Dietary ascorbic acid, pyridoxine and riboflavin reduce the light sensitivity of larvae and pupae of Drosophila melanogaster

1991 ◽  
Vol 21 (5) ◽  
pp. 541-544 ◽  
Author(s):  
B.G. Bruins ◽  
W. Scharloo ◽  
G.E.W. Thörig
Keyword(s):  
Ascorbic Acid ◽  
Drosophila Melanogaster ◽  
Light Sensitivity

scholarly journals Amaranth Leaf Extract Protects Against Hydrogen Peroxide Induced Oxidative Stress in Drosophila Melanogaster

2021 ◽  
Author(s):  
Johnmark Ndinawe ◽  
Hellen W. Kinyi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Antioxidant Activity ◽  
Ascorbic Acid ◽  
Drosophila Melanogaster ◽  
Leaf Extract ◽  
Dependent Manner ◽  
Polyphenol Compounds ◽  
Dose Dependent

Abstract ObjectiveAmaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H2O2 induced oxidative stress in Drosophila melanogaster flies was assessed.ResultsConsumption of Amaranth leaf extract was associated with increased survival on exposure to H202 in a dose dependent manner in Drosophila melanogaster flies.

scholarly journals Controlling the behaviour of Drosophila melanogaster via smartphone optogenetics

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ilenia Meloni ◽  
Divya Sachidanandan ◽  
Andreas S. Thum ◽  
Robert J. Kittel ◽  
Caroline Murawski
Keyword(s):  
Drosophila Melanogaster ◽  
Low Cost ◽  
Model Organism ◽  
Light Sensitivity ◽  
Light Sources ◽  
Neuronal Populations ◽  
Non Invasive ◽  
Invertebrate Species ◽  
Temporal And Spatial ◽  
Stimulation Of

Abstract Invertebrates such as Drosophila melanogaster have proven to be a valuable model organism for studies of the nervous system. In order to control neuronal activity, optogenetics has evolved as a powerful technique enabling non-invasive stimulation using light. This requires light sources that can deliver patterns of light with high temporal and spatial precision. Currently employed light sources for stimulation of small invertebrates, however, are either limited in spatial resolution or require sophisticated and bulky equipment. In this work, we used smartphone displays for optogenetic control of Drosophila melanogaster. We developed an open-source smartphone app that allows time-dependent display of light patterns and used this to activate and inhibit different neuronal populations in both larvae and adult flies. Characteristic behavioural responses were observed depending on the displayed colour and brightness and in agreement with the activation spectra and light sensitivity of the used channelrhodopsins. By displaying patterns of light, we constrained larval movement and were able to guide larvae on the display. Our method serves as a low-cost high-resolution testbench for optogenetic experiments using small invertebrate species and is particularly appealing to application in neuroscience teaching labs.

scholarly journals Exquisite Light Sensitivity of Drosophila melanogaster Cryptochrome

PLoS Genetics ◽  
2013 ◽  
Vol 9 (7) ◽  
pp. e1003615 ◽  
Author(s):  
Pooja Vinayak ◽  
Jamie Coupar ◽  
S. Emile Hughes ◽  
Preeya Fozdar ◽  
Jack Kilby ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Light Sensitivity

Exploring hazards of acute exposure of Acephate in Drosophila melanogaster and search for l-ascorbic acid mediated defense in it

2017 ◽  
Vol 321 ◽  
pp. 690-702 ◽  
Author(s):  
Prem Rajak ◽  
Moumita Dutta ◽  
Salma Khatun ◽  
Moutushi Mandi ◽  
Sumedha Roy
Keyword(s):  
Ascorbic Acid ◽  
Drosophila Melanogaster ◽  
Acute Exposure

Paraquat-induced Oxidative Stress in Drosophila melanogaster: Effects of Melatonin, Glutathione, Serotonin, Minocycline, Lipoic Acid and Ascorbic Acid

2006 ◽  
Vol 31 (12) ◽  
pp. 1425-1432 ◽  
Author(s):  
Ernesto Bonilla ◽  
Shirley Medina-Leendertz ◽  
Virginia Villalobos ◽  
Leunardy Molero ◽  
Aquiles Bohórquez
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Drosophila Melanogaster ◽  
Lipoic Acid

scholarly journals Regulation of phototransduction responsiveness and retinal degeneration by a phospholipase D–generated signaling lipid

2005 ◽  
Vol 169 (3) ◽  
pp. 471-479 ◽  
Author(s):  
Mary M. LaLonde ◽  
Hilde Janssens ◽  
Erica Rosenbaum ◽  
Seok-Yong Choi ◽  
J. Peter Gergen ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Phosphatidic Acid ◽  
Retinal Degeneration ◽  
Phospholipase D ◽  
Light Sensitivity ◽  
Low Light ◽  
Lipid Modifications ◽  
Visual Signaling ◽  
Transfer Protein ◽  
Light Stimuli

Drosophila melanogaster phototransduction proceeds via a phospholipase C (PLC)–triggered cascade of phosphatidylinositol (PI) lipid modifications, many steps of which remain undefined. We describe the involvement of the lipid phosphatidic acid and the enzyme that generates it, phospholipase D (Pld), in this process. Pldnull flies exhibit decreased light sensitivity as well as a heightened susceptibility to retinal degeneration. Pld overexpression rescues flies lacking PLC from light-induced, metarhodopsin-mediated degeneration and restores visual signaling in flies lacking the PI transfer protein, which is a key player in the replenishment of the PI 4,5-bisphosphate (PIP2) substrate used by PLC to transduce light stimuli into neurological signals. Altogether, these findings suggest that Pld facilitates phototransduction by maintaining adequate levels of PIP2 and by protecting the visual system from metarhodopsin-induced, low light degeneration.

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