scholarly journals 354: Does maternal anemia impact fetal oxygenation and risk of acidemia at term?

2020 ◽  
Vol 222 (1) ◽  
pp. S236-S237
Author(s):  
Virginia Watkins ◽  
Antonina I. Frolova ◽  
Ebony B. Carter ◽  
Molly J. Stout ◽  
George A. Macones ◽  
...  
Keyword(s):  
Maternal Anemia ◽  
Fetal Oxygenation

Complex and irregular heart rate dynamics in fetuses compromised by maternal anemia as a high-risk pregnancy

2015 ◽  
Vol 43 (6) ◽  
Author(s):  
Young-Sun Park ◽  
Jeong-Kyu Hoh
Keyword(s):  
Heart Rate ◽  
High Risk ◽  
Approximate Entropy ◽  
Risk Groups ◽  
Adverse Outcomes ◽  
Maternal Anemia ◽  
Risk Pregnancy ◽  
Heart Rate Dynamics ◽  
Study Population ◽  
Normal Controls

AbstractTo examine how complex and irregular fetal heart rate (FHR) dynamics differ between fetuses of normal pregnancies and those of pregnancies complicated by maternal anemia (MA), and to place this in the context of high-risk pregnancies.Our study population consisted of 97 pregnant women affected by MA, 118 affected by pregnancy-induced hypertension (PIH), 88 affected by gestational diabetes mellitus (GDM), 53 with preterm premature rupture of membranes (pPROM), and 356 normal pregnancies as controls. We calculated approximate entropy (ApEn), sample entropy (SampEn), and correlation dimension (CD) to quantify irregularity and the chaotic dynamics of each FHR time series.The ApEn in the fetuses of the MA and PIH groups was significantly lower than that of the normal controls (P<0.05). The SampEn was significantly lower in the high-risk groups, except for the pPROM group, than in the normal controls (P<0.05). The CD in the PIH and severe MA groups was significantly lower than that of the normal controls (P<0.05, respectively). In the MA group, the dynamic indices showed a highly significant positive correlation with hemoglobin (Hb) levels (P<0.0001).The decreased complexity and/or irregularity in the FHR from pregnancies with MA may reflect abnormalities in the complex, integrated cardiovascular control. The irregularity and complexity of the FHR increased together with Hb levels in pregnancies with MA. Our data suggest that the integrity of the nervous system in the fetuses compromised by severe MA might result directly in adverse outcomes.

A DOUBLE BLIND COMPARATIVE STUDY BETWEEN INTRATHECAL BUPIVACAINE AND INTRATHECAL FENTANYLAS THE INITIAL DOSE OF COMBINED SPINAL EPIDURAL TECHNIQUE FOR LABOUR ANALGESIA

2021 ◽  
pp. 48-50
Author(s):  
Niraj Kumar Mishra ◽  
Sushil Kumar
Keyword(s):  
Side Effects ◽  
Fetal Distress ◽  
Labour Pain ◽  
Sampling Procedure ◽  
Chi Square ◽  
Double Blind ◽  
Motor Weakness ◽  
Group I ◽  
Group Ii ◽  
Fetal Oxygenation

Introduction: Labour pain is among the most severe pain a woman can experience in her lifetime. Painful labour has decrimental effects on both mother and fetus leads to severe physical and psychological stress. Maternal hyperventilation in response to pain reduces fetal oxygenation and hypoventilation between contractions combined with decreased blood ow worsens fetal hypoxemia. It has been suggested that conning women to bed during labour may cause the labour to be longer and more painful with increase in abnormal presentation, instrumental deliveries and fetal distress. Aims And Objectives:The onset, quality and duration of their analgesic action. Incidence of unwanted effects like muscle weakness, hypotension, pruritus, nausea/vomiting, fetal bradycardia by the individual drugs. Materials And Methods: The study was conducted in the department of anesthesia, Darbhanga Medical College & Hospital, Laheriasarai, Bihar. Methods of collection of data (including sampling procedure if any) : After institutional committee approval and written informed consent from parturients and their relatives for the procedure the study was conducted and data were collected. Results: Duration of analgesia was found varying widely. It was 55±12.34 minutes in Group I whereas 75 ±14.36 minutes in Group II. The incidence of pruritus almost mild or negligible in both groups. The incidence of motor weakness in group II was 24 (80%) whereas in group I it was 10(33%). There was signicant statistics difference in motor weakness between two groups (p< 0.001) by Chi square test 9 with yate's correction. Other side effects differences between two groups were not statistically signicant. Summary And Conclusion:Both the drugs provided excellent quality of analgesia to the parturient in pain. The difference in duration of analgesia was signicant between the two groups statistically. Mean duration of analgesia lasted for 55 minutes in group I whereas in group II, it lasted for 75 minutes. Main side effects encountered in this study were motor weakness of longer duration in group II than in group I. Other side effects like nausea-vomiting were comparable to each other and were minimal in nature.

scholarly journals Influence of Maternal Anemia During Pregnancy on Placenta and Newborns

2014 ◽  
Vol 68 (3) ◽  
pp. 184 ◽  
Author(s):  
Melisa Lelic ◽  
Gordana Bogdanovic ◽  
Suada Ramic ◽  
Elvira Brkicevic
Keyword(s):  
Maternal Anemia ◽  
Anemia During Pregnancy

scholarly journals No sympathy for the hypoxic: the role of fetal oxygenation in autonomic dysfunction

2018 ◽  
Vol 596 (23) ◽  
pp. 5507-5508 ◽  
Author(s):  
Jonathan D. Hoang ◽  
Marmar Vaseghi
Keyword(s):  
Autonomic Dysfunction ◽  
Fetal Oxygenation

Maternal-Fetal Oxygenation

2018 ◽  
pp. 175-182
Author(s):  
Alfred D. Fleming ◽  
Marsha Henn
Keyword(s):  
Fetal Oxygenation

scholarly journals Breath of Life: Heart Disease Link to Developmental Hypoxia

Circulation ◽  
2021 ◽  
Vol 144 (17) ◽  
pp. 1429-1443
Author(s):  
Dino A. Giussani
Keyword(s):  
Heart Disease ◽  
Maternal Obesity ◽  
Clinical Intervention ◽  
Fetal Hypoxia ◽  
Long Term Effects ◽  
Lifestyle Risk Factors ◽  
Sustained Reduction ◽  
Short And Long Term ◽  
Lifestyle Risk ◽  
Fetal Oxygenation

Heart disease remains one of the greatest killers. In addition to genetics and traditional lifestyle risk factors, we now understand that adverse conditions during pregnancy can also increase susceptibility to cardiovascular disease in the offspring. Therefore, the mechanisms by which this occurs and possible preventative therapies are of significant contemporary interest to the cardiovascular community. A common suboptimal pregnancy condition is a sustained reduction in fetal oxygenation. Chronic fetal hypoxia results from any pregnancy with increased placental vascular resistance, such as in preeclampsia, placental infection, or maternal obesity. Chronic fetal hypoxia may also arise during pregnancy at high altitude or because of maternal respiratory disease. This article reviews the short- and long-term effects of hypoxia on the fetal cardiovascular system, and the importance of chronic fetal hypoxia in triggering a developmental origin of future heart disease in the adult progeny. The work summarizes evidence derived from human studies as well as from rodent, avian, and ovine models. There is a focus on the discovery of the molecular link between prenatal hypoxia, oxidative stress, and increased cardiovascular risk in adult offspring. Discussion of mitochondria-targeted antioxidant therapy offers potential targets for clinical intervention in human pregnancy complicated by chronic fetal hypoxia.

scholarly journals The effect of maternal oxygen inhalation upon fetal oxygenation

1968 ◽  
Vol 47 (3) ◽  
pp. 548-555 ◽  
Author(s):  
Frederick C. Battaglia ◽  
Giacomo Meschia ◽  
Edgar L. Makowski ◽  
Watson Bowes
Keyword(s):  
Oxygen Inhalation ◽  
Fetal Oxygenation

Anesthesia in a Pregnant Patient Presenting for Urgent Nonobstetric Surgery

2018 ◽  
pp. 243-248
Author(s):  
Shobana Bharadwaj ◽  
Jessica Galey
Keyword(s):  
Preterm Labor ◽  
Anesthetic Management ◽  
Pregnant Patient ◽  
Quadrant Pain ◽  
Reversal Agents ◽  
Fetal Safety ◽  
Fetal Oxygenation

For obstetric patients undergoing nonobstetric surgeries, the anesthesiologist has to take into consideration both maternal and fetal safety during the pre-, intra-, and postoperative periods. The goal of the anesthetic management should be to apply maternal physiologic changes, avoid teratogenic agents, avoid decreased uteroplacental perfusion and/or fetal oxygenation, and prevent preterm labor. Decisions on the timing of the procedure and intraoperative fetal and uterine monitoring must be multidisciplinary. The chapter uses a case study of a 24-year-old woman who is admitted at 33 weeks gestation with nausea, vomiting, and right upper quadrant pain. Topics covered include teratogenicity, uteroplacental perfusion, and reversal agents.

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