Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: a 20-year follow-up of the lipid research clinics prevalence study

Although the efficacy of cardiac rehabilitation (CR) is proven, the need to improve patients’ adherence has emerged. There are only a few studies that have investigated the effect of sending text messages after a CR period to stimulate subjects’ ongoing engagement in regular physical activity (PA). A randomized controlled pilot trial was conducted after CR, sending a daily PA text message reminder to an intervention group (IG), which was compared with a usual care control group (CG) during three months of follow-up. Thirty-two subjects were assessed pre- and post-study intervention with GPAQ, submaximal iso-watt exercise testing, a 30 s sit-to-stand test, a bilateral arm curl test, and a final survey on a seven-point Likert scale. A statistically significant difference in the increase of moderate PA time (Δ 244.7 (95% CI 189.1, 300.4) minutes, p < 0.001) and in the reduction of sedentary behavior time (Δ −77.5 (95% CI 104.9, −50.1) minutes, p = 0.004) was shown when the IG was compared with the CG. This was associated with an improvement in heart rate, blood pressure, and patients’ Borg rating on the category ratio scale 10 (CR10) in iso-watt exercise testing (all p < 0.05). Furthermore, only the IG did not show a worsening of the strength parameters in the follow-up leading to a change of the 30 s sit-to-stand test with a difference of +2.2 (95% CI 1.23, 3.17) repetitions compared to CG (p = 0.03). The telemedical intervention has been appreciated by the IG, whose willingness to continue with regular PA emerged to be superior compared to the CG. Text messages are an effective and inexpensive adjuvant after phase 2 CR that improves adherence to regular PA. Further studies are needed to confirm these results in a larger patient population and in the long term.

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Metabolic Syndrome in Childhood Predicts Adult Cardiovascular Disease 25 Years Later: The Princeton Lipid Research Clinics Follow-up Study

Yearbook of Pediatrics ◽

10.1016/s0084-3954(08)79000-6 ◽

2009 ◽

Vol 2009 ◽

pp. 222-225

Author(s):

J.A. Stockman

Keyword(s):

Cardiovascular Disease ◽

Metabolic Syndrome ◽

Lipid Research ◽

Follow Up Study

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Long‐Term Cardiac Function After Peripartum Cardiomyopathy and Preeclampsia: A Danish Nationwide, Clinical Follow‐Up Study Using Maximal Exercise Testing and Cardiac Magnetic Resonance Imaging

Journal of the American Heart Association ◽

10.1161/jaha.118.008991 ◽

2018 ◽

Vol 7 (20) ◽

Cited By ~ 7

Author(s):

Anne S. Ersbøll ◽

Annemie S. Bojer ◽

Maria G. Hauge ◽

Marianne Johansen ◽

Peter Damm ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Cardiac Magnetic Resonance ◽

Magnetic Resonance ◽

Exercise Testing ◽

Maximal Exercise ◽

Peripartum Cardiomyopathy ◽

Resonance Imaging ◽

Follow Up Study

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The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality

European Journal of Preventive Cardiology ◽

10.1177/2047487318804618 ◽

2018 ◽

Vol 26 (2) ◽

pp. 199-207 ◽

Cited By ~ 11

Author(s):

Esko Salokari ◽

Jari A Laukkanen ◽

Terho Lehtimaki ◽

Sudhir Kurl ◽

Setor Kunutsor ◽

...

Keyword(s):

Exercise Capacity ◽

Exercise Testing ◽

Cardiovascular Mortality ◽

Cox Regression ◽

Cardiovascular Death ◽

Bicycle Exercise ◽

Metabolic Equivalents ◽

Ergometer Exercise ◽

Duke Treadmill Score

Background The Duke treadmill score, a widely used treadmill testing tool, is a weighted index combining exercise time or capacity, maximum ST-segment deviation and exercise-induced angina. No previous studies have investigated whether the Duke treadmill score and its individual components based on bicycle exercise testing predict cardiovascular death. Design Two populations with a standard bicycle testing were used: 3936 patients referred for exercise testing (2371 men, age 56 ± 13 years) from the Finnish Cardiovascular Study (FINCAVAS) and a population-based sample of 2683 men (age 53 ± 5.1 years) from the Kuopio Ischaemic Heart Disease study (KIHD). Methods Cox regression was applied for risk prediction with cardiovascular mortality as the primary endpoint. Results In FINCAVAS, during a median 6.3-year (interquartile range (IQR) 4.5–8.2) follow-up period, 180 patients (4.6%) experienced cardiovascular mortality. In KIHD, 562 patients (21.0%) died from cardiovascular causes during the median follow-up of 24.1 (IQR 18.0–26.2) years. The Duke treadmill score was associated with cardiovascular mortality in both populations (FINCAVAS, adjusted hazard ratio (HR) 3.15 for highest vs. lowest Duke treadmill score tertile, 95% confidence interval (CI) 1.83–5.42, P < 0.001; KIHD, adjusted HR 1.71, 95% CI 1.34–2.18, P < 0.001). However, after progressive adjustment for the Duke treadmill score components, the score was not associated with cardiovascular mortality in either study population, as exercise capacity in metabolic equivalents of task was the dominant harbinger of poor prognosis. Conclusions The Duke treadmill score is associated with cardiovascular mortality among patients who have undergone bicycle exercise testing, but metabolic equivalents of task, a component of the Duke treadmill score, proved to be a superior predictor.

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