations of suspension time (ease of use). For both the irregular particles and microspheres residual mass was present at 72 h in physiologically representative media. Additionally, both the microspheres and irregular particles achieved suspension times deemed to be acceptable for clinical use. The collective data confirms that BKSA16 microspheres have a range of beneficial features (specifically both degradable and imageable) suited to GAE.

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Treatment time, ease of use and cost associated with use of Equashield™, PhaSeal®, or no closed system transfer device for administration of cancer chemotherapy to a dog model

Veterinary and Comparative Oncology ◽

10.1111/vco.12148 ◽

2015 ◽

Vol 15 (1) ◽

pp. 163-173 ◽

Cited By ~ 7

Author(s):

K. Kicenuik ◽

N. Northrup ◽

A. Dawson ◽

J. Locke ◽

J. A. Villamil ◽

...

Keyword(s):

Cancer Chemotherapy ◽

Closed System ◽

Treatment Time ◽

Ease Of Use ◽

Dog Model ◽

Time Ease ◽

Transfer Device

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Statistical approach to study of lithium magnesium metaborate glasses

Open Chemistry ◽

10.1515/chem-2017-0008 ◽

2017 ◽

Vol 15 (1) ◽

pp. 61-66 ◽

Cited By ~ 1

Author(s):

Miroslava Nedyalkova ◽

Hristo Hristov ◽

Vasil Simeonov

Keyword(s):

Borate Glass ◽

Hierarchical Cluster ◽

Structural Data ◽

Structural Features ◽

Borate Glasses ◽

Data Set ◽

Alkali Borate Glasses ◽

Instrumental Methods ◽

Glass Compositions ◽

Glass Properties

AbstractAlkali borate glasses and alkaline earth borate glasses are commonly used materials in the field of optoelectronics. Infrared (FTIR) and Raman spectroscopy are valuable tools for structural investigation of borate glass networks. The compositional and structural variety of lithium magnesium metaborate glasses is usually determined by traditional instrumental methods. In this study a data set is classified by structural and physicochemical parameters (FTIR, Raman spectra, glass transition temperature-Tg). Characterisation of magnesium containing metaborate glasses by multivariate statistics (hierarchical cluster analysis) to reveal potential relationships (similarity or dissimilarity) between the type of glasses included in the data set using specific structural features available in the literature is conducted. The clustering of the glass objects indicates a good separation of different magnesium containing borate glass compositions. The grouping of variables concerning Tg and structural data for BO3 and BO4 linkage confirms that BO4/BO3 ratios strongly affect Tg. Additionally, patterns of similarity could be detected not only between the glass composition but also between the features (variables) describing the glasses. The proposed approach can be further used as an expert tool for glass properties prediction or fingerprinting (identification of unknown compositions).

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A Comparison of Methods of Controlling the Movement of an Exoskeleton, Supporting Movements of the Upper Limb Using Signals of Muscle Activity and Manual Controls

Problems of Mechatronics Armament Aviation Safety Engineering ◽

10.5604/01.3001.0014.3705 ◽

2020 ◽

Vol 11 (3) ◽

pp. 19-32

Author(s):

Jarosław JANKOWSKI ◽

Patrycja ŁACH

Keyword(s):

Upper Limb ◽

Muscle Activity ◽

Execution Time ◽

Ease Of Use ◽

Manual Control ◽

Comparison Of Methods ◽

Task Execution ◽

Task Execution Time ◽

Control Devices ◽

Time Ease

The paper presents the research methodology and the analysis of the results of the comparison test of two methods of controlling the exoskeleton of the upper limb using signals of muscle activity and manual control devices. The results show the advantage of the joystick method over EMG in terms of usability, task execution time, ease of use and comfort.

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Development of a GeoGebra-Assisted Calculus Worksheet to Enhance Students’ Understanding

International Journal of Information and Education Technology ◽

10.18178/ijiet.2021.11.10.1550 ◽

2021 ◽

Vol 11 (10) ◽

pp. 456-463

Author(s):

Yerizon ◽

◽

Siti Fatimah ◽

Fridgo Tasman

Keyword(s):

Preliminary Analysis ◽

Mathematical Understanding ◽

Ease Of Use ◽

Development Model ◽

Prototype Development ◽

Alternative Method ◽

Implementation Time ◽

Potential Impact ◽

The Given ◽

Time Ease

The goal of this study is to develop a GeoGebra-assisted worksheet to enhance students' understanding of calculus. Many studies report that students have difficulty understanding calculus. GeoGebra provides an alternative method to overcome the difficulties associated with calculus. The Plomp development model consists of three phases: specifically, preliminary analysis, prototype development and an assessment was used in this study. The subjects of this study were 37 students. The results of this study are valid in terms of content, presentation, linguistics and graphics and practical in terms of implementation, time, ease of use and effective in terms of its potential impact on students' mathematical understanding. The GeoGebra-assisted worksheet can help students rediscover the given concept, while the use of visualization of the calculus concept can significantly enhance students’ mathematical understanding. Likewise, GeoGebra-assisted worksheets can be used to enhance students’ understanding of calculus. Teachers are suggested using GeoGebra in order to build students’ understanding on calculus subject.

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Morphogenetic machines revealed: Microscopy of living cells in the embryo of the frog, Xenopus laevis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100146709 ◽

1993 ◽

Vol 51 ◽

pp. 172-173

Author(s):

Ray Keller

Keyword(s):

Image Processing ◽

Fluorescent Dyes ◽

Cell Movement ◽

Living Cells ◽

Ease Of Use ◽

Low Light ◽

Amphibian Embryo ◽

Large Populations ◽

Light Fluorescence ◽

Video Image Processing

The amphibian embryo offers advantages of size, availability, and ease of use with both microsurgical and molecular methods in the analysis of fundamental developmental and cell biological problems. However, conventional wisdom holds that the opacity of this embryo limits the use of methods in optical microscopy to resolve the cell motility underlying the major shape-generating processes in early development.These difficulties have been circumvented by refining and adapting several methods. First, methods of explanting and culturing tissues were developed that expose the deep, nonepithelial cells, as well as the superficial epithelial cells, to the view of the microscope. Second, low angle epi-illumination with video image processing and recording was used to follow patterns of cell movement in large populations of cells. Lastly, cells were labeled with vital, fluorescent dyes, and their behavior recorded, using low-light, fluorescence microscopy and image processing. Using these methods, the details of the cellular protrusive activity that drives the powerful convergence (narrowing)

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