Activities of daily living function and neuropsychiatric symptoms of people with dementia and caregiver burden: The mediating role of caregiving hours

2019 ◽  
Vol 81 ◽  
pp. 25-30 ◽  
Author(s):  
Chung-Ying Lin ◽  
Pei-Yu Shih ◽  
Li-Jung Elizabeth Ku
2017 ◽  
Vol 13 (7S_Part_10) ◽  
pp. P540-P540
Author(s):  
Hanne Marie Rostad ◽  
Martine Puts ◽  
Milada Cvancarova Småstuen ◽  
Inger Utne ◽  
Ellen Karine Grov ◽  
...  

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 485-485
Author(s):  
Kent Jason Cheng ◽  
Darcy McMaughan ◽  
Matthew Smith

Abstract Limitations on activities of daily living (ADL) and instrumental activities of daily living (IADL) can be deleterious to an older person’s life satisfaction and overall feelings of wellbeing. This study explored the possible mediating role of optimism on relationship between changes in ADL/IADL and life satisfaction over time. Using 2006-2016 data from the Health and Retirement Study (n=11,869), growth curve modelling was used to account for intra-individual and inter-individual changes in life satisfaction trajectories. All models controlled for age, sex, marital status, years of education, self-rated health, labor force status, log of household income, and attrition. In the baseline model without optimism and with all controls, coefficients for ADL (Beta=-0.13, P<0.01) and IADL (Beta=-0.12, P<0.01) were negatively significantly associated with life satisfaction. When optimism was introduced to the model, coefficients for both ADL and IADL increased by 0.01 and remained statistically significant, which suggests some mediating effects. When interaction terms between ADL/IADL and optimism were introduced, coefficients for ADL and IADL became statistically insignificant. However, the interaction between ADL and optimism (Beta=-0.02, P<0.05) was negatively significantly associated with life satisfaction. Findings suggest that optimism may protect against the negative impact of ADL/ IADL on life satisfaction. While changes in physical functioning and mobility may influence mental health status (e.g., depression, feelings of isolation), such consequences are not inevitable. Efforts are needed to highlight the positive aspects of aging and opportunities for life enrichment to increase morale and optimism among older adults.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Shunsuke Sato ◽  
Mamoru Hashimoto ◽  
Kenji Yoshiyama ◽  
Hideki Kanemoto ◽  
Maki Hotta ◽  
...  

Abstract Background This study aimed to clarify the neuropsychiatric symptoms of right-sided predominant semantic dementia (SD-R) by comparing them with those of behavioral variant frontotemporal dementia (bvFTD), left-sided predominant SD (SD-L), and Alzheimer’s disease (AD). This study also aimed to identify clinical factors related to caregiver burden for bvFTD, SD-R, and SD-L. Methods The neuropsychiatric symptoms of 28 patients with bvFTD, 14 patients with SD-R, 24 patients with SD-L, and 43 patients with AD were evaluated using the Neuropsychiatric Inventory (NPI) and the Stereotypy Rating Inventory (SRI). Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Dementia severity was assessed using the Clinical Dementia Rating. Activities of daily living were assessed using the Lawton Instrument Activities of Daily Living (IADL) scale and the Physical Self-Maintenance Scale. We compared the NPI and SRI scores among the four groups using the Kruskal-Wallis test. In addition, clinical factors related to caregiver burden, represented by the Japanese version of the Zarit Burden Interview (J-ZBI), were analyzed using multiple regression analysis in the bvFTD, SD-R, and SD-L groups. Results The NPI total score and the NPI subscale scores of apathy and disinhibition were significantly higher in the bvFTD group than in the SD-L and AD groups. The SD-R group scores were closer to those of the bvFTD group than the SD-L group. The SRI total score and SRI subscale scores for eating and cooking and speaking were significantly higher in the bvFTD, SD-R, and SD-L groups than in the AD group. The NPI total score was significantly associated with the J-ZBI score in the bvFTD group. The NPI total score and Lawton IADL scale score were independently associated with the J-ZBI score in the SD-R group. Furthermore, the NPI total score and MMSE score were independently associated with the J-ZBI score in the SD-L group. Conclusions SD-R seemed to be a similar condition to bvFTD rather than SD-L regarding behavioral symptoms. Our results suggest that each frontotemporal dementia subgroup requires different approaches to reduce the caregiver burden.


Medicine ◽  
2021 ◽  
Vol 100 (40) ◽  
pp. e27416
Author(s):  
Keisuke Fujii ◽  
Yuya Fujii ◽  
Naruki Kitano ◽  
Ayane Sato ◽  
Kazushi Hotta ◽  
...  

2019 ◽  
Vol 35 (3) ◽  
pp. 867-877 ◽  
Author(s):  
Giedre Gefenaite ◽  
Jonas Björk ◽  
Steven M. Schmidt ◽  
Björn Slaug ◽  
Susanne Iwarsson

AbstractThere is some evidence that housing accessibility, external housing-related control beliefs (HCB) and activities of daily living (ADL) are associated in complex ways; however, these pathways have not been explored in younger old. The aim was to assess the role of external HCB in the relationship between housing accessibility and ADL by applying moderation and mediation models. This was a cross-sectional study involving 366 community-living 67–70 years old participants from the Skåne part of the Swedish National Study of Aging and Care. We assessed moderation by including an interaction term in a logistic regression analysis (significant if p value < 0.05). We assessed mediation with a series of regression analyses with effect size measures expressed as proportion mediated and its 95% confidence interval (CI). In the absence of statistically significant interaction there was no support for external HCB as a moderator. There was evidence for partial mediation as external HCB was associated with ADL when controlled for housing accessibility, while housing accessibility remained associated with independence in ADL when adjusted for external HCB. The proportion mediated was 6% (95% CI 1; 14). While the results did not support external HCB as a moderator, external HCB mediated the association between housing accessibility and ADL. These results were different from previous findings suggesting that external HCB plays a marginally significant moderating and mediating role among very old. Such differences call for further studies that would allow further exploration and validation of the findings at different stages of the ageing process, preferably utilizing longitudinal study designs.


2020 ◽  
Vol 9 (18) ◽  
Author(s):  
Kaiwang Cui ◽  
Ruixue Song ◽  
Hui Xu ◽  
Ying Shang ◽  
Xiuying Qi ◽  
...  

Background Cardiovascular risk burden has been linked to cardiovascular disease (CVD) and cognitive decline, but its association with disability is unclear. We aimed to examined the association of cardiovascular risk burden assessed by the Framingham general cardiovascular risk score (FGCRS) with the risk and progression of disability and estimated the extent to which CVD and cognitive decline mediate this association. Methods and Results A total of 1480 older adults with no disabilities (mean age=79.32±7.38 years) from the Rush Memory and Aging Project were followed for up to 21 years. FGCRS at baseline was calculated and categorized into tertiles. Disability was assessed annually with activities of daily living. The number of CVDs was calculated by summing up the CVD events. Global cognitive function was assessed annually with a battery of 19 tests. Data were analyzed using the Cox model, linear mixed effects model, and mediation analysis. At the end of the follow‐up, 713 (48.2%) participants developed disability. Compared with the lowest tertile of the FGCRS, the multiadjusted hazards ratios of disability were 1.34 (95% CI, 1.11–1.62) for the highest tertile. In addition, the highest FGCRS was associated with a change in activities of daily living score over time (β=0.057; 95% CI, 0.021–0.093). The association between FGCRS and change in activities of daily living was 13.8% mediated by the accumulation of CVDs and 25.1% by cognitive decline, respectively. Conclusions Higher cardiovascular risk burden increased the risk of disability and accelerated its progression over time. CVD accumulation and cognitive decline may partially mediate the association.


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