Feasibility studies of a reflex transmission imaging method

1990 ◽  
Vol 12 (2) ◽  
pp. 148-149
Author(s):  
I Yamada
2021 ◽  
Vol 11 (11) ◽  
pp. 5219
Author(s):  
Yosuke Sakurai ◽  
Hirotaka Sato ◽  
Nozomu Adachi ◽  
Satoshi Morooka ◽  
Yoshikazu Todaka ◽  
...  

As a new method for evaluating single crystals and oligocrystals, pulsed neutron Bragg-dip transmission analysis/imaging method is being developed. In this study, a single Bragg-dip profile-fitting analysis method was newly developed, and applied for analyzing detailed inner information in a crystalline grain position-dependently. In the method, the spectrum profile of a single Bragg-dip is analyzed at each position over a grain. As a result, it is expected that changes in crystal orientation, mosaic spread angle and thickness of a perfect crystal can be evaluated from the wavelength, the width and the integrated intensity of the Bragg-dip, respectively. For confirming this effectiveness, the method was applied to experimental data of position-dependent Bragg-dip transmission spectra of a Si-steel plate consisting of oligocrystals. As a result, inner information of multiple crystalline grains could be visualized and evaluated. The small change in crystal orientation in a grain, about 0.4°, could be observed by imaging the Bragg-dip wavelengths. By imaging the Bragg-dip widths, both another grain and mosaic block in a grain were detected. Furthermore, imaging results of the integrated intensities of Bragg-dips were consistent with the results of Bragg-dip width imaging. These small crystallographic changes have not been observed and visualized by previous Bragg-dip analysis methods.


2020 ◽  
Vol 53 (1) ◽  
pp. 188-196 ◽  
Author(s):  
Chiara Carminati ◽  
Markus Strobl ◽  
Triestino Minniti ◽  
Pierre Boillat ◽  
Jan Hovind ◽  
...  

4D wavelength-resolved neutron tomography of a reference sample made of several polycrystalline materials, namely nickel, iron, titanium, lead, copper and aluminium, is presented. Data were acquired using the time-of-flight transmission imaging method at the IMAT beamline at the ISIS pulsed neutron source. Wavelength-dispersive tomography reconstruction was computed using filtered back projection, allowing wavelength-resolved total-cross-section retrieval for each voxel in the reconstructed volume of the sample. The need for background correction to enable quantitative results and analysis is discussed, and the achieved 3D spatial resolution with respect to the obtained Bragg-edge pattern quality is investigated.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1829.2-1829
Author(s):  
A. Blanken ◽  
C. J. Van der Laken ◽  
M. Nurmohamed

Background:Optical spectral transmission imaging (OST) is a new imaging method that measures inflammation in the hands of rheumatoid arthritis (RA) patients. OST might be used to assess disease activity instead of disease activity score 28 (DAS28) or ultrasonography (US). The advantage of OST is that it is fast and not operator dependent. Up to now OST has only been investigated cross-sectionally and it is unknown if and to what extent OST can detect inflammatory changes due to anti-inflammatory treatment for RA.Objectives:To compare OST measurements before and after 1 month of biological treatment for RA and to compare these OST changes with changes on US and disease activity.Methods:The HandScan device from Hemics, the Netherlands, was used to measure OST scores for 13 RA patients before and after 1 month of anti-inflammatory therapy. Treatment included tumor necrosis factor inhibitor (n=10), tocilizumab (n=2) and tofacitinib (n=1). OST scores range from 0-66 (one score for both hands) and are based on bilateral wrist, MCP and PIP joints. US was performed in the same joints as OST and semi-quantitatively scored on a scale of 0-3 for grey-scale (GS) synovitis and power Doppler (PD) signal. Joint scores of GS synovitis or PD were summed, resulting is a total GS synovitis score and a total PD score, both also ranging from 0-66. Furthermore, tender joint count 28 (TJC28), swollen joint count 28 (SJC28), DAS28, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were determined. Response to therapy was defined as achieving the minimal clinically interesting improvement of DAS28 (DAS28 difference after 1 month > -1) as proposed by Ward et al. [1]Results:Baseline OST was 17.73 ± 6.10 and this significantly decreased to 16.01 ± 6.68 (difference -1.71, 95%CI 0.05-3.38, p=0.045) after 1 month of therapy. This decrease was only present in patients who responded to therapy (n=8; OST decreased from 17.24 ± 5.98 to 14.26 ± 5.65, p=0.01) and not in non-responders (n=5; OST increased from 18.52 ± 6.90 to 18.83 ± 7.87, p=0.03).In the total group, also DAS28 (difference -1.59, 95%CI 0.74-2.45, p=0.002), SJC28 (difference 4.62, 95%CI 1.50-7.73, p=0.007), ESR (Wilcoxon Rank p=0.008) and CRP (Wilcoxon Rank p=0.03) significantly decreased after 1 month of therapy, but TJC28 did not (difference 2.62, 95%CI -2.7-7.91, p=0.30).OST change after 1 month of therapy significantly correlated with TCJ28 change (table 1). For GS synovitis the correlation coefficient nearly reached statistical significance. Changes in all other disease activity parameters were not correlated with OST change.Table 1.Correlation of change in OST measurement with change in disease activity after 1 months of anti-inflammatory therapySpearman rp-valueTotal GS synovitis0.540.06Total PD0.220.47DAS280.350.25SJC280.290.33TJC280.630.02ESR-0.420.15CRP-0.230.45Conclusion:OST scores significantly decreased after 1 month of anti-inflammatory therapy and only in the RA group that responded well to this therapy. This indicates that OST is capable of detecting therapy induced inflammatory changes in the hands of RA patients. Larger studies are needed to further assess the monitoring value of OST for therapy efficacy in RA patients.References:[1]Ward et al. 2015 Clinically important changes in individual and composite measures of rheumatoid arthritis activity: thresholds applicable in clinical trials. Ann Rheum Dis 74(9): p. 1691-6.Disclosure of Interests:Annelies Blanken: None declared, C.J. van der Laken: None declared, Michael Nurmohamed Grant/research support from: Not related to this research, Consultant of: Not related to this research, Speakers bureau: Not related to this research


1985 ◽  
Vol 7 (3) ◽  
pp. 201-214 ◽  
Author(s):  
Philip S. Green ◽  
Marcel Arditi

Reflex Transmission Imaging (RTI) is a new imaging method by which orthographic transmission images can be made using augmented B-mode equipment. Conventional transmission imaging requires acoustic coupling to large areas on both sides of the body, whereas RTI can be performed from one side with a single, small transducer probe. In this mode, transmission images in a plane normal to the beam are made by integrating the reverberations from beyond the focal zone of the transducer. These reverberations provide, in essence, a source of incoherent insonification from behind the focal plane. Preliminary in-vitro images have been made using a computer-interfaced rectilinear scanner with a 1-inch diameter f/2.8 transducer. The images have good resolution and signal-to-noise ratio, and a short depth-of-field. Backscatterer inhomogeneity is well smoothed. Transmission images provide information that is complementary to B-scans. RTI will allow both to be made with the same instrument and presented on the same display. A time-gated reflection C-scan could be generated simultaneously. Other RTI modes, including an attenuation B-mode, also are discussed.


Geophysics ◽  
2019 ◽  
Vol 84 (2) ◽  
pp. S71-S82 ◽  
Author(s):  
Chris Willacy ◽  
Maksym Kryvohuz

The imaging of steep salt boundaries has received much attention with the advent of improved wider azimuth acquisition designs and advanced imaging techniques such as reverse time migration (RTM), for example. However, despite these advancements in capability, there are cases in which the salt boundary is either poorly illuminated or completely absent in the migrated image. To provide a solution to this problem, we have developed two RTM methods for imaging salt boundaries, which use transmitted wavefields. In the first technique, downgoing waves, typically recorded in walkaway vertical seismic profile surveys, are used to image the salt flank via the generation of aplanatic isochrones. This image can be generated in the absence of an explicit interpretation of the salt flank using dual migration velocity models, as demonstrated on a 3D walkaway field data set from the Gulf of Mexico. In the second technique, we extend the basic theory to include imaging of upgoing source wavefields, which are transmitted at the base salt from below, as acquired by a surface acquisition geometry. This technique has similarities to the prism-imaging method, yet it uses transmitted instead of reflected waves at the salt boundary. Downgoing and upgoing methods are shown to satisfactorily generate an image of the salt flank; however, transmission imaging can create artifacts if reflection arrivals are included in the migration or the acquisition geometry is limited in extent. Increased wavelet stretch is also observed due to the higher transmission coefficient. An important benefit of these methods is that transmission imaging produces an opposite depth shift to errors in the velocity model compared with imaging of reflections. When combined with conventional seismic reflection surveys, this behavior can be used to provide a constraint on the accuracy of the salt and/or subsalt velocities.


Author(s):  
T. Y. Tan ◽  
W. K. Tice

In studying ion implanted semiconductors and fast neutron irradiated metals, the need for characterizing small dislocation loops having diameters of a few hundred angstrom units usually arises. The weak beam imaging method is a powerful technique for analyzing these loops. Because of the large reduction in stacking fault (SF) fringe spacing at large sg, this method allows for a rapid determination of whether the loop is faulted, and, hence, whether it is a perfect or a Frank partial loop. This method was first used by Bicknell to image small faulted loops in boron implanted silicon. He explained the fringe spacing by kinematical theory, i.e., ≃l/(Sg) in the fault fringe in depth oscillation. The fault image contrast formation mechanism is, however, really more complicated.


Author(s):  
K. A. Brookes ◽  
D. Finbow ◽  
Madeleine Samuel

Investigation of the particulate matter contained in the water sample, revealed the presence of a number of different types and certain of these were selected for analysis.An A.E.I. Corinth electron microscope was modified to accept a Kevex Si (Li) detector. To allow for existing instruments to be readily modified, this was kept to a minimum. An additional port is machined in the specimen region to accept the detector, with the liquid nitrogen cooling dewar conveniently housed in the left hand cupboard adjacent to the microscope column. Since background radiation leads to loss in the sensitivity of the instrument, great care has been taken to reduce this effect by screening and manufacturing components that are near the specimen from material of low atomic number. To change from normal transmission imaging to X-ray analysis, the special 4-position specimen rod is inserted through the normal specimen airlock.


Author(s):  
Steve Lindaas ◽  
Chris Jacobsen ◽  
Alex Kalinovsky ◽  
Malcolm Howells

Soft x-ray microscopy offers an approach to transmission imaging of wet, micron-thick biological objects at a resolution superior to that of optical microscopes and with less specimen preparation/manipulation than electron microscopes. Gabor holography has unique characteristics which make it particularly well suited for certain investigations: it requires no prefocussing, it is compatible with flash x-ray sources, and it is able to use the whole footprint of multimode sources. Our method serves to refine this technique in anticipation of the development of suitable flash sources (such as x-ray lasers) and to develop cryo capabilities with which to reduce specimen damage. Our primary emphasis has been on biological imaging so we use x-rays in the water window (between the Oxygen-K and Carbon-K absorption edges) with which we record holograms in vacuum or in air.The hologram is recorded on a high resolution recording medium; our work employs the photoresist poly(methylmethacrylate) (PMMA). Following resist “development” (solvent etching), a surface relief pattern is produced which an atomic force microscope is aptly suited to image.


Author(s):  
Akira Tonomura

Electron holography is a two-step imaging method. However, the ultimate performance of holographic imaging is mainly determined by the brightness of the electron beam used in the hologram-formation process. In our 350kV holography electron microscope (see Fig. 1), the decrease in the inherently high brightness of field-emitted electrons is minimized by superposing a magnetic lens in the gun, for a resulting value of 2 × 109 A/cm2 sr. This high brightness has lead to the following distinguished features. The minimum spacing (d) of carrier fringes is d = 0.09 Å, thus allowing a reconstructed image with a resolution, at least in principle, as high as 3d=0.3 Å. The precision in phase measurement can be as high as 2π/100, since the position of fringes can be known precisely from a high-contrast hologram formed under highly collimated illumination. Dynamic observation becomes possible because the current density is high.


Sign in / Sign up

Export Citation Format

Share Document