The effect of hand-hygiene interventions on infectious disease-associated absenteeism in elementary schools: A systematic literature review

Author(s):  
Zhangqi Wang ◽  
Maria Lapinski ◽  
Elizabeth Quilliam ◽  
Lee-Ann Jaykus ◽  
Angela Fraser
2020 ◽  
Vol 7 (9) ◽  
Author(s):  
Takaaki Kobayashi ◽  
Alexandre R Marra ◽  
Marin L Schweizer ◽  
Patrick Ten Eyck ◽  
Chaorong Wu ◽  
...  

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known about the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched 5 databases through February 2020 and performed a meta-analysis of the impact of IDC on the mortality of patients with candidemia. Results A total of 151 patients met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%; P = .002; 23% vs 50%; P = .0022, respectively). A systematic literature review returned 216 reports, of which 13 studies including the present report fulfilled the inclusion criteria. Among the 13 studies with a total of 3582 patients, IDC was performed in 50% of patients. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% vs 47.6%), with a pooled relative risk of 0.41 (95% CI, 0.35–0.49). Ophthalmology referral, echocardiogram, and central line removal were performed more frequently among patients receiving IDC. Conclusions This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with significantly lower mortality and should be considered in all patients with candidemia.


2019 ◽  
Author(s):  
Harmelia Tulak ◽  
Hengki Wijaya ◽  
Susanna Vonny N. Rante ◽  
Nurmadiah ◽  
Helaluddin Helaluddin

Diversity in social life is a sure thing. But in reality, various problems and conflicts have arisen that are caused by intercultural competencies that are not shared by every individual. The concept of intercultural competence is the essential thing today due to several factors, namely globalization, the complexity of social life, and the pace of technological development. Intercultural competence is the ability of each to understand the culture of others and how he can communicate well with people from that culture. This article was developed using the Systematic Literature Review (SLR) method in presenting an intercultural competence learning strategy to students in elementary schools. This article focuses on the intercultural competence learning strategy by integrating technology into class activities as one of the characteristics of learning in the education era 4.0.


Author(s):  
Mohammed A. Alzunitan ◽  
Michael B. Edmond ◽  
Mohammed A. Alsuhaibani ◽  
Riley J. Samuelson ◽  
Marin L. Schweizer ◽  
...  

Abstract Background: Healthcare-associated infections (HAIs) remain a major challenge. Various strategies have been tried to prevent or control HAIs. Positive deviance, a strategy that has been used in the last decade, is based on the observation that a few at-risk individuals follow uncommon, useful practices and that, consequently, they experience better outcomes than their peers who share similar risks. We performed a systematic literature review to measure the impact of positive deviance in controlling HAIs. Methods: A systematic search strategy was used to search PubMed, CINAHL, Scopus, and Embase through May 2020 for studies evaluating positive deviance as a single intervention or as part of an initiative to prevent or control healthcare-associated infections. The risk of bias was evaluated using the Downs and Black score. Results: Of 542 articles potentially eligible for review, 14 articles were included for further analysis. All studies were observational, quasi-experimental (before-and-after intervention) studies. Hand hygiene was the outcome in 8 studies (57%), and an improvement was observed in association with implementation of positive deviance as a single intervention in all of them. Overall HAI rates were measured in 5 studies (36%), and positive deviance was associated with an observed reduction in 4 (80%) of them. Methicillin-resistant Staphylococcus aureus infections were evaluated in 5 studies (36%), and positive deviance containing bundles were successful in all of them. Conclusions: Positive deviance may be an effective strategy to improve hand hygiene and control HAIs. Further studies are needed to confirm this effect.


2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Halma Zahro Mukhlida ◽  
Hilma Hasro Maulida ◽  
Gunanti Khairunnisa ◽  
Margaretha Josephine Mantrono ◽  
Risky Kusuma Hartono ◽  
...  

The infectious disease from  corona virus, or COVID-19, has quickly spread world-wide since 2019. Therapies for managing COVID-19 have yet to be confirmed as medication for the severe sickness that the disease may cause. This study uses PRISMA guidelines as a method for conducting a systematic literature review. We selected relevant studies published from January 2020 to March 2020 by searching Pubmed, Science Direct and Google Scholar. The research focuses on the treatment of and therapies for COVID-19 only to the patients in the hospital. The inclution 8 articles  were screened by using a PRISMA flow after reading 28 abstract  and 28 from whole articles. Sixty-seven articles were collected from several online journal databases, and various therapies were found that are effective in the treatment and management of COVID-19. Clinical improvements and Recovery rate have been achieved in a short time compared to standard care only. The findings of the study show that several therapies are effective in managing the severe illness that can be caused by COVID-19. Nevertheless, research into effective therapies for COVID-19 must be continued to find the best therapy and treatment.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S421-S422
Author(s):  
Takaaki Kobayashi ◽  
Alexandre Marra ◽  
Marin L Schweizer ◽  
Patrick Ten Eyck ◽  
Chaorong Wu ◽  
...  

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known on the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. All patients aged ≥18 years with blood cultures positive for Candida species were included. We only included the first episode of candidemia. Exclusion criteria were death or transfer to the palliative care unit within 48 hours from the time cultures became positive. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched five publication-databases through February 2020 and performed a meta-analysis of the impact of IDC on mortality of patients with candidemia. The study protocol has been submitted to the International Prospective Register for Systematic Reviews (PROSPERO) database (ID 156939) on April 2020. Results A total of 151 patients at our institution met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day, and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%, P = .002; 23% vs 50%, P = .0022, respectively). Our systematic literature review returned 216 reports, of which, 13 studies including ours fulfilled the inclusion criteria. Among the 13 studies with a total 3687 patients, IDC was performed in 49% of patients. Mortality numbers were available in 10 studies. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% and 47.6%) with a pooled relative risk of 0.41 [95% Cl 0.35-0.49]. Ophthalmology referral (61%; 790/1279 and 21%; 273/1304, P < 0.001), echocardiogram (54%; 662/1219 and 28%; 369/1296, P < 0.001), and central line removal (78%; 830/1069 and 61%; 686/1116, P < 0.02) were performed more frequently among patients receiving IDC. Overall mortality Conclusion This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with a lower mortality and should be standard of care in all patients with candidemia. Disclosures Dimitrios Farmakiotis, MD, Astellas (Grant/Research Support) Paul Auwaerter, Collidion (Consultant)DiaSorin (Consultant)Johnson and Johnson (Shareholder)MicroB-Plex (Research Grant or Support)Shionogi (Consultant) Daniel Diekema, bioMerieux, Inc (Grant/Research Support)JMI Laboratories (Consultant)


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