scholarly journals Building resource constraints and feasibility considerations in mathematical models for infectious disease: A systematic literature review

Epidemics ◽  
2021 ◽  
Vol 35 ◽  
pp. 100450
Author(s):  
Fiammetta M. Bozzani ◽  
Anna Vassall ◽  
Gabriela B. Gomez
2020 ◽  
Vol 7 (9) ◽  
Author(s):  
Takaaki Kobayashi ◽  
Alexandre R Marra ◽  
Marin L Schweizer ◽  
Patrick Ten Eyck ◽  
Chaorong Wu ◽  
...  

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known about the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched 5 databases through February 2020 and performed a meta-analysis of the impact of IDC on the mortality of patients with candidemia. Results A total of 151 patients met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%; P = .002; 23% vs 50%; P = .0022, respectively). A systematic literature review returned 216 reports, of which 13 studies including the present report fulfilled the inclusion criteria. Among the 13 studies with a total of 3582 patients, IDC was performed in 50% of patients. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% vs 47.6%), with a pooled relative risk of 0.41 (95% CI, 0.35–0.49). Ophthalmology referral, echocardiogram, and central line removal were performed more frequently among patients receiving IDC. Conclusions This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with significantly lower mortality and should be considered in all patients with candidemia.


Symmetry ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 11
Author(s):  
Ibrahim M. Hezam ◽  
Moddassir k. Nayeem

Humanitarian logistics (HL) is considered one of the most significant issues of disaster operations and management. Thus, HL operation should be viable enough to function well under the uncertain and complex nature of the disaster. Many difficulties in pre-and post-disaster phases bring both human and economic losses. Therefore, it is essential to make sure that the HL operations are designed efficiently. In the last two decades, several publications have emphasized efficient HL operations and proposed several mathematical models and algorithms to increase the efficiency of HL operations and motivated the necessity of a systematic literature review. A systematic literature review is deemed pertinent due to its transparent and detailed article searching procedure. In this study, due to the importance of the mathematical optimization model, we reviewed more than one hundred articles published between 2000 and 2020 to investigate the optimization models in the field of HL. We classified the optimization models into three main problems: facility location problems, relief distribution, and mass evacuation where each of the classified areas includes both deterministic and non-deterministic models.


Author(s):  
Ema Kusen ◽  
Mark Strembeck

Purpose Ever since Mark Weiser coined the term “ubiquitous computing” (ubicomp) in 1988, there has been a general interest in proposing various solutions that would support his vision. However, attacks targeting devices and services of a ubicomp environment have demonstrated not only different privacy issues, but also a risk of endangering user’s life (e.g. by modifying medical sensor readings). Thus, the aim of this paper is to provide a comprehensive overview of security challenges of ubicomp environments and the corresponding countermeasures proposed over the past decade. Design/methodology/approach The results of this paper are based on a literature review method originally used in evidence-based medicine called systematic literature review (SLR), which identifies, filters, classifies and summarizes the findings. Findings Starting from the bibliometric results that clearly show an increasing interest in the topic of ubicomp security worldwide, the findings reveal specific types of attacks and vulnerabilities that have motivated the research over the past decade. This review describes most commonly proposed countermeasures – context-aware access control and authentication mechanisms, cryptographic protocols that account for device’s resource constraints, privacy-preserving mechanisms, and trust mechanisms for wireless ad hoc and sensor networks. Originality/value To the best of our knowledge, this is the first SLR on security challenges in ubicomp. The findings should serve as a reference to an extensive list of scientific contributions, as well as a guiding point for the researchers’ novel to the security research in ubicomp.


2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Halma Zahro Mukhlida ◽  
Hilma Hasro Maulida ◽  
Gunanti Khairunnisa ◽  
Margaretha Josephine Mantrono ◽  
Risky Kusuma Hartono ◽  
...  

The infectious disease from  corona virus, or COVID-19, has quickly spread world-wide since 2019. Therapies for managing COVID-19 have yet to be confirmed as medication for the severe sickness that the disease may cause. This study uses PRISMA guidelines as a method for conducting a systematic literature review. We selected relevant studies published from January 2020 to March 2020 by searching Pubmed, Science Direct and Google Scholar. The research focuses on the treatment of and therapies for COVID-19 only to the patients in the hospital. The inclution 8 articles  were screened by using a PRISMA flow after reading 28 abstract  and 28 from whole articles. Sixty-seven articles were collected from several online journal databases, and various therapies were found that are effective in the treatment and management of COVID-19. Clinical improvements and Recovery rate have been achieved in a short time compared to standard care only. The findings of the study show that several therapies are effective in managing the severe illness that can be caused by COVID-19. Nevertheless, research into effective therapies for COVID-19 must be continued to find the best therapy and treatment.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S421-S422
Author(s):  
Takaaki Kobayashi ◽  
Alexandre Marra ◽  
Marin L Schweizer ◽  
Patrick Ten Eyck ◽  
Chaorong Wu ◽  
...  

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known on the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. All patients aged ≥18 years with blood cultures positive for Candida species were included. We only included the first episode of candidemia. Exclusion criteria were death or transfer to the palliative care unit within 48 hours from the time cultures became positive. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched five publication-databases through February 2020 and performed a meta-analysis of the impact of IDC on mortality of patients with candidemia. The study protocol has been submitted to the International Prospective Register for Systematic Reviews (PROSPERO) database (ID 156939) on April 2020. Results A total of 151 patients at our institution met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day, and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%, P = .002; 23% vs 50%, P = .0022, respectively). Our systematic literature review returned 216 reports, of which, 13 studies including ours fulfilled the inclusion criteria. Among the 13 studies with a total 3687 patients, IDC was performed in 49% of patients. Mortality numbers were available in 10 studies. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% and 47.6%) with a pooled relative risk of 0.41 [95% Cl 0.35-0.49]. Ophthalmology referral (61%; 790/1279 and 21%; 273/1304, P < 0.001), echocardiogram (54%; 662/1219 and 28%; 369/1296, P < 0.001), and central line removal (78%; 830/1069 and 61%; 686/1116, P < 0.02) were performed more frequently among patients receiving IDC. Overall mortality Conclusion This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with a lower mortality and should be standard of care in all patients with candidemia. Disclosures Dimitrios Farmakiotis, MD, Astellas (Grant/Research Support) Paul Auwaerter, Collidion (Consultant)DiaSorin (Consultant)Johnson and Johnson (Shareholder)MicroB-Plex (Research Grant or Support)Shionogi (Consultant) Daniel Diekema, bioMerieux, Inc (Grant/Research Support)JMI Laboratories (Consultant)


2016 ◽  
Vol 2016 ◽  
pp. 1-20 ◽  
Author(s):  
Muhammad Salman Habib ◽  
Young Hae Lee ◽  
Muhammad Saad Memon

In the past decade the humanitarian supply chain (HSC) has attracted the attention of researchers due to the increasing frequency of disasters. The uncertainty in time, location, and severity of disaster during predisaster phase and poor conditions of available infrastructure during postdisaster phase make HSC operations difficult to handle. In order to overcome the difficulties during these phases, we need to assure that HSC operations are designed in an efficient manner to minimize human and economic losses. In the recent times, several mathematical optimization techniques and algorithms have been developed to increase the efficiency of HSC operations. These techniques and algorithms developed for the field of HSC motivate the need of a systematic literature review. Owing to the importance of mathematical modelling techniques, this paper presents the review of the mathematical contributions made in the last decade in the field of HSC. A systematic literature review methodology is used for this paper due to its transparent procedure. There are two objectives of this study: the first one is to conduct an up-to-date survey of mathematical models developed in HSC area and the second one is to highlight the potential research areas which require attention of the researchers.


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