Fatty acid metabolism in Paramecium Oleic acid metabolism and inhibition of polyunsaturated fatty acid synthesis by triparanol

Author(s):  
Dennis E. Rhoads ◽  
Edna S. Kaneshiro
2020 ◽  
Vol 11 (10) ◽  
pp. 8625-8636
Author(s):  
Zhi Chen ◽  
Shuangfeng Chu ◽  
Yusheng Liang ◽  
Tianle Xu ◽  
Yujia Sun ◽  
...  

Both mRNA and miRNA play an important role in the regulation of mammary fatty acid metabolism and milk fat synthesis.


Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3296 ◽  
Author(s):  
Tai-Mei Di ◽  
Shao-Lan Yang ◽  
Feng-Yu Du ◽  
Lei Zhao ◽  
Xiao-Han Li ◽  
...  

A new triterpenoid saponin, named oleiferasaponin A2, was isolated and identified from Camellia oleifera defatted seeds. Oleiferasaponin A2 exhibited anti-hyperlipidemic activity on HepG2 cell lines. Further study of the hypolipidemic mechanism showed that oleiferasaponin A2 inhibited fatty acid synthesis by significantly down-regulating the expression of SREBP-1c, FAS and FAS protein, while dramatically promoting fatty acid β-oxidation by up-regulating the expression of ACOX-1, CPT-1 and ACOX-1 protein. Our results demonstrate that the oleiferasaponin A2 possesses potential medicinal value for hyperlipidemia treatment.


2014 ◽  
Vol 7 (1) ◽  
pp. 172-183 ◽  
Author(s):  
Catherine H. Le ◽  
Christopher M. Mulligan ◽  
Melissa A. Routh ◽  
Gerrit J. Bouma ◽  
Melinda A. Frye ◽  
...  

2013 ◽  
Vol 50 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Pauline Beguin ◽  
Anne-Catherine Schneider ◽  
Eric Mignolet ◽  
Yves-Jacques Schneider ◽  
Yvan Larondelle

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