Serum levels of proline imino-peptidase in normal adults and children

1977 ◽  
Vol 81 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Hiroshi Nakano ◽  
Shuhei Nomoto ◽  
Saburo Ohnishi ◽  
Kenichi Ito
Keyword(s):  
Serum Levels ◽  
Adults And Children ◽  
Normal Adults

MUCOLYTIC ENZYME SYSTEMS

PEDIATRICS ◽  
1953 ◽  
Vol 12 (5) ◽  
pp. 575-583
Author(s):  
ROBERT A. GOOD ◽  
VINCENT C. KELLEY ◽  
THOMAS A. GOOD ◽  
DAVID GLICK
Keyword(s):  
Newborn Infant ◽  
Serum Levels ◽  
Maternal Serum ◽  
First Year ◽  
Enzyme Systems ◽  
Hyaluronidase Inhibitor ◽  
Normal Adults

Normal maternal serum and newborn infant serum have been compared with respect to their content of nonspecific hyaluronidase inhibitor and mucoprotein. Elevations in serum levels of hyaluronidase inhibitor and mucoprotein were found in maternal serum while decreased concentrations of mucoprotein and normal levels of hyaluronidase inhibitor characterized the serum of infants at birth. Mucoprotein concentrations in maternal serum increase for a period following delivery and remain at high levels for at least one month. Increase from low mucoprotein levels occurred in infants' serums during the first month of life and levels comparable to those of normal adults were found throughout the remainder of the first year. The relation of these findings to studies of other protein constituents in maternal and infant serum is discussed as are possible mechanisms to explain the results obtained.

scholarly journals Proteomic Analysis of Sera from Common Variable Immunodeficiency Patients Undergoing Replacement Intravenous Immunoglobulin Therapy

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Giuseppe Spadaro ◽  
Concetta D'Orio ◽  
Arturo Genovese ◽  
Antonella Galeotafiore ◽  
Chiara D'Ambrosio ◽  
...  
Keyword(s):  
Common Variable Immunodeficiency ◽  
Serum Proteins ◽  
Immunoglobulin Therapy ◽  
Normal Subjects ◽  
Serum Levels ◽  
Serum Samples ◽  
Intravenous Immunoglobulin Therapy ◽  
Proteomic Approach ◽  
Adults And Children ◽  
Common Variable

Common variable immunodeficiency is the most common form of symptomatic primary antibody failure in adults and children. Replacement immunoglobulin is the standard treatment of these patients. By using a differential proteomic approach based on 2D-DIGE, we examined serum samples from normal donors and from matched, naive, and immunoglobulin-treated patients. The results highlighted regulated expression of serum proteins in naive patients. Among the identified proteins, clusterin/ApoJ serum levels were lower in naive patients, compared to normal subjects. This finding was validated in a wider collection of samples from newly enrolled patients. The establishment of a cellular system, based on a human hepatocyte cell line HuH7, allowed to ascertain a potential role in the regulation ofCLUgene expression by immunoglobulins.

Microbiology of the middle meatus: a comparison between normal adults and children

2000 ◽  
Vol 114 (3) ◽  
pp. 184-188 ◽  
Author(s):  
Frans Gordts ◽  
Stijn Halewyck ◽  
Denis Pierard ◽  
Peter A. R. Clement ◽  
Leonard Kaufman
Keyword(s):  
Streptococcus Pneumoniae ◽  
Moraxella Catarrhalis ◽  
Healthy Adults ◽  
Middle Meatus ◽  
Coagulase Negative Staphylococci ◽  
Predominant Species ◽  
Commensal Flora ◽  
Adults And Children ◽  
Normal Adults ◽  
Staphyloccus Aureus

Middle meatal samples were obtained from 52 carefully selected healthy adults. In 75 per cent of the test subjects bacterial organisms were cultured. However, growth was often poor and the predominant species suggest a commensal flora: coagulase-negative staphylococci were retrieved from 35 per cent, Corynebacterium sp. from 23 per cent and Staphyloccus aureus from eight per cent of the adults. These data are very different from those previously obtained among children where – even in the absence of obvious ENT pathology – the most frequently cultured organisms were typical sinusitis pathogens: Haemophilus influenzae present in 40 per cent, Moraxella catarrhalis in 34 per cent and Streptococcus pneumoniae in 50 per cent of children. Furthermore, Streptococcus viridans and Neisseria sp., both organisms that might be able to inhibit colonization by some of the pathogens and found commonly among children, are virtually absent in healthy adults.

scholarly journals RESPONSE OF CITRIC ACID LEVELS TO ORAL ADMINISTRATION OF GLUCOSE. I. NORMAL ADULTS AND CHILDREN 1

1948 ◽  
Vol 27 (4) ◽  
pp. 446-449 ◽  
Author(s):  
Samuel Natelson ◽  
Joseph B. Pincus ◽  
Julius K. Lugovoy
Keyword(s):  
Citric Acid ◽  
Oral Administration ◽  
Adults And Children ◽  
Normal Adults

scholarly journals A study of the crowding phenomenon using the Landolt Ring Crowded Card in normal adults and children.

1999 ◽  
Vol 27 ◽  
pp. 241-245
Author(s):  
Fumiko Matsumoto ◽  
Akemi Wakayama ◽  
Kazuyo Ohmure ◽  
Kyoko Tanoue ◽  
Toshifumi Otori ◽  
...  
Keyword(s):  
Adults And Children ◽  
Landolt Ring ◽  
Normal Adults

scholarly journals Serum Concentrations of Vitamin D, Calcium, Phosphorus and Trace Minerals in Adults and Children with Haemophilia A: Association with Disease Severity, Quality of Life, Joint Health and Functional Status

2020 ◽  
Author(s):  
Amir Abbasnezhad ◽  
Mehdi Habibi ◽  
Babak Abdolkarimi ◽  
Soodabeh Zare ◽  
Ezatollah Fazeli Moghadam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Vitamin D ◽  
Serum Levels ◽  
Haemophilia A ◽  
Serum Concentrations ◽  
Joint Health ◽  
Adults And Children ◽  
Lower Physical Activity

Background: To investigate the serum levels of 25(OH)D and minerals in adults and children with haemophilia A, and the possible association of these factors with Pediatric Haemophilia/Haemophilia Activities List (PedHAL/HAL), Haemophilia Joint Health Score (HJHS) and Haemophilia-specific quality of life (QoL) index this case-control study was conducted. Materials and Methods: Eighty five haemophilia A patients (HP) registered in Hemophilia Society of Lorestan province were recruited. Along with HP, sex and age matched healthy controls (HCs) were recruited. Linear regression was used to evaluate the possible relation between biochemical factors and other variables. One-way analysis of variance (ANOVA) was used to compare the biochemical factors between three or more independent groups. Results: Results indicated that serum zinc, phosphorus and magnesium were significantly lower, whereas, serum level of alkaline phosphatase (ALP) was statistically higher in HP compared with HCs. Other biochemical factors including calcium and parathyroid hormone (PTH) were not different between groups. Serum 25(OH) D was lower only in children with haemophilia and not in adults. Percentage of subjects who were vitamin D deficient was higher in HP vs. HCs (57.6% vs. 35.3%), and also this rate was higher in children with haemophilia vs. adults (77.8% vs. 48.3%). Lower serum concentrations of assessed minerals and vitamin D were associated with lower physical activity, poor QoL and worst joint health, and these associations were stronger in children. Conclusion: Present study indicated that serum levels of vitamin D and minerals were low in HP, and these low levels were associated with poor QoL, lower physical activity and worst joint health.

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