Risk drinking behavior among psychotropic drug users in an aging Finnish population: The FinDrink study

Abstract Introduction The prevalence of psychotropic drug use in our society is increasing especially in older adults, thereby provoking severe adverse drug reactions (ADR). To identify specific patient risk profiles associated with psychotropic drug use in the situation of polymedication. Methods Cases of ADRs in general emergency departments (ED) collected within the multi-center prospective observational study (ADRED) were analyzed (n=2215). We compared cases with use of psychotropic drugs and without concerning their clinical presentation at the ED. Results A third of patients (n=731, 33%) presenting to the ED with an ADR took at least 1 psychotropic drug. Patients with psychotropic drug use tended to be older, more often female, and took a higher number of drugs (all p<0.001). The frequency of falls was almost 3 times higher than compared to the non-psychotropic drug group (10.5 vs. 3.9%, p<0.001), and similar syncope was also more often seen in the psychotropic drug users (8.8 vs. 5.5%, p=0.004). The use of psychotropic drugs increased the risk for falls by a factor of 2.82 (OR, 95% CI (1.90–4.18)), when adjusting for gender, age, numbers of pre-existing diseases, and drugs, respectively. Discussion The association of psychotropic drug use with fall and syncope in combination with polymedication and older age leads to the suspicion that psychotropic drugs might be potentially harmful in specific risk populations such as older adults. It may lead us to thoroughly weigh the benefit against risk in a patient-oriented way, leading to an integrative personalized therapy approach.

Download Full-text

Treatment of Mental Problems in General Practice

Scandinavian Journal of Social Medicine ◽

10.1177/140349488701500303 ◽

1987 ◽

Vol 15 (3) ◽

pp. 131-137 ◽

Cited By ~ 3

Author(s):

Gunnar Tellnes ◽

Arild Bjørndal ◽

Per Fugelli

Keyword(s):

General Practice ◽

Psychotropic Drug ◽

Psychotropic Drugs ◽

Drug Users ◽

Local Community ◽

Treatment And Prevention ◽

Defined Daily Doses ◽

Mental Problems ◽

One Year ◽

Chronic Use

The aim of the study was to provide a basis for improving the treatment and prevention of mental problems in a defined local community. The prescribing of psychotropic drugs has been recorded as well as the use of non-drug therapy and the factors which worsened the patients' mental problems. The rate of psychotropic drug-users was 15% for females and 9% for males. The total prescribing during one year amounted to 59 defined daily doses (DDD) per thousand inhabitants per day. Hypnotics/sedatives constituted 30%, anti-histamines 23%, neuroleptics 18%, minor tranquillizers 16%, and antidepressants 13%. About 1/4 of the psychotropic drug-users was prescribed more than 180 DDD per year, representing a risk group for chronic use. The majority of all psychotropic drugs (65%) was prescribed through indirect contacts implying a danger of developing “repeat prescription syndromes”. Less than one half of the patients who might have benefited from referral to a psychiatrist had, in fact, been referred during the previous three years. Somatic disease (among the psychotropic drug-users) and illness among other family members were frequently reported as worsening factors. This indicates the importance of holistic therapy and prophylaxis in general practice. Among our advice for prevention of mental problems to the local authorities was the arrangement of weekly social meetings and clubs for disabled pensioners and elderly people.

Download Full-text

Insights Into Adolescents' Substance Use in a Low–Middle-Income Country During the COVID-19 Pandemic

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.739698 ◽

2021 ◽

Vol 12 ◽

Author(s):

Lee Thung Sen ◽

Kristiana Siste ◽

Enjeline Hanafi ◽

Belinda Julivia Murtani ◽

Hans Christian ◽

...

Keyword(s):

Substance Use ◽

Alcohol Use ◽

Cigarette Smoking ◽

Prosocial Behavior ◽

Drug Users ◽

Online Survey ◽

Drinking Behavior ◽

Middle Income ◽

Adolescent Alcohol Use ◽

Adolescent Alcohol

Introduction: The COVID-19 pandemic and its lockdown have been a significant life event for many individuals, particularly adolescents. The immense psychological pressure could drive risky behavior, e.g., substance use, while lockdown might lead to decreased use. This study aimed to observe the change in substance use among adolescents in Indonesia and the moderating variables to consumption during the COVID-19 lockdown period.Methods: This study utilized an online survey from April 28, 2020 to June 30, 2020. The hyperlink was disseminated to school administrators and parenting groups through social media and direct messages. A total of 2,932 adolescents (17.4 ± 2.24 and 78.7% females) submitted valid responses. The survey was comprised of a sociodemographic section, substance use details, and psychometric sections, including the Alcohol Use Disorders Identification Test (AUDIT), Cigarette Dependence Scale 12 (CDS-12), Pittsburgh Sleep Quality Index (PSQI), and Strength and Difficulties Questionnaire (SDQ).Results: Overall, adolescent alcohol use during the pandemic was 5.1%, cigarette smoking was 3.1%, and drug consumption was 0.4%. Over half (53.4%) of alcohol drinkers reported increased drinking, and 33.1% had harmful or dependence-like drinking behavior; in contrast, 44.4% of adolescent smokers disclosed reduced cigarette consumption. Around 37.8% of the drug users indicated increased use. During the pandemic, adolescent alcohol use was associated with higher education [adjusted odds ratio (AOR) = 2.67, 95% confidence interval (CI) 1.02–4.86, p = 0.04], higher AUDIT scores (AOR = 1.33, 95% CI 1.25–1.42, p < 0.001), and very low prosocial behavior (AOR = 2.46, 95% CI 1.52–3.88, p < 0.001). Cigarette smoking was correlated with male sex (AOR = 9.56, 95% CI 5.64–16.62, p < 0.001), age (AOR = 1.40, 95% CI 1.14–1.75, p < 0.001), and higher CDS score (AOR = 1.17, 95% CI 1.13–1.20, p < 0.001).Conclusions: Rates of adolescent substance use were significant, with sizeable proportions reporting higher usage. This appeared to occur predominantly in specific demographics and those with a lower protective psychosocial attribute, i.e., prosocial behavior, during the lockdown. These findings should urge the strengthening of adolescent addiction care during and after the pandemic.

Download Full-text

Assessment of Gut Bacteria Profile and Antibiotic Resistance Pattern Among Psychotropic Drug Users: Comparative Cross-Sectional Study

Infection and Drug Resistance ◽

10.2147/idr.s305992 ◽

2021 ◽

Vol Volume 14 ◽

pp. 1875-1881

Author(s):

Mulatu Gashaw ◽

Zufan Hailu Marame ◽

Mubarek Abera ◽

Solomon Ali

Keyword(s):

Antibiotic Resistance ◽

Psychotropic Drug ◽

Drug Users ◽

Cross Sectional Study ◽

Gut Bacteria ◽

Resistance Pattern ◽

Sectional Study ◽

Cross Sectional ◽

Antibiotic Resistance Pattern

Download Full-text

Les psychotropes et le vieillissement normal: une perspective psychosociale et socio-économique

Canadian Journal on Aging / La Revue canadienne du vieillissement ◽

10.1017/s0714980800009429 ◽

1996 ◽

Vol 15 (4) ◽

pp. 559-582 ◽

Cited By ~ 8

Author(s):

Guilhème Pérodeau ◽

Adèle Jomphe Hill ◽

Lisette Hay-Paquin ◽

Élise Amyot

Keyword(s):

Problem Solving ◽

Psychotropic Drug ◽

Drug Users ◽

Economic Status ◽

Clinical Intervention ◽

Community Dwelling ◽

Daily Hassles ◽

Monthly Basis ◽

Face To Face ◽

Chronic Stressor

ABSTRACTThe goal of this study was to examine the reaction (anxiety, depression, and helplessness) and adaptive strategies (problem-solving and emotion-reducing) of community-dwelling elderly, confronted by one specific chronic stressor. We have conducted three face-to-face home interviews on a monthly basis with a follow-up interview seven months later. There were 237 psychotropic drug users and non-users, of high or low socio-economic status. Not only were low socio-economic psychotropic drug users more anxious about the targeted hassle of the week, but they also relied on and used more problem-solving strategies than non-drug users. It is suggested that psychotropic drug use be looked at as a strategy like any others rather than as passive behaviour when facing daily hassles. Moreover, using a high number of coping strategies is not synonymous with being good at coping with chronic stress. Various recommandations for clinical intervention are put forward.

Download Full-text

Perfil de usuários de psicofármacos atendidos em uma farmácia comunitária do alto sertão paraibano

Revista Brasileira de Educação e Saúde ◽

10.18378/rebes.v6i1.3931 ◽

2016 ◽

Vol 6 (1) ◽

pp. 01

Author(s):

Nathalia Minelli Medeiros de Sousa ◽

Natália Bitú Pinto ◽

Francileuda Batista de Almeida ◽

Neurislene Da Silva Maciel ◽

Symara Abrantes Albuquerque de Oliveira Cabral ◽

...

Keyword(s):

Drug Interactions ◽

Community Pharmacy ◽

Psychotropic Drug ◽

Psychotropic Drugs ◽

Drug Users ◽

Public Health Problem ◽

Structured Interview ◽

Adherence To Treatment ◽

One Year ◽

The City

O estudo teve o objetivo de identificar o perfil dos usuários de psicofármacos atendidos em uma farmácia comunitária no município de Cajazeiras - PB. A pesquisa é do tipo exploratória descritiva, com abordagem quantitativa. A coleta de dados foi realizada em agosto a outubro de 2011, com uma entrevista estruturada aplicada a uma amostra de140 clientes. Os resultados mostram que 79% da população estudada foram mulheres, apresentando idade entre 40 e 49 anos. O Clonazepam foi o medicamento mais consumido; 40% utilizavam a mais de um ano; 94% relataram ter tido melhoras no seu quadro clínico após o uso; 42% afirmaram usar esse medicamento para tratamento de insônia; 52% responderam que fazem uso de outros medicamentos concomitantemente ao tratamento com psicofármacos, o que é um dado importante devido às interações medicamentosas. Assim, esta havendo um aumento da incidência de transtornos psiquiátricos, o que é um problema de saúde pública, gerando um impacto social e econômico. Dessa forma, é importante que o farmacêutico oriente os pacientes com relação ao uso de psicofármacos, a fim de evitar efeitos tóxicos e interações medicamentosas, e buscando aumentar a eficácia do tratamento e reduzindo a falta de adesão ao tratamento.Profile of psychotropic drug users treated in a Community Pharmacy of Upper Paraíba backwoods<pre>ABSTRACT:. The study aimed to identify the profile of psychotropic drug users seen at a community pharmacy in the city of Cajazeiras - PB. The research is descriptive exploratory with a quantitative approach. Data collection was conducted in August-October 2011, with a structured interview applied to a sample of 140 customers. The results show that 79% of the population were women, with ages ranging from 40 to 49 years. The Clonazepam was the most consumed drug; 40% used for more than one year; 94% reported having had improvements in their clinical condition after use; 42% said they use this medication to treat insomnia; 52% answered that they use other drugs concomitantly to treatment with psychotropic drugs, which is an important data due to drug interactions. Thus, this having an increased incidence of psychiatric disorders, which is a public health problem, generating a social and economic impact. Thus, it is important that the east pharmacist patients regarding the use of psychotropic drugs in order to avoid toxic effects and drug interactions, and seeking to increase the effectiveness of treatment and reduce the lack of adherence to treatment.</pre>

Download Full-text