Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21

1995 ◽  
Vol 674 (2) ◽  
pp. 252-259 ◽  
Author(s):  
Gary W. Arendash ◽  
Gregory J. Sengstock ◽  
Paul R. Sanberg ◽  
William R. Kem
Keyword(s):  
Learning And Memory ◽  
Nicotinic Receptor ◽  
Receptor Agonist ◽  
Chronic Administration ◽  
Aged Rats ◽  
Improved Learning

A dopamine D1 receptor agonist improved learning and memory in morphine-treated rats

2018 ◽  
Vol 40 (12) ◽  
pp. 1080-1087 ◽  
Author(s):  
Qiaofeng Liu ◽  
Yanxia Li ◽  
Yang Liu ◽  
Yanshuang Zhao ◽  
Xuemei Li ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Receptor Agonist ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Improved Learning

scholarly journals Effect of chronic administration of arachidonic acid on the performance of learning and memory in aged rats

2019 ◽  
Vol 63 (0) ◽  
Author(s):  
Takayuki Inoue ◽  
Michio Hashimoto ◽  
Masanori Katakura ◽  
Shahdat Hossain ◽  
Kentaro Matsuzaki ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Learning And Memory ◽  
Chronic Administration ◽  
Aged Rats

Effects of lobeline, a nicotinic receptor agonist, on learning and memory

1993 ◽  
Vol 45 (3) ◽  
pp. 571-576 ◽  
Author(s):  
Michael W. Decker ◽  
Mark J. Majchrzak ◽  
Stephen P. Arnerić
Keyword(s):  
Learning And Memory ◽  
Nicotinic Receptor ◽  
Receptor Agonist

Chronic administration of the histamine H3 receptor agonist immepip decreases l-Dopa-induced dyskinesias in 6-hydroxydopamine-lesioned rats

2019 ◽  
Vol 236 (6) ◽  
pp. 1937-1948 ◽  
Author(s):  
Alberto Avila-Luna ◽  
Camilo Ríos ◽  
Arturo Gálvez-Rosas ◽  
Sergio Montes ◽  
José-Antonio Arias-Montaño ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
Chronic Administration ◽  
Histamine H3 Receptor ◽  
H3 Receptor ◽  
6 Hydroxydopamine ◽  
Histamine H3

scholarly journals Tocotrienol improves learning and memory deficit of aged rats

2016 ◽  
Vol 58 (2) ◽  
pp. 114-121 ◽  
Author(s):  
Nozomi Kaneai ◽  
Kazumi Sumitani ◽  
Koji Fukui ◽  
Taisuke Koike ◽  
Hirokatsu Takatsu ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Memory Deficit ◽  
Aged Rats ◽  
Learning And Memory Deficit

Cytyzyna w terapii zaprzestania palenia tytoniu

2020 ◽  
Vol 23 (2) ◽  
Author(s):  
Patrycjusz Kołodziejczyk ◽  
Katarzyna Baranowska-Kempisty ◽  
Piotr Bernat ◽  
Piotr Tutka
Keyword(s):  
Smoking Cessation ◽  
Adverse Events ◽  
Nicotinic Receptor ◽  
Receptor Agonist ◽  
Addiction Treatment ◽  
Causes Of Death ◽  
Low Frequency ◽  
Duration Of Treatment ◽  
Over The Counter ◽  
Natural Plant

Tobacco smoking is one of the leading causes of death among people. Cytisine, a plant alkaloid considered to be the oldest medication for smoking cessation, has been used in Poland since the 1970s. The drug is a partial nicotinic receptor agonist, with pharmacological actions close to those of nicotine and varenicline (a synthetic cytisine derivative and most expensive smoking cessation medication currently available). Cytisine has several advantages compared to existing smoking cessation drugs, including: 1) it is more effective than placebo and nicotine replacement therapy, and at least as effective as varenicline, 2) its use is associated with a low frequency of adverse events, 3) it is available as over the counter medicine and is much cheaper than other smoking cessation drugs that are cost-prohibitive, 4) it derives from a natural plant and may be preferred by smokers who do not want to use other treatments, 5) it has shorter duration of treatment (i.e. 25 days) compared to other medicines for smoking cessation. This review describes the use of cytisine for nicotine addiction treatment, mechanism of anti-smoking action, pharmacokinetics, efficacy, tolerability and safety.

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