Maternal and fetal prostaglandin concentrations during late gestation in dairy cattle

1993 ◽  
Vol 45 (1) ◽  
pp. 35-46 ◽  
Author(s):  
W. Heuwieser ◽  
E. Grunert ◽  
H.O. Hoppen
Keyword(s):  
2004 ◽  
Vol 87 (12) ◽  
pp. 4269-4277 ◽  
Author(s):  
M.A. Bryan ◽  
M.T. Socha ◽  
D.J. Tomlinson

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Lorraine M. Sordillo

Uncontrolled or impaired immune and inflammatory responses in periparturient dairy cows are associated with increased incidence and severity of infectious diseases. The progressive development of oxidative stress during the transition from late gestation to peak lactation is thought to be a significant underlying factor leading to dysfunctional immune cell responses. Certain trace minerals, such as selenium (Se), can ameliorate oxidative stress and reduce the severity of several economically important diseases in dairy cattle including mastitis and metritis. Many of the health benefits of Se can be attributed to the antioxidant functions of selenoproteins. Changes in selenoprotein activity as a consequence of Se nutritional status can directly alter a number of critical cellular functions involved in the inflammatory response. A better understanding of how Se can optimize immune cell responses may facilitate the design of nutritional regimes that will reduce health disorders during the periparturient period.


Antioxidants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1555
Author(s):  
Jianxin Xiao ◽  
Muhammad Zahoor Khan ◽  
Yulin Ma ◽  
Gibson Maswayi Alugongo ◽  
Jiaying Ma ◽  
...  

Dairy cattle experience health risks during the periparturient period. The continuous overproduction of reactive oxygen species (ROS) during the transition from late gestation to peak lactation leads to the development of oxidative stress. Oxidative stress is usually considered the main contributor to several diseases such as retained placenta, fatty liver, ketosis, mastitis and metritis in periparturient dairy cattle. The oxidative stress is generally balanced by the naturally available antioxidant system in the body of dairy cattle. However, in some special conditions, such as the peripariparturient period, the natural antioxidant system of a body is not able to balance the ROS production. To cope with this situation, the antioxidants are supplied to the dairy cattle from external sources. Natural antioxidants such as selenium and vitamin E have been found to restore normal health by minimizing the harmful effects of excessive ROS production. The deficiencies of Se and vitamin E have been reported to be associated with various diseases in periparturient dairy cattle. Thus in the current review, we highlight the new insights into the Se and vitamin E supplementation as antioxidant agents in the health regulation of periparturient dairy cattle.


2020 ◽  
Vol 103 (1) ◽  
pp. 714-722
Author(s):  
R.A.C. Barraclough ◽  
D.J. Shaw ◽  
R. Boyce ◽  
M.J. Haskell ◽  
A.I. Macrae
Keyword(s):  

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 146-147
Author(s):  
Dave J Seymour ◽  
Michelle Carson ◽  
Jean-Baptiste Daniel ◽  
Victoria Sanz ◽  
Javier Martín-Tereso ◽  
...  

Abstract Fat-embedded calcium gluconate fed as a dietary supplement has previously been shown to increase milk and component yields in lactating dairy cattle in controlled experimental settings. These responses are thought to be due to improvements in gut barrier function and health driven by increased butyrate supply from the fermentation of calcium gluconate in the hindgut. The objectives of the current study were to validate the effects of a fat-embedded calcium gluconate supplement offered during late gestation and early lactation on milk production and milk component yields in a commercial setting. From April to December 2019, 151 multiparous Holstein-Friesian dairy cows were assigned to one of four treatment sequences in a randomized complete block design within a 2 x 2 factorial design (negative control or supplement prepartum, and negative control or supplement postpartum). Outcomes pertaining to milk production, component yields and health parameters were recorded for the first 100 days of lactation. Yields of milk and all components increased (P ≤ 0.045) in response to postpartum supplementation, in agreement with previous studies. Milk protein content was 0.03% lower (P = 0.003) in animals receiving the supplement prepartum. Additionally, prepartum supplementation diminished the lactation performance response relative to animals receiving supplementation in the postpartum period only; lactation performance was partially ameliorated by subsequent postpartum supplementation. Overall, these results support previous work examining the lactation performance response to fat-embedded calcium gluconate supplementation in dairy cattle. Future controlled studies examining the effects of prepartum supplementation on subsequent lactation performance are warranted.


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