Application of triple quadrupole tandem mass spectrometry to the analysis of pyridine-containing derivatives of long-chain acids and alcohols

1992 ◽  
Vol 579 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Federico Maria Rubino ◽  
Luigi Zecca
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Triple Quadrupole ◽  
Derivatives Of ◽  
Long Chain

scholarly journals Discovery of Unexpected Sphingolipids in Almonds and Pistachios with an Innovative Use of Triple Quadrupole Tandem Mass Spectrometry

Foods ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 110 ◽  
Author(s):  
Federico Maria Rubino ◽  
Michele Dei Cas ◽  
Monica Bignotto ◽  
Riccardo Ghidoni ◽  
Marcello Iriti ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Neutral Loss ◽  
Spectrometric Method ◽  
Total Lipid Extract ◽  
Tandem Mass ◽  
Mass Spectrometric Method ◽  
Triple Quadrupole ◽  
Loss Experiment ◽  
Long Chain

The densely packed storage of valuable nutrients (carbohydrates, lipids, proteins, micronutrients) in the endosperm of nuts and seeds makes the study of their complex composition a topic of great importance. Ceramides in the total lipid extract of some ground almonds and pistachios were searched with a systematic innovative discovery precursor ion scan in a triple quadrupole tandem mass spectrometry, where iso-energetic collision activated dissociation was performed. Five descriptors were used to search components with different C18 long chain bases containing different structural motifs (d18:0, d18:1, d18:2, t18:0, t18:1). The presence of hexoside unit was screened with a specific neutral loss experiment under iso-energetic collision activated dissociation conditions. The discovery scans highlighted the presence of two specific hexosyl-ceramides with a modified sphingosine component (d18:2) and C16:0 or C16:0 hydroxy-fatty acids. The hexosyl-ceramide with the non-hydroxylated fatty acid seemed specific of pistachios and was undetected in almonds. The fast and comprehensive mass spectrometric method used here can be useful to screen lipid extracts of several more seeds of nutraceutical interest, searching for unusual and/or specific sphingosides with chemically decorated long chain bases.

Determination of the antiretroviral drug tenofovir in plasma from HIV-infected adults by ultrafast isotope dilution MALDI-triple quadrupole tandem mass spectrometry

2011 ◽  
Vol 46 (3) ◽  
pp. 282-289 ◽  
Author(s):  
Roland J. W. Meesters ◽  
Jeroen J. A. van Kampen ◽  
Rachel D. Scheuer ◽  
Marchina E. van der Ende ◽  
Rob A. Gruters ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Isotope Dilution ◽  
Tandem Mass ◽  
Triple Quadrupole ◽  
Antiretroviral Drug

Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides

2007 ◽  
Vol 1159 (1-2) ◽  
pp. 119-124 ◽  
Author(s):  
Györgyi Ferenc ◽  
Petra Pádár ◽  
Tamás Janáky ◽  
Zoltán Szabó ◽  
Gábor K. Tóth ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Derivatives Of
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