Factors associated with actual skeletal muscle mass increase during hip fracture rehabilitation of persons aged 80 and older

This study aimed to investigate the association between the development of dysphagia in patients with underlying sarcopenia and the prevalence of sarcopenic dysphagia in older patients following surgical treatment for hip fracture. Older female patients with hip fractures (n = 89) were studied. The data of skeletal muscle mass, hand-grip strength, and nutritional status were examined. The development of dysphagia postoperatively was graded using the Food Oral Intake Scale by a certified nurse in dysphagia nursing. The patients’ mean age was 85.9 ± 6.5 years. The prevalence of sarcopenia was 76.4% at baseline. Of the 89 patients, 11 (12.3%) and 12 (13.5%) had dysphagia by day 7 of hospitalization and at discharge, respectively. All patients who developed dysphagia had underlying sarcopenia. Lower skeletal muscle mass index (SMI) (<4.7 kg/m2) and grip strength (<8 kg) at baseline indicated a higher incidence of dysphagia on day 7 (p = 0.003 and Phi = 0.391) and at discharge (p = 0.001 and Phi = 0.448). Dysphagia developed after hip fracture surgery could be sarcopenic dysphagia, and worsening sarcopenia was a risk factor for dysphagia following hip fracture surgery. Clinicians and medical coworkers should become more aware of the risks of sarcopenic dysphagia. Early detection and preventive interventions for dysphagia should be emphasized.

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Sarcopenia in women with hip fracture: A comparison of hormonal biomarkers and their relationship to skeletal muscle mass and function

Osteoporosis and Sarcopenia ◽

10.1016/j.afos.2020.06.001 ◽

2020 ◽

Vol 6 (3) ◽

pp. 139-145

Author(s):

Ming Li Yee ◽

Raphael Hau ◽

Alison Taylor ◽

Mark Guerra ◽

Peter Guerra ◽

...

Keyword(s):

Skeletal Muscle ◽

Hip Fracture ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

And Function

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Fat mass and skeletal muscle mass in hip-fracture women: A cross-sectional study

Maturitas ◽

10.1016/j.maturitas.2006.11.003 ◽

2007 ◽

Vol 56 (4) ◽

pp. 404-410 ◽

Cited By ~ 20

Author(s):

Marco Di Monaco ◽

Fulvia Vallero ◽

Roberto Di Monaco ◽

Rosa Tappero ◽

Alberto Cavanna

Keyword(s):

Skeletal Muscle ◽

Hip Fracture ◽

Muscle Mass ◽

Fat Mass ◽

Skeletal Muscle Mass ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Factors Associated With Skeletal Muscle Mass Increase by Rehabilitation in Older Adults With Vertebral Compression Fractures

Journal of Aging and Physical Activity ◽

10.1123/japa.2020-0475 ◽

2021 ◽

pp. 1-6

Author(s):

Takahiro Ogawa ◽

Yuki Sueyoshi ◽

Shintaro Taketomi ◽

Nobumasa Chijiiwa

Keyword(s):

Skeletal Muscle ◽

Hospital Stay ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Length Of Hospital Stay ◽

Functional Independence ◽

Vertebral Compression Fractures ◽

Skeletal Muscle Index ◽

Compression Fractures ◽

Factors Associated

Age-related sarcopenia and osteoporosis-related fractures are critical health issues. Therefore, this study aimed to assess skeletal muscle mass changes in older patients with vertebral compression fractures undergoing rehabilitation and to evaluate factors associated with muscle increases. This study included 179 patients aged ≥80 years in rehabilitation wards with vertebral compression fractures. Appendicular skeletal muscle index was significantly higher at discharge (5.22 ± 1.04 kg/m2, p < .001) than on admission (5.03 ± 1.00 kg/m2). Multiple logistic regression analysis showed that length of hospital stay was significantly associated with increased skeletal muscle index (odds ratios, 1.020; 95% confidence intervals [1.000, 1.032]), whereas age, sex, body mass index, functional independence measure, protein intake, and exercise therapy duration were not. Participants with vertebral compression fractures aged ≥80 years achieved significantly increased skeletal muscle mass in rehabilitation wards. In addition, length of hospital stay was the factor independently associated with increased skeletal muscle index.

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Skeletal muscle mass, fat mass, and hip bone mineral density in elderly women with hip fracture

Journal of Bone and Mineral Metabolism ◽

10.1007/s00774-007-0752-1 ◽

2007 ◽

Vol 25 (4) ◽

pp. 237-242 ◽

Cited By ~ 25

Author(s):

Marco Di Monaco ◽

Fulvia Vallero ◽

Roberto Di Monaco ◽

Rosa Tappero ◽

Alberto Cavanna

Keyword(s):

Bone Mineral Density ◽

Skeletal Muscle ◽

Hip Fracture ◽

Muscle Mass ◽

Bone Mineral ◽

Fat Mass ◽

Skeletal Muscle Mass ◽

Elderly Women ◽

Mineral Density

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Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients

Nutrition Reviews ◽

10.1093/nutrit/nuy055 ◽

2019 ◽

Vol 77 (4) ◽

pp. 254-266 ◽

Cited By ~ 3

Author(s):

Irene Fleur Kramer ◽

Taco J Blokhuis ◽

Lex B Verdijk ◽

Luc J C van Loon ◽

Martijn Poeze

Keyword(s):

Skeletal Muscle ◽

Hip Fracture ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Nutritional Supplementation

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P1585FACTORS ASSOCIATED WITH PSOAS MUSCLE INDEX IN PATIENTS WITH MAINTENANCE DIALYSIS: FOR EARLY DETECTION OF SARCOPENIA

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa142.p1585 ◽

2020 ◽

Vol 35 (Supplement_3) ◽

Author(s):

Yoshiko Mori ◽

Tomohiro Sawada ◽

Keisuke Sunohara ◽

Akiko Owaki ◽

Hiroshi Nagaya ◽

...

Keyword(s):

Skeletal Muscle ◽

Waist Circumference ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Multiple Logistic Regression Analysis ◽

Univariate Analysis ◽

Psoas Muscle ◽

Dialysis Patients ◽

Factors Associated ◽

Maintenance Dialysis

Abstract Background and Aims Frailty was known to be associated with higher rates of hospitalization and mortality in dialysis patients, and sarcopenia was documented as the biological substrate of physical frailty. Therefore, early-detecting sarcopenia in dialysis patients is important for improving prognosis. The aim of our study was to investigate the factors associated with low skeletal muscle mass in dialysis patients. Method We recruited 134 Japanese patients (male 94, female 40; 117 maintenance hemodialysis, 11 chronic peritoneal dialysis and 6 both HD and PD) who underwent maintenance dialysis at our hospital during April 2019. Computed tomography (CT) imaging at the third lumbar vertebrae level was used to measure the psoas muscle mass index (PMI, psoas muscle area (cm2)/ height (m2) ), and low skeletal muscle mass was defined as under 6.36 cm2/m2 in male and 3.92 cm2/m2 in female. Results The prevalence of low skeletal muscle mass was 19.4% in dialysis patients (26/134). The median values of PMI were 5.13 and 7.42 cm2/m2 in low skeletal muscle mass group and normal group, respectively. Univariate analysis identified variables associated with low skeletal muscle mass as follows: gender, age, body mass index, waist circumference, presence of coronary artery disease, total protein, albumin, asparate aminotransferase, γ-glutamyl transpeptidase, phosphorus, visceral fat area and subcutaneous fat area. Multiple logistic regression analysis using above significant factors identified independent variables associated with low skeletal muscle mass as follows: gender (male) (odds ratio [OR], 12.91; 95%confidence interval [CI], 2.50-66.57; p<0.01), age (per 1 year aging) (OR, 1.07; 95%CI, 1.00-1.14; p<0.05), waist circumference (per 1cm decrease) (OR, 1.11; 95%CI, 1.04-1.19; p<0.01), and albumin (per 1g/dL decrease) (OR, 5.55; 95%CI, 1.49-19.9; p<0.05). In sub-analysis targeting only male patients, age (per 1 year aging) (OR, 1.09; 95%CI, 1.01-1.17; p<0.05), waist circumference (per 1cm decrease) (OR, 1.13; 95%CI, 1.05-1.21; p<0.01) and albumin (per 1g/dL decrease) (OR, 5.88; 95%CI, 1.39-25.9; p<0.05) were independent factors associated with low skeletal muscle mass. Conclusion In patients who underwent maintenance dialysis, age, waist circumference and albumin could be predictive factors of low skeletal muscle mass. Dialysis patients with such factors are recommended to evaluate nutritional status and physical performance to identify sarcopenia earlier and prevent progressive course of sarcopenia and frailty.

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Verification of the Nutritional and Dietary Factors Associated with Skeletal Muscle Index in Japanese Patients with Nonalcoholic Fatty Liver Disease

Canadian Journal of Gastroenterology and Hepatology ◽

10.1155/2020/3576974 ◽

2020 ◽

Vol 2020 ◽

pp. 1-10

Author(s):

Takashi Himoto ◽

Keiko Miyatake ◽

Takashi Maeba ◽

Tsutomu Masaki

Keyword(s):

Skeletal Muscle ◽

Total Energy ◽

Muscle Mass ◽

Energy Intake ◽

Skeletal Muscle Mass ◽

Dietary Factors ◽

Total Energy Intake ◽

Sarcopenic Obesity ◽

Skeletal Muscle Index ◽

Factors Associated

We sought to identify the frequencies of presarcopenia, sarcopenia, and sarcopenic obesity in patients with nonalcoholic fatty liver disease (NAFLD) and to cross-sectionally determine the nutritional and dietary factors associated with loss of skeletal muscle mass in such patients. Dietary and body component changes produced by a diet intervention were longitudinally investigated. Forty-six NAFLD patients (24 males and 22 females) were enrolled. A second diet treatment was performed at 6 months after entry in 19 of the enrolled patients (6 males and 13 females). Body compositions and dietary nutrients at six months later were compared with those at entry. Three of the 24 (13%) males and four of the 22 (18%) females fulfilled the criteria for presarcopenia and one (5%) female NAFLD patient was in the criteria for sarcopenia at baseline. None of the patients were in the criteria for sarcopenic obesity. The factors associated with skeletal muscle index in the males were body mass index (BMI), insulin-like growth factor-1, total energy intake, and lipid intake, but only BMI and bone mineral density in females at baseline. The diet intervention decreased the skeletal muscle mass in the 6 males by decreasing the total energy intake via lower protein and lipid intakes and improved their liver dysfunction. In the 13 females, a decrease in total energy intake via lower carbohydrate and lipid intake did not change the skeletal muscle mass. These results suggest that loss of skeletal muscle mass is frequently observed in nonobese NAFLD patients and that the frequency of sarcopenic obesity seems to be rare in NAFLD patients. The nutritional and dietary factors that regulate loss of skeletal muscle mass were distinct between our male and female NAFLD patients. Thus, the skeletal muscle mass of such patients as well as their body weight and liver function should be monitored during diet interventions.

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