Low normal glucose tolerance test as a predictor of small for gestational age infants

A comparison was made between the results of a standard 75 g oral glucose tolerance test and total haemoglobin A1 in 168 subjects referred by their general practitioners for the diagnosis of diabetes mellitus. The subjects were classified as having normal, impaired or diabetic glucose tolerance using WHO criteria. Of 108 subjects with normal glucose tolerance only three had haemoglobin A1 concentrations over 8%. Of 10 with impaired glucose tolerance two had haemoglobin A1 concentrations over 8%. Of 47 with diabetic responses, eight had haemoglobin A1 concentrations below 9%. There was a significant difference between the haemoglobin A1 concentration when fasting and that 2 hours after the glucose load in the subjects with a diabetic glucose tolerance response, but no significant difference between the two values in the other subjects.

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528: Insulin resistance during midpregnancy is associated with maternal weight gain throughout pregnancy in non-obese women with normal glucose tolerance test

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2016.11.263 ◽

2017 ◽

Vol 216 (1) ◽

pp. S312

Author(s):

Ichiro Yasuhi ◽

Hiroshi Yamashita ◽

Sachie Suga ◽

Misao Fukuoka ◽

Megumi Koga ◽

...

Keyword(s):

Insulin Resistance ◽

Weight Gain ◽

Glucose Tolerance ◽

Glucose Tolerance Test ◽

Tolerance Test ◽

Normal Glucose Tolerance ◽

Maternal Weight Gain ◽

Obese Women ◽

Maternal Weight ◽

Normal Glucose

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Individuation of different metabolic phenotypes in normal glucose tolerance test

Acta Diabetologica ◽

10.1007/s00592-009-0165-9 ◽

2009 ◽

Vol 47 (2) ◽

pp. 167-172 ◽

Cited By ~ 5

Author(s):

G. P. Carnevale Schianca ◽

E. Colli ◽

S. Onolfo ◽

R. Pedrazzoli ◽

G. P. Fra ◽

...

Keyword(s):

Glucose Tolerance ◽

Glucose Tolerance Test ◽

Tolerance Test ◽

Normal Glucose Tolerance ◽

Metabolic Phenotypes ◽

Normal Glucose

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Body surface area may explain sex differences in findings from the oral glucose tolerance test among subjects with normal glucose tolerance

Nutrition Metabolism and Cardiovascular Diseases ◽

10.1016/j.numecd.2021.05.018 ◽

2021 ◽

Author(s):

Samuel Palmu ◽

Susanna Kuneinen ◽

Hannu Kautiainen ◽

Johan G. Eriksson ◽

Päivi E. Korhonen

Keyword(s):

Sex Differences ◽

Glucose Tolerance ◽

Oral Glucose Tolerance Test ◽

Body Surface ◽

Glucose Tolerance Test ◽

Tolerance Test ◽

Normal Glucose Tolerance ◽

Oral Glucose ◽

Oral Glucose Tolerance ◽

Normal Glucose

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A case–control study to predict the risk of gestational diabetes mellitus by initial fasting blood sugar or past gestational history

International Journal of Reproductive BioMedicine ◽

10.18502/ijrm.v19i4.9064 ◽

2021 ◽

Author(s):

Tahmineh Ezazi Bojnordi ◽

Sedigheh Hantoushzadeh ◽

Masomeh Sabzevary ◽

Zahra Heidari

Keyword(s):

Diabetes Mellitus ◽

Glucose Tolerance ◽

Glucose Tolerance Test ◽

First Trimester ◽

Tolerance Test ◽

Normal Glucose Tolerance ◽

Third Trimester ◽

Previous Pregnancy ◽

Normal Glucose ◽

History Of

Background: Gestational diabetes mellitus (GDM) deserves proper prevention, diagnosis, and management due to healthcare implications from both maternal and fetal concerns. Objective: To evaluate the rate and investigate the risk factors for developing GDM. Materials and Methods: In this case-control, universal screening for GDM between 24 and 28 wk of gestation was performed in 613 pregnant women attending a prenatal clinic in Tehran who were followed-up until delivery between March 2017 to March 2018. Of the 613 women, 143 had GDM and 470 had normal glucose tolerance test as the primary diagnosis. Some GDM risk factors were compared in two groups. Results: Impaired glucose tolerance test was detected in 143 (23.3%) patients. Prevalence of GDM was higher in the first-trimester fasting blood sugar (FBS) > 90 qmg/dl group (p < 0.001). Comparison of the GDM and the normal glucose tolerance test groups demonstrated significant differences in maternal age, first-trimester FBS, third-trimester vitamin D level, maternal platelet count, maternal body mass index (BMI) (before 12 wk of gestation), weight gain during pregnancy, and the history of gestational complications in previous pregnancy (p < 0.01). In logistic regression, GDM was independently associated with older maternal age, higher first-trimester FBS, the history of gestational complications in previous pregnancy, lower third-trimester vitamin D level, and higher maternal platelet count (p < 0.01). Conclusion: Both patients with higher initial FBS and the history of gestational complications in previous pregnancy should be considered high risk for GDM and screened earlier. Key words: Diabetes Mellitus, Gestational, Blood glucose, Risk factor.

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The Relationship Between 1 Hour Glycemia, During Oral Glucose Tolerance Test and Cardiometabolic Risk

Romanian Journal of Diabetes Nutrition and Metabolic Diseases ◽

10.2478/v10255-012-0004-6 ◽

2012 ◽

Vol 19 (1) ◽

pp. 25-31

Author(s):

Oana Albai ◽

Romulus Timar

Keyword(s):

Diabetes Mellitus ◽

Glucose Tolerance ◽

Cardiometabolic Risk ◽

Glucose Tolerance Test ◽

Normal Values ◽

Tolerance Test ◽

Normal Glucose Tolerance ◽

Oral Glucose ◽

Normal Glucose ◽

The Relationship

The Relationship Between 1 Hour Glycemia, During Oral Glucose Tolerance Test and Cardiometabolic RiskBackground Diabetes mellitus is a very common disease, worldwide there are currently over 366 million diabetics. It seems that people with normal glucose tolerance and blood glucose at 1 hour during OGTT ≥200mg% represent an intermediate phenotype of abnormal glucose metabolism, another disturbance of carbohydrate metabolism that is associated with increased cardiometabolic risk. Objectives Starting from these premises, we decided to analyze the subjects with glucose at 1 hour during OGTT ≥200mg%, but with normal values for fasting glucose and 2 hours glucose. In this subgroup of subjects some parameters of CMR were analyzed. We also performed a comparison of this subgroup of subjects with both normal glucose tolerance and 1-hour glucose <200mg%, and with those with abnormal glucose tolerance. Results According to currently used recommendations to diagnose diabetes mellitus, from the 778 people included in this study, 167 (21.5%) had disturbances of carbohydrate metabolism, being classified as patoglycemic and 611 persons (78.5%) had normal values of fasting glucose and 2 hours glucose during OGTT, being considered normoglycemic. From the 611 people who were classified as normal glucose tolerance, based on the currently used criteria for diagnosis of diabetes mellitus, a total of 44 persons (7.2%) had, however, the value of 1-hour glucose during OGTT ≥200mg%, which represents 5.6% of the entire group studied. Conclusions Patients with normal glucose tolerance and glucose ≥200mg% at 1 hour during OGTT represent a new subgroup of impaired glucose tolerance, which requires strict lifestyle advice and possibly pharmacological measures to prevent or delay progression to abnormal glucose tolerance.

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