Temperature-responsive grafted polymer brushes obtained from renewable sources with potential application as substrates for tissue engineering

2017 ◽  
Vol 407 ◽  
pp. 546-554 ◽  
Author(s):  
Joanna Raczkowska ◽  
Yurij Stetsyshyn ◽  
Kamil Awsiuk ◽  
Małgorzata Lekka ◽  
Monika Marzec ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Potential Application ◽  
Polymer Brushes ◽  
Renewable Sources ◽  
Grafted Polymer ◽  
Temperature Responsive

Glass transition in temperature-responsive poly(butyl methacrylate) grafted polymer brushes. Impact of thickness and temperature on wetting, morphology, and cell growth

2018 ◽  
Vol 6 (11) ◽  
pp. 1613-1621 ◽  
Author(s):  
Yurij Stetsyshyn ◽  
Joanna Raczkowska ◽  
Ostap Lishchynskyi ◽  
Kamil Awsiuk ◽  
Joanna Zemla ◽  
...  
Keyword(s):  
Glass Transition ◽  
Cell Growth ◽  
Polymer Brushes ◽  
Butyl Methacrylate ◽  
Grafted Polymer ◽  
Temperature Responsive ◽  
Biocompatible Coating

PBMA as temperature-responsive and biocompatible coating.

Shape-Controlled synthesis of silver nanoparticles in temperature-responsive grafted polymer brushes for optical applications

2019 ◽  
Vol 463 ◽  
pp. 1124-1133 ◽  
Author(s):  
Yurij Stetsyshyn ◽  
Kamil Awsiuk ◽  
Viktor Kusnezh ◽  
Joanna Raczkowska ◽  
Benedykt R. Jany ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Polymer Brushes ◽  
Controlled Synthesis ◽  
Grafted Polymer ◽  
Temperature Responsive ◽  
Shape Controlled ◽  
Optical Applications

scholarly journals Fabrication and Impact of Fouling-Reducing Temperature-Responsive POEGMA Coatings with Embedded CaCO3 Nanoparticles on Different Cell Lines

Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1417
Author(s):  
Ostap Lishchynskyi ◽  
Yurij Stetsyshyn ◽  
Joanna Raczkowska ◽  
Kamil Awsiuk ◽  
Barbara Orzechowska ◽  
...  
Keyword(s):  
Polymer Brushes ◽  
Biologically Active ◽  
Temperature Dependent ◽  
Grafted Polymer ◽  
Caco3 Nanoparticles ◽  
Temperature Responsive ◽  
Active Substrate ◽  
Induced Changes ◽  
Glycol Methyl Ether ◽  
Active Substances

In the present work, we have successfully prepared and characterized novel nanocomposite material exhibiting temperature-dependent surface wettability changes, based on grafted brush coatings of non-fouling poly(di(ethylene glycol)methyl ether methacrylate) (POEGMA) with the embedded CaCO3 nanoparticles. Grafted polymer brushes attached to the glass surface were prepared in a three-step process using atom transfer radical polymerization (ATRP). Subsequently, uniform CaCO3 nanoparticles (NPs) embedded in POEGMA-grafted brush coatings were synthesized using biomineralized precipitation from solutions of CaCl2 and Na2CO3. An impact of the low concentration of the embedded CaCO3 NPs on cell adhesion and growth depends strongly on the type of studied cell line: keratinocytes (HaCaT), melanoma (WM35) and osteoblastic (MC3T3-e1). Based on the temperature-responsive properties of grafted brush coatings and CaCO3 NPs acting as biologically active substrate, we hope that our research will lead to a new platform for tissue engineering with modified growth of the cells due to the release of biologically active substances from CaCO3 NPs and the ability to detach the cells in a controlled manner using temperature-induced changes of the brush.

scholarly journals Binary Biocompatible CNC–Gelatine Hydrogel as 3D Scaffolds Suitable for Cell Culture Adhesion and Growth

Applied Nano ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 118-127
Author(s):  
Luca Zoia ◽  
Anna Binda ◽  
Laura Cipolla ◽  
Ilaria Rivolta ◽  
Barbara La Ferla
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Cell Cultures ◽  
Cellulose Nanocrystals ◽  
Potential Application ◽  
Chemical Properties ◽  
Cellular Adhesion ◽  
Chemical Crosslinking ◽  
3D Scaffolds ◽  
Physical Chemical

Binary nano-biocomposite 3D scaffolds of cellulose nanocrystals (CNCs)—gelatine were fabricated without using chemical crosslinking additives. Controlled oxidative treatment allowed introducing carboxyl or carbonyl functionalities on the surface of CNCs responsible for the crosslinking of gelatine polymers. The obtained composites were characterized for their physical-chemical properties. Their biocompatibility towards different cell cultures was evaluated through MTT and LDH assays, cellular adhesion and proliferation experiments. Gelatine composites reinforced with carbonyl-modified CNCs showed the most performing swelling/degradation profile and the most promising adhesion and proliferation properties towards cell lines, suggesting their potential application in the field of tissue engineering.

Electrospun Functionalized Polyaniline Copolymer-Based Nanofibers with Potential Application in Tissue Engineering

2010 ◽  
Vol 10 (12) ◽  
pp. 1424-1431 ◽  
Author(s):  
Marija Gizdavic-Nikolaidis ◽  
Sudip Ray ◽  
Jared R. Bennett ◽  
Allan J. Easteal ◽  
Ralph P. Cooney
Keyword(s):  
Tissue Engineering ◽  
Potential Application
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