Daily plasma estradiol and progesterone levels over the menstrual cycle and their relation to premenstrual symptoms

1995 ◽  
Vol 20 (3) ◽  
pp. 259-267 ◽  
Author(s):  
E Redei
1991 ◽  
Vol 125 (2) ◽  
pp. 132-137 ◽  
Author(s):  
Stefan Hammarbäk ◽  
Ulla-Britt Ekholm ◽  
Torbjörn Bäckström

Abstract. In the premenstrual syndrome the negative symptoms appear during the luteal phase of the menstrual cycle. Ovulation and the formation of a corpus luteum seem to be of great importance in precipitating the syndrome. In a large group of women with premenstrual syndrome investigated daily with symptom ratings and weekly plasma estradiol and progesterone assays, 8 were found to have one ovulatory and one spontaneously occurring anovulatory menstrual cycle. In both these cycles, the post- and premenstrual phases were compared by testing for recurrence of symptoms. All patients showed a highly significant cyclical worsening of negative premenstrual symptoms during the ovulatory cycles, whereas in the anovulatory cycles the cyclical symptoms disappeared, resulting in relief of the premenstrual syndrome. These results support earlier hypotheses, suggesting that the premenstrual syndrome appears as a result of provoking factors produced by the corpus luteum. This view is in line with earlier therapeutic findings showing that induced anovulation can relieve the premenstrual syndrome.


1976 ◽  
Vol 43 (2) ◽  
pp. 436-445 ◽  
Author(s):  
CHUNG-HSIU WU ◽  
TORU MOTOHASHI ◽  
HANY ALY ABDEL-RAHMAN ◽  
GEORGE L. FLICKINGER ◽  
GEORGE MIKHAIL

1995 ◽  
Vol 25 (5) ◽  
pp. 947-955 ◽  
Author(s):  
M. Mira ◽  
S. Abraham ◽  
D. McNeil ◽  
J. Vizzard ◽  
P. Macaskill ◽  
...  

SYNOPSISThe prospective symptom reports of women seeking treatment for premenstrual symptoms and control subjects were investigated. In order to compare symptom reports from premenstrual symptom sufferers and control subjects a method of combining and analysing prospectively collected menstrual cycle symptom data is required. A technique that uses the time of onset of menses and the time of ovulation (as measured by urinary luteinizing hormone excretion) to standardize each cycle into 14 time points was developed. Summary factors were then empirically derived from data collected prospectively from 30 premenstrual symptom sufferers and 19 control subjects. Twenty-two mood symptoms were summarized into a single factor and the 29 most frequently occurring physical symptoms were summarized into two factors. Factor scores were calculated on the basis of these factors and the effect of time during the menstrual cycle on these scores examined. Both physical symptom factor scores increased significantly in the luteal phase for both the premenstrual symptom sufferer group and the control group. The single mood factor score increased significantly in the luteal phase for the premenstrual symptom sufferer group but not for the control group, suggesting that the only qualitative difference between the groups was the presence of cyclic mood symptoms in the premenstrual symptom sufferer group. The premenstrual symptom sufferer group recorded significantly higher scores on each of the three factors than the control group. The correlation between the scores on each of the factors over three cycles was high both in the follicular and luteal phase suggesting that these factor scores provide a reproducible measure of menstrual cycle symptomatology.


1992 ◽  
Vol 71 (1) ◽  
pp. 247-252 ◽  
Author(s):  
Helen Lindner ◽  
Robert J. Kirkby

104 women, between the ages of 18 and 45 years, were surveyed to investigate the relationship between premenstrual symptomatology, as measured by the Modified Menstrual Distress Questionnaire, and irrational thinking, as measured by the General Attitude and Belief Scale. The women who reported greater premenstrual symptomatology also reported significantly higher scores in the “need for comfort” irrationality subscale. This indicated that these women had particular difficulty dealing with hassles and the resulting feelings of tension and irritability in the premenstruum. It was suggested that the absence of significant effects for other rationality-irrationality subscales could be associated with testing at different times during the menstrual cycle. Irrationality, like other conditions (such as anxiety and depression) prevalent in the premenstruum, could change in intensity across phases of the menstrual cycle.


Author(s):  
Sally King

Abstract King’s chapter begins by describing the historical context of ‘premenstrual’ symptoms, which were first formally described in 1931. She then questions the prioritization of mood-based symptoms in the diagnostic criteria for Premenstrual Syndrome (PMS). King argues that population studies suggest that mood-based symptoms are not the most common nor most disruptive of menstrual changes. She then proposes that the trend of ‘psychologizing’ premenstrual symptoms is influenced by the sexist historical assumption of ‘the myth of the irrational female’—the idea that women, due to their reproductive biology, are pathologically emotional and thus have a reduced capacity for reason. The author concludes by calling for a more integrated and rigorous approach to PMS definitions and research to support people who experience cyclical symptoms, without unintentionally pathologizing the menstrual cycle or stigmatizing an entire gender.


1970 ◽  
Vol 3 (2) ◽  
pp. 43-59
Author(s):  
Miguel da Silva Diniz ◽  
Andreza Cristina Souza Lima ◽  
Hildebrando Pereira ◽  
Gislene Ferreira

Objetivos: Avaliar a presença da síndrome pré-menstrual (SPM) e sua intensidade, bem como os principais sintomas relacionados em acadêmicas do curso de medicina da Faculdade de Medicina de Itajubá. Materiais e Métodos: Foi realizado um inquérito com mulheres que ingressaram no curso entre os anos de 2005 a 2011, através de um questionário em que as acadêmicas eram classificadas de acordo com a intensidade dos sintomas de SPM e agrupadas em um tipo de sintoma principal. Resultados e Discussão: A ocorrência da SPM foi observada em 100% das acadêmicas entrevistadas em todos os anos, independentemente da série, ou seja, todas as acadêmicas apresentaram algum sintoma, mesmo que leve, da SPM.  No entanto, o 2° ano letivo foi o que teve a maior média de sintomas (média de 41,7 pontos) da SPM, e o 6°, a menor (média de 36,1). Quanto às características de sintomas das acadêmicas, as manifestações mais citadas foram a irritabilidade e compulsividade. Conclusão: A alta prevalência da SPM foi observada em todos os anos entrevistados, indo de encontro com a literatura, que indica a presença da síndrome em mulheres de todo o mundo, tornando necessária a existência de estudos que facilitem o diagnostico precoce com seu respectivo tratamento mais adequado, reduzindo seus efeitos no cotidiano das mulheres.   Palavras-chave: Síndrome pré-menstrual, ciclo menstrual, sintomas pré-menstruais. ABSTRACTObjectives: To evaluate the presence of Premenstrual syndrome (PMS) and its intensity, as well as major academic-related symptoms in the course of medicine at Medical College of Itajubá. Materials and Methods: A survey was conducted with women who entered the course between the years 2005 to 2011, through a questionnaire the students were classified according to the intensity of the symptoms of PMS and grouped into one type of symptom page. Results and Discussion: The occurrence of PMS was observed in 100% of academic respondents in every year, regardless of the series, all academic exhibited some symptoms, even mild PMS. However, the 2nd year was academic year that had the highest average number of symptoms (mean 41,7 points) of PMS, and the sixth year, the lowest (average 36,1). Regarding the characteristics of academic symptoms, the most mentioned manifestations were the irritability and compulsiveness. Conclusion: A high prevalence of PMS was observed in all the years surveyed, in agreement with the literature, which indicates the presence of the syndrome in women worldwide, showing the need of studies that facilitate early diagnosis with their respective more appropriate treatment, reducing its effects on the daily lives of women. Keywords: Premenstrual syndrome, menstrual cycle, premenstrual symptoms. 


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